Results 221 to 230 of about 640,739 (357)

Autologous Induced Stem‐Cell–Derived Retinal Cells for Macular Degeneration: Brief Report

New England Journal of Medicine, 2017
M. Mandai, Akira Watanabe, Y. Kurimoto, Y. Hirami, C. Morinaga, T. Daimon, M. Fujihara, H. Akimaru, Noriko Sakai, Yumiko Shibata, Motoki Terada, Yui Nomiya, Shigeki Tanishima, Masahiro Nakamura, H. Kamao, S. Sugita, A. Onishi, Tomoko Ito, Kanako Fujita, S. Kawamata, Masahiro J. Go, Chikara Shinohara, K. Hata, M. Sawada, Midori Yamamoto, Sachiko Ohta, Y. Ohara, Kenichi Yoshida, J. Kuwahara, Yuko Kitano, Naoki Amano, Masafumi Umekage, Fumiyo Kitaoka, Azusa Tanaka, Chihiro Okada, Naoko Takasu, S. Ogawa, S. Yamanaka, Masayo Takahashi   +38 more
semanticscholar   +1 more source

H105A peptide eye drops promote photoreceptor survival in murine and human models of retinal degeneration. [PDF]

Commun Med (Lond)
Bernardo-Colón A, Bighinati A, Parween S, Debnath S, Piano I, Adani E, Corsi F, Gargini C, Vergara N, Marigo V, Patricia Becerra S.   +10 more
europepmc   +1 more source

Age‐Associated Decline in Autophagy Pathways in the Retinal Pigment Epithelium and Protective Effects of Topical Trehalose in Light‐Induced Outer Retinal Degeneration in Mice

Aging Cell, EarlyView.
Transcriptomic analyses reveal an age‐related decline in autophagy pathways in RPE/choroid. These pathways remain unchanged in early AMD but become bidirectionally dysregulated in later stages, along with increased RPE loss. Pre‐treatment with trehalose eyedrops enhances RPE autophagy flux and prevents light‐induced outer retinal degeneration in mice ...
Katherine Cox, Gongyu Shi, Neve Read, Mohamed T. Patel, Kepeng Ou, Zijia Liu, Jiahui Wu, Suci Cendanawati, Jenna Le Brun Powell, Pola Goldberg Oppenheimer, Lisa J. Hill, Lindsay B. Nicholson, Andrew D. Dick, Jian Liu   +13 more
wiley   +1 more source

A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration

Science Translational Medicine, 2018
A. Kashani, J. Lebkowski, F. Rahhal, R. Avery, H. Salehi-Had, W. Dang, Chih-Min Lin, Debbie Mitra, D. Zhu, B. Thomas, Sherry. T. Hikita, B. Pennington, L. V. Johnson, D. Clegg, D. Hinton, M. Humayun   +15 more
semanticscholar   +1 more source

Mechanisms of Rhodopsin-Related Inherited Retinal Degeneration and Pharmacological Treatment Strategies. [PDF]

Cells
Azam M, Jastrzebska B.
europepmc   +1 more source

Single‐Cell RNA‐Seq Reveals Aging‐Related Impairment of Microglial Efferocytosis Contributing to Apoptotic Cells Accumulation After Retinal Injury

Aging Cell, EarlyView.
Microglia engage with apoptotic cells via cell‐surface receptors, such as proto‐oncogene tyrosine‐protein kinase MER (MerTK) and Axl; these receptors interact with the bridging molecule growth arrest‐specific 6 (Gas6) on apoptotic cells. Young microglia demonstrate efficient efferocytosis of apoptotic cells, but this process is impaired in aged ...
Pan Liu, Qi Wang, Shuimiao Wang, Ying Liu, Qiqi Chen, Wanyun Qin, Xinna Liu, Xinqi Ye, Yexuan Jiao, Huiping Yuan, Zhengbo Shao   +10 more
wiley   +1 more source

A Case of Alport’s Syndrome and Retinal Degeneration

, 2001

openalex   +1 more source

SOD2 Protects against Oxidation-Induced Apoptosis in Mouse Retinal Pigment Epithelium: Implications for Age-Related Macular Degeneration [PDF]

, 2005
Emiko Kasahara, Li-Ren Lin, Ye‐Shih Ho, Venkat N. Reddy   +3 more
openalex   +1 more source

Alterations in the balance of tubulin glycylation and glutamylation in photoreceptors leads to retinal degeneration

Journal of Cell Science, 2017
Montserrat Bosch Grau, C. Masson, Sudarshan Gadadhar, Cecilia Rocha, Olivia Tort, Patricia Marques Sousa, S. Vacher, I. Bièche, C. Janke   +8 more
semanticscholar   +1 more source

Transcorneal electrical stimulation restores DNA methylation changes in retinal degeneration. [PDF]

Front Mol Neurosci
Tew BY, Gooden GC, Lo PA, Pollalis D, Ebright B, Kalfa AJ, Gonzalez-Calle A, Thomas B, Buckley DN, Simon T, Yang Z, Iseri E, Dunton CL, Backman V, Louie S, Lazzi G, Humayun MS, Salhia B.   +17 more
europepmc   +1 more source