Results 211 to 220 of about 110,472 (262)

Oxysterols and retinal degeneration [PDF]

open access: yesBritish Journal of Pharmacology, 2021
Retinal degeneration, characterised by the progressive death of retinal neurons, is the most common cause of visual impairment. Oxysterols are the cholesterol derivatives produced via enzymatic and/or free radical oxidation that regulate cholesterol homeostasis in the retina.
Niall Strang   +2 more
exaly   +5 more sources

Modeling of retinal degeneration

Bulletin of Experimental Biology and Medicine, 2021
We developed a model of retinal degeneration in rabbits based on exposure to light with a wavelength of 405 nm. This model allows reproducing structural and functional disorders in the central parts of the retina, including primarily degeneration of the outer layers of the retina (retinal pigment epithelium and layer of photoreceptor cells), and is ...
A A, Suetov   +4 more
openaire   +2 more sources

RETINAL DEGENERATION IN GREYHOUNDS

Australian Veterinary Journal, 1980
Retinal degeneration in 10 Greyhounds with clinical and ophthalmoscopic features is described, including results of electroretinography and fluorescein angiography for one affected dog. Clinical and histologic features differed from other kinds of retinal degeneration in dogs.
D H, Slatter, J R, Blogg, I J, Constable
openaire   +2 more sources

Retinal Degeneration in Kittens

Journal of the American Veterinary Medical Association, 1973
SUMMARY Diffuse outer segment retinal degeneration was found in 2 Persian kittens in each of 2 successive litters by 15 weeks of age. Clinical signs were mydriasis, tapetal hyperreflectivity, retinal vascular attenuation, and abnormalities in visual behavior. The disease seemed to be inherited as a simple autosomal recessive trait.
L F, Rubin, D E, Lipton
openaire   +2 more sources

Retinal remodeling during retinal degeneration

Experimental Eye Research, 2005
Retinal degenerations, regardless of the initiating event or gene defect, often result in a loss of photoreceptors. This formal deafferentation of the neural retina eliminates the intrinsic glutamatergic drive of the sensory retina and, perhaps more importantly, removes coordinated Ca++-coupled signaling to the neural retina.
Bryan W, Jones, Robert E, Marc
openaire   +2 more sources

Nutrition and Retinal Degenerations

International Ophthalmology Clinics, 2000
Considerable progress has been made in the understanding and management of degenerative diseases of the retina involving photoreceptors. Nutritional approaches to treatment have proved successful in the case of the common forms of retinitis pigmentosa (supplementation with vitamin A), Bassen-Kornzweig disease (supplementation with vitamins A, E, and K),
openaire   +2 more sources

The Retinal Vasculature in Macular Degeneration

Archives of Ophthalmology, 1966
A clear understanding of the pathogenesis of macular degeneration would be a major addition to our knowledge of pathology, and more important, would give us the possibility of a rational therapy. Past work on this subject has pointed to changes in the lamina vitrea and changes in the choriocapillaris as possible origins of the breakdown that occurs.1 ...
A L, Kornzweig   +2 more
openaire   +2 more sources

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