Results 221 to 230 of about 106,393 (261)
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Neural remodeling in retinal degeneration
Progress in Retinal and Eye Research, 2003Mammalian retinal degenerations initiated by gene defects in rods, cones or the retinal pigmented epithelium (RPE) often trigger loss of the sensory retina, effectively leaving the neural retina deafferented. The neural retina responds to this challenge by remodeling, first by subtle changes in neuronal structure and later by large-scale reorganization.
Robert E, Marc +3 more
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Retinitis pigmentosa and retinal degeneration in animals: a review
Canadian Journal of Biochemistry and Cell Biology, 1984Recent biochemical findings in the human disease, retinitis pigmentosa, and related retinal degenerative diseases in animals were reviewed and discussed. While the biochemical etiology of the human disease is not known, there are indications that retinal degeneration in the rd mouse and the Irish Setter dog are related to a deficiency in cGMP ...
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Peripheral retinal degenerations and the risk of retinal detachment
American Journal of Ophthalmology, 2003To review the degenerative diseases of the peripheral retina in relationship with the risk to develop a rhegmatogenous retinal detachment and to present recommendations for use in eyes at increased risk of developing a retinal detachment.Focused literature review and author's clinical experience.Retinal degenerations are common lesions involving the ...
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Calpain activity in retinal degeneration
Journal of Neuroscience Research, 2006AbstractRetinal degenerations such as retinitis pigmentosa (RP) or glaucoma are a major cause of blindness in humans. Understanding the mechanisms underlying the various types of retinal degeneration is a pre‐requisite for the development of rational therapies for these diseases. Activation of the calcium dependent protease, calpain, has been suggested
François, Paquet-Durand +2 more
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Survival factors in retinal degenerations
Current Opinion in Neurobiology, 1994Recent experiments on the retina have examined the effectiveness of various factors (e.g. growth factors, neurotrophins and cytokines) for enhancing survival and reducing injury of retinal neurons, such as photoreceptors and ganglion cells, whose death leads to blindness in degenerative retinal diseases.
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Peripheral retinal degenerations and breaks
Albrecht von Graefes Archiv f�r Klinische und Experimentelle Ophthalmologie, 1980One-hundred-three patients referred for evaluation of peripheral retinal lesions were reviewed; 56 eyes had peripheral degenerations without breaks, 62 eyes had atrophic holes, and 88 eyes presented retinal tears. Peripheral degenerations of the snail-track and typical lattice-like types occurred with reasonable uniformity throughout the periphery and ...
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Animal Models for Retinal Degeneration
2009Retinal degeneration is often used to describe a category of human eye diseases, which are characterized by photoreceptor loss leading to severe visual impairment and blindness. An important, yet heterogeneous group of such diseases is called Retinitis Pigmentosa (RP).
Samardzija, M +4 more
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Retinal Degeneration in a Baboon
American Journal of Ophthalmology, 1974S J, Vainisi, B B, Beck, D J, Apple
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Retinal Degeneration in the Dog and Cat
Veterinary Clinics of North America: Small Animal Practice, 1990Retinal degenerations in the dog and cat are an important cause of blindness in these species. Particularly in the dog, many retinal degenerations, collectively called progressive retinal atrophy, seen in clinical practice are inherited. The clinical signs, electrophysiological findings, pathology, and underlying biochemical defects in the retina vary ...
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