Results 221 to 230 of about 110,472 (262)

Lipid peroxidation and retinal degeneration

Current Eye Research, 1984
Retinal degenerations were produced in albino rats by exposure to constant illumination or in frogs and albino rats by intravitreal injections of ferrous sulfate. Both treatments resulted in the loss of long-chain polyunsaturated fatty acids and the accumulation of lipid hydroperoxides in isolated rod outer segments.
R E, Anderson, L M, Rapp, R D, Wiegand
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Retinitis pigmentosa and retinal degeneration in animals: a review

Canadian Journal of Biochemistry and Cell Biology, 1984
Recent biochemical findings in the human disease, retinitis pigmentosa, and related retinal degenerative diseases in animals were reviewed and discussed. While the biochemical etiology of the human disease is not known, there are indications that retinal degeneration in the rd mouse and the Irish Setter dog are related to a deficiency in cGMP ...
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Neural remodeling in retinal degeneration

Progress in Retinal and Eye Research, 2003
Mammalian retinal degenerations initiated by gene defects in rods, cones or the retinal pigmented epithelium (RPE) often trigger loss of the sensory retina, effectively leaving the neural retina deafferented. The neural retina responds to this challenge by remodeling, first by subtle changes in neuronal structure and later by large-scale reorganization.
Robert E, Marc, Bryan W, Jones, Carl B, Watt, Enrica, Strettoi   +3 more
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Peripheral retinal degenerations and the risk of retinal detachment

American Journal of Ophthalmology, 2003
To review the degenerative diseases of the peripheral retina in relationship with the risk to develop a rhegmatogenous retinal detachment and to present recommendations for use in eyes at increased risk of developing a retinal detachment.Focused literature review and author's clinical experience.Retinal degenerations are common lesions involving the ...
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Peripapillary Pigmentary Retinal Degeneration

American Journal of Ophthalmology, 1978
We studied four patients with peripapillary pigmentary retinal degeneration, an asymptomatic disorder that was probably benign and nonprogressive. The ophthalmoscopic appearance showed a segmental, grayish metallic sheen in association with bone spicule pigmentation, which radiated from the disk along the temporal vessel arcades and joined temporal to ...
K G, Noble, R E, Carr
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Feline Central Retinal Degeneration

Journal of the American Veterinary Medical Association, 1970
SUMMARY Feline central retinal degeneration (fcrd) was found in 25 domestic cats. It was characterized by a focus of retinal degeneration in the macular region involving the outer retinal layers. The cause of this condition was undetermined.
R W, Bellhorn, C A, Fischer
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Survival factors in retinal degenerations

Current Opinion in Neurobiology, 1994
Recent experiments on the retina have examined the effectiveness of various factors (e.g. growth factors, neurotrophins and cytokines) for enhancing survival and reducing injury of retinal neurons, such as photoreceptors and ganglion cells, whose death leads to blindness in degenerative retinal diseases.
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Retinal Degeneration in the Dog and Cat

Veterinary Clinics of North America: Small Animal Practice, 1990
Retinal degenerations in the dog and cat are an important cause of blindness in these species. Particularly in the dog, many retinal degenerations, collectively called progressive retinal atrophy, seen in clinical practice are inherited. The clinical signs, electrophysiological findings, pathology, and underlying biochemical defects in the retina vary ...
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800 Facets of Retinal Degeneration

2011
In today's world of genomics and large computational analyses, rapid progress has been made in identifying genes associated with human retinal diseases. Nevertheless, before significant advances toward effective therapeutic intervention is made, a clearer understanding of the molecular and cellular role of these gene products in normal and diseased ...
T, Cook, A, Zelhof, M, Mishra, J, Nie
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Peripheral retinal degenerations and breaks

Albrecht von Graefes Archiv f�r Klinische und Experimentelle Ophthalmologie, 1980
One-hundred-three patients referred for evaluation of peripheral retinal lesions were reviewed; 56 eyes had peripheral degenerations without breaks, 62 eyes had atrophic holes, and 88 eyes presented retinal tears. Peripheral degenerations of the snail-track and typical lattice-like types occurred with reasonable uniformity throughout the periphery and ...
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