Results 31 to 40 of about 311,535 (246)

Diabetic retinopathy: could the alpha-1 antitrypsin be a therapeutic option? [PDF]

open access: yes, 2014
Diabetic retinopathy is one of the most important causes of blindness. The underlying mechanisms of this disease include inflammatory changes and remodeling processes of the extracellular-matrix (ECM) leading to pericyte and vascular endothelial cell ...
Chuluyan, Hector Eduardo   +3 more
core   +1 more source

Diagnosis and Treatment of Primary Inflammatory Choriocapillaropathies (PICCPs): A Comprehensive Overview

open access: yesMedicina, 2022
Purpose: Primary inflammatory choriocapillaropathies (PICCPs) belong to a group of intraocular inflammatory diseases with the common characteristic of inflammatory choriocapillaris hypo- or non-perfusion as the main clinicopathological mechanism.
Ioannis Papasavvas, Carl P. Herbort
doaj   +1 more source

Sphingolipids as emerging mediators in retina degeneration [PDF]

open access: yes, 2019
The sphingolipids ceramide (Cer), sphingosine-1-phosphate (S1P), sphingosine (Sph), and ceramide-1-phosphate (C1P) are key signaling molecules that regulate major cellular functions.
Prado Spalm, Facundo Heber   +3 more
core   +1 more source

Retinoids and Retinal Diseases [PDF]

open access: yesAnnual Review of Vision Science, 2016
Recent progress in molecular understanding of the retinoid cycle in mammalian retina stems from painstaking biochemical reconstitution studies supported by natural or engineered animal models with known genetic lesions and studies of humans with specific genetic blinding diseases.
Kiser, Philip, Palczewski, Krzysztof
openaire   +4 more sources

Retinal blood vessels extraction using probabilistic modelling [PDF]

open access: yes, 2014
© 2014 Kaba et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
A Hoover   +22 more
core   +1 more source

When HIV Immunodeficiency and Heterochromia Confuse the Issue: Recurrent Zoster Uveitis Mistaken for Fuchs’ Uveitis

open access: yesJournal of Ophthalmic & Vision Research, 2021
Purpose: We report a case with iris heterochromia misdiagnosed as Fuchs' uveitis which finally turned out to be a unilateral zoster uveitis in an HIV-positive patient.
Ioannis Papasavvas   +2 more
doaj   +1 more source

Diagnosis of Inherited Retinal Diseases [PDF]

open access: yesKlinische Monatsblätter für Augenheilkunde, 2021
AbstractInherited retinal diseases are a frequent cause of severe visual impairment or blindness in children and adults of working age. Across this group of diseases, there is great variability in the degree of visual impairment, the impact on everyday life, disease progression, and the suitability to therapeutic intervention.
Johannes Birtel   +4 more
openaire   +3 more sources

Cholesterol oxidation in the retina: implications of 7KCh formation in chronic inflammation and age-related macular degeneration

open access: yesJournal of Lipid Research, 2010
This review will discuss the formation and potential implications of 7-ketocholesterol (7KCh) in the retina. 7KCh is a proinflammatory oxysterol known to be present in high amounts in oxidized LDL deposits associated with atheromatous plaques.
Ignacio R. Rodríguez   +1 more
doaj   +1 more source

Preoperative Steroid Use in Rhegmatogenous Retinal Detachment Associated with Choroidal Detachment after 23-Gauge Vitrectomy

open access: yesJournal of Ophthalmology, 2020
Background. Rhegmatogenous retinal detachment associated with choroidal detachment (RRDCD) is rare and the prognosis is poor. This retrospective study evaluated the effect of preoperative steroid on the clinical outcome of patients with RRDCD receiving ...
Jianhua Wu   +4 more
doaj   +1 more source

Clinicopathology of non-infectious choroiditis: evolution of its appraisal during the last 2–3 decades from “white dot syndromes” to precise classification

open access: yesJournal of Ophthalmic Inflammation and Infection, 2021
Choroidal imaging investigation techniques were very limited until 2–3 decades ago. Fluorescein angiography (FA) was not suited for the analysis of the choroidal compartment and B-scan ultrasonography did not provide enough accuracy.
Carl P. Herbort   +2 more
doaj   +1 more source

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