Results 41 to 50 of about 277,755 (206)

Therapeutic approaches with intravitreal injections in geographic atrophy secondary to age-related macular degeneration: current drugs and potential molecules [PDF]

, 2019
The present review focuses on recent clinical trials that analyze the efficacy of intravitreal therapeutic agents for the treatment of dry age-related macular degeneration (AMD), such as neuroprotective drugs, and complement inhibitors, also called ...
Cerini, Alberto, Greco A., La Cava M, Lambiase A, Limoli PG, Nebbioso M   +5 more
core   +1 more source

Feature Representation Learning for Robust Retinal Disease Detection from Optical Coherence Tomography Images [PDF]

arXiv, 2022
Ophthalmic images may contain identical-looking pathologies that can cause failure in automated techniques to distinguish different retinal degenerative diseases. Additionally, reliance on large annotated datasets and lack of knowledge distillation can restrict ML-based clinical support systems' deployment in real-world environments.
arxiv  

Laser flare photometry: a cost-effective method for early detection of endophthalmitis after intravitreal injection of anti-VEGF agents

Journal of Ophthalmic Inflammation and Infection, 2018
Background Intravitreal injection of anti-vascular endothelial growth factor agents is the most common intraocular procedure worldwide, inevitably causing more cases of post-injection endophthalmitis. The purpose of this study was to evaluate the utility
Vânia Lages, Béatrice Gehrig, Carl P. Herbort   +2 more
doaj   +1 more source

Optic-Net: A Novel Convolutional Neural Network for Diagnosis of Retinal Diseases from Optical Tomography Images [PDF]

, 2019
Diagnosing different retinal diseases from Spectral Domain Optical Coherence Tomography (SD-OCT) images is a challenging task. Different automated approaches such as image processing, machine learning and deep learning algorithms have been used for early detection and diagnosis of retinal diseases.
arxiv   +1 more source

Microscopic Inner Retinal Hyper-reflective Phenotypes in Retinal and Neurologic Disease [PDF]

, 2014
Purpose. We surveyed inner retinal microscopic features in retinal and neurologic disease using a reflectance confocal adaptive optics scanning light ophthalmoscope (AOSLO). Methods. Inner retinal images from 101 subjects affected by one of 38 retinal or
Carroll, Joseph, Cooper, Robert F., Dubis, Adam M., Dubra, Alfredo, Higgins, Brian P., Kim, Judy E., Scoles, Drew, Stepien, Kimberly E., Summerfelt, Phyllis, Weinberg, David V.   +9 more
core   +2 more sources

Molecular Analysis of Prothrombotic Gene Variants in Venous Thrombosis: A Potential Role for Sex and Thrombotic Localization [PDF]

, 2020
Background: Requests to test for thrombophilia in the clinical context are often not evidence-based. Aim: To define the role of a series of prothrombotic gene variants in a large population of patients with different venous thromboembolic diseases ...
AMATO, FELICE, BRUZZESE, DARIO, CASTALDO, GIUSEPPE, CERNERA, Gustavo, COMEGNA, Marika, DI LULLO, ANTONELLA MIRIAM, DI MINNO, ALESSANDRO, ELCE, AUSILIA, LIGUORI, RENATO, ZARRILLI, FEDERICA   +9 more
core   +1 more source

Varicella-zoster virus reactivation causing herpes zoster ophthalmicus (HZO) after SARS-CoV-2 vaccination – report of three cases

Journal of Ophthalmic Inflammation and Infection, 2021
Purpose We are reporting 3 patients who presented acute zoster ophthalmicus (HZO), an activation of varicella-zoster virus, after mRNA anti-SARS-CoV-2 vaccination, seen directly or referred to our center.
Ioannis Papasavvas, Christian de Courten, Carl P. Herbort   +2 more
doaj   +1 more source

Sphingolipids as emerging mediators in retina degeneration [PDF]

, 2019
The sphingolipids ceramide (Cer), sphingosine-1-phosphate (S1P), sphingosine (Sph), and ceramide-1-phosphate (C1P) are key signaling molecules that regulate major cellular functions.
Prado Spalm, Facundo Heber, Rotstein, Nora Patricia, Simon, Maria Victoria, Vera, Marcela Sonia   +3 more
core   +1 more source

Structural and Vascular Features of Macula Related to the Recurrence of Macular Edema in Central Retinal Vein Occlusion After Anti-VEGF Therapy

Journal of Ophthalmology
Conclusion: With prolonged CRVO duration, more anti-VEGF injections, and more retinal photocoagulation procedures, retinal, choroidal, and vascular atrophy in the macula occurs in CRVO eyes, making ME less likely to recur.
Dazhuang Ren, Cece Zhao, Gaoxu Wei, Xiaoyun Hou, Chang Li, Zhiqing Li   +5 more
doaj   +1 more source

Idiopathic multifocal choroiditis (MFC): aggressive and prolonged therapy with multiple immunosuppressive agents is needed to halt the progression of active disease. An offbeat review and a case series

Journal of Ophthalmic Inflammation and Infection, 2022
Background and purpose Idiopathic multifocal choroiditis (MFC) is part of the group of choriocapillaritis entities. The clinical definition of the disease has evolved with time. The aim of this article was to undertake a review on MFC, on its present-day
Ioannis Papasavvas, Piergiorgio Neri, Alessandro Mantovani, Carl P. Herbort   +3 more
doaj   +1 more source