Results 71 to 80 of about 321,318 (176)
Quantitative and Qualitative Evaluation of Explainable Deep Learning Methods for Ophthalmic Diagnosis [PDF]
Background: The lack of explanations for the decisions made by algorithms such as deep learning has hampered their acceptance by the clinical community despite highly accurate results on multiple problems. Recently, attribution methods have emerged for explaining deep learning models, and they have been tested on medical imaging problems.
arxiv
Existing drusen measurement is difficult to use in clinic because it requires a lot of time and effort for visual inspection. In order to resolve this problem, we propose an automatic drusen detection method to help clinical diagnosis of age-related ...
Y. J. Kim, K. Kim
semanticscholar +1 more source
Optic disc drusen (ODD) are calcific deposits that form in the optic nerve head secondary to abnormalities in axonal metabolism and degeneration. Anterior ischemic optic neuropathy, central retinal artery, and vein occlusion are among the rare vascular ...
Ziya Ayhan+3 more
doaj +1 more source
Abstract Purpose This trial evaluated the noninferiority of a relaxed compared to a strict treat‐and‐extend treatment strategy in patients with neovascular Age‐related macular degeneration (AMD). Methods Multicenter, randomized, controlled, phase IV, non‐inferiority clinical trial.
Damian Jaggi+9 more
wiley +1 more source
Druse-Induced Morphology Evolution in Retinal Pigment Epithelium [PDF]
The retinal pigment epithelium (RPE) is a key site of pathogenesis for many retina diseases. The formation of drusen in the retina is characteristic of retinal degeneration. We investigate morphological changes in the RPE in the presence of soft drusen using an integrated experimental and modeling approach. We collect RPE flat mount images from donated
arxiv
Drusen are a hallmark lesion of age-related macular degeneration (AMD) and changes in their area and/or volume are strongly associated with disease progression. Assessment of longitudinal change in drusen size in clinical practice however is limited to a
Judy Nam+3 more
doaj +1 more source
ABSTRACT Optical coherence tomography angiography is a burgeoning imaging modality in Ophthalmology. In this review, we outline the breadth of potential utility for optical coherence tomography angiography for diagnosis and prognostication in neuro‐ophthalmology.
Marzieh Tahmasebi Sarvestani+2 more
wiley +1 more source
JOINED : Prior Guided Multi-task Learning for Joint Optic Disc/Cup Segmentation and Fovea Detection [PDF]
Fundus photography has been routinely used to document the presence and severity of various retinal degenerative diseases such as age-related macula degeneration, glaucoma, and diabetic retinopathy, for which the fovea, optic disc (OD), and optic cup (OC) are important anatomical landmarks.
arxiv
Clinical Characteristics of Neovascular Age-Related Macular Degeneration without Typical Drusen
Purpose. To evaluate the clinical characteristics of neovascular age-related macular degeneration (nAMD) patients without typical drusen. Methods. We retrospectively studied 165 eyes in 165 patients with treatment-naïve nAMD, including typical AMD and ...
Hiroyuki Kamao+5 more
doaj +1 more source
Abstract Purpose To quantify ellipsoid zone (EZ) loss during anti‐VEGF therapy for neovascular age‐related macular degeneration (nAMD) and correlate these findings with nAMD disease activity using artificial intelligence‐based algorithms. Methods Spectral domain optical coherence tomography (Spectralis, Heidelberg Engineering) images from nAMD ...
Virginia Mares+7 more
wiley +1 more source