Results 71 to 80 of about 321,318 (176)

Quantitative and Qualitative Evaluation of Explainable Deep Learning Methods for Ophthalmic Diagnosis [PDF]

open access: yesarXiv, 2020
Background: The lack of explanations for the decisions made by algorithms such as deep learning has hampered their acceptance by the clinical community despite highly accurate results on multiple problems. Recently, attribution methods have emerged for explaining deep learning models, and they have been tested on medical imaging problems.
arxiv  

Automated Segmentation Methods of Drusen to Diagnose Age-Related Macular Degeneration Screening in Retinal Images

open access: yesComput. Math. Methods Medicine, 2018
Existing drusen measurement is difficult to use in clinic because it requires a lot of time and effort for visual inspection. In order to resolve this problem, we propose an automatic drusen detection method to help clinical diagnosis of age-related ...
Y. J. Kim, K. Kim
semanticscholar   +1 more source

Unilateral Acute Anterior Ischemic Optic Neuropathy in a Patient with an Already Established Diagnosis of Bilateral Optic Disc Drusen

open access: yesCase Reports in Ophthalmological Medicine, 2015
Optic disc drusen (ODD) are calcific deposits that form in the optic nerve head secondary to abnormalities in axonal metabolism and degeneration. Anterior ischemic optic neuropathy, central retinal artery, and vein occlusion are among the rare vascular ...
Ziya Ayhan   +3 more
doaj   +1 more source

Comparison of treatment routine using aflibercept: Strict vs. relaxed retreatment regimen (TOLERANT study)—A non‐inferiority, randomized controlled trial

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose This trial evaluated the noninferiority of a relaxed compared to a strict treat‐and‐extend treatment strategy in patients with neovascular Age‐related macular degeneration (AMD). Methods Multicenter, randomized, controlled, phase IV, non‐inferiority clinical trial.
Damian Jaggi   +9 more
wiley   +1 more source

Druse-Induced Morphology Evolution in Retinal Pigment Epithelium [PDF]

open access: yesarXiv, 2016
The retinal pigment epithelium (RPE) is a key site of pathogenesis for many retina diseases. The formation of drusen in the retina is characteristic of retinal degeneration. We investigate morphological changes in the RPE in the presence of soft drusen using an integrated experimental and modeling approach. We collect RPE flat mount images from donated
arxiv  

Multispectral pattern recognition measures change in drusen area in age-related macular degeneration with high congruency to expert graders

open access: yesScientific Reports, 2022
Drusen are a hallmark lesion of age-related macular degeneration (AMD) and changes in their area and/or volume are strongly associated with disease progression. Assessment of longitudinal change in drusen size in clinical practice however is limited to a
Judy Nam   +3 more
doaj   +1 more source

Correlation of Structure With Function: Future Utilities for Optical Coherence Tomography Angiography in Neuro‐Ophthalmology

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Optical coherence tomography angiography is a burgeoning imaging modality in Ophthalmology. In this review, we outline the breadth of potential utility for optical coherence tomography angiography for diagnosis and prognostication in neuro‐ophthalmology.
Marzieh Tahmasebi Sarvestani   +2 more
wiley   +1 more source

JOINED : Prior Guided Multi-task Learning for Joint Optic Disc/Cup Segmentation and Fovea Detection [PDF]

open access: yesarXiv, 2022
Fundus photography has been routinely used to document the presence and severity of various retinal degenerative diseases such as age-related macula degeneration, glaucoma, and diabetic retinopathy, for which the fovea, optic disc (OD), and optic cup (OC) are important anatomical landmarks.
arxiv  

Clinical Characteristics of Neovascular Age-Related Macular Degeneration without Typical Drusen

open access: yesJournal of Ophthalmology, 2021
Purpose. To evaluate the clinical characteristics of neovascular age-related macular degeneration (nAMD) patients without typical drusen. Methods. We retrospectively studied 165 eyes in 165 patients with treatment-naïve nAMD, including typical AMD and ...
Hiroyuki Kamao   +5 more
doaj   +1 more source

Correlation of retinal fluid and photoreceptor and RPE loss in neovascular AMD by automated quantification, a real‐world FRB! analysis

open access: yesActa Ophthalmologica, Volume 103, Issue 3, Page 295-303, May 2025.
Abstract Purpose To quantify ellipsoid zone (EZ) loss during anti‐VEGF therapy for neovascular age‐related macular degeneration (nAMD) and correlate these findings with nAMD disease activity using artificial intelligence‐based algorithms. Methods Spectral domain optical coherence tomography (Spectralis, Heidelberg Engineering) images from nAMD ...
Virginia Mares   +7 more
wiley   +1 more source

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