Results 81 to 90 of about 11,541 (214)

Prevalence of retinal pathologies in people over 60 years: the Tehran Geriatrics Eye Study [PDF]

open access: yesInternational Journal of Ophthalmology
AIM: To determine the prevalence of some retinal pathologies in people over 60y and their association with demographic and ocular factors. METHODS: A cross-sectional study was conducted in Tehran using multistage cluster sampling.
Abolghasem Mortazavi   +5 more
doaj   +1 more source

Investigating the effects of complement loci CFH and ARMS2/HTRA1 on Alzheimer Disease

open access: yesAlzheimer's &Dementia, Volume 21, Issue S1, December 2025.
Abstract Background Late‐onset Alzheimer Disease (LOAD) shares multiple pathologic features and genetic risk factors with Age‐related Macular Degeneration (AMD). Amyloid‐beta (Ab) forms amyloid plaques in the brain and aggregates with other proteins and lipids to form drusen deposits in the retina of AMD eyes.
Noel C. Moore   +25 more
wiley   +1 more source

Eye diseases and dementia: association because of pathogenesis or visual impairment?

open access: yesAlzheimer's &Dementia, Volume 21, Issue S6, December 2025.
Abstract Background Research suggests a link between blindness, age‐related macular degeneration (AMD), and a higher risk of dementia. Since AMD can lead to blindness, it remains unclear whether this elevated risk is due to the disease's underlying pathology or its ability to cause blindness.
Xinyu Gu   +4 more
wiley   +1 more source

Investigating causal associations of circulating micronutrient concentrations with the risk of age‐related macular degeneration and diabetic retinopathy: A Mendelian randomization study

open access: yesEye &ENT Research, Volume 2, Issue 4, Page 264-274, December 2025.
Abstract Background Age‐related macular degeneration (AMD) and diabetic retinopathy (DR) are two prevalent retinal neovascular diseases globally. Although observational studies have suggested a link between micronutrients and both AMD and DR, the causal relationship remains unconfirmed.
Chengzhi Liu   +4 more
wiley   +1 more source

Diagnostics of optic disk drusen in children

open access: yesOftalʹmologiâ, 2016
Diagnosis of deep optic disc drusen (OND) in children is difficult because they are not visualized ophthalmoscopically and often mimic a picture of stagnation, identifying the wrong tactics diagnostic and therapeutic actions.Materials and Methods ...
A. G. Shchuko   +3 more
doaj   +1 more source

Apolipoprotein Localization in Isolated Drusen and Retinal Apolipoprotein Gene Expression

open access: yesInvestigative Opthalmology & Visual Science, 2006
To evaluate apolipoprotein (Apo) gene expression in native human retinal pigment epithelium (RPE) and neurosensory retina and to detect apolipoproteins within age-related, extramacular drusen.Drusen were isolated manually from 10 eyes of 10 donors (age range, 58-93 years) with grossly normal maculas that were preserved in 4% paraformaldehyde within 6 ...
Chuan-Ming, Li   +3 more
openaire   +2 more sources

Changes of drusen number and central retinal thickness in age-related macular degeneration patients over two years

open access: yesActa Clinica Croatica, 2016
Age-related macular degeneration (ARMD) is the leading cause of blindness in developed world but there are still much unknown facts about the disease itself.
Krešimir Mandić   +4 more
doaj   +1 more source

Automated detection of retinal exudates and drusen in ultra-widefield fundus images based on deep learning [PDF]

open access: bronze, 2021
Zhongwen Li   +16 more
openalex   +1 more source

Optic Disc Abnormalities – Diagnosis, Evolution and Influence on Visual Acuity

open access: yesBiomolecules & Biomedicine, 2010
Congenital abnormalities of the optic disc are not so rare. The etiology for the most of them is unknown. Visual acuity of affected eye may be minimally or severely affected, depending on the extent of lesion. All of these conditions can be unilateral or
Sonja Cekić   +4 more
doaj   +1 more source

Genomewide Association Study of Retinal Traits in the Amish Reveals Loci Influencing Drusen Development and Link to Age-Related Macular Degeneration

open access: gold, 2022
Michael D. Osterman   +7 more
openalex   +1 more source

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