Results 151 to 160 of about 5,405,992 (262)

Chick PTPσ regulates the targeting of retinal axons within the optic tectum [PDF]

open access: yes, 2002
Chick PTP (cPTP), also known as CRYP, is a receptor-like protein tyrosine phosphatase found on axons and growth cones. Putative ligands for cPTP are distributed within basement membranes and on glial end feet of the retina, optic nerve, and optic tectum,
Aricescu, AR   +4 more
core  

Optical Stimulation and Monitoring of the Peripheral Nervous System: Perspectives and Challenges Toward Clinical Translation

open access: yesLaser &Photonics Reviews, EarlyView.
Optical neuromodulation with IR light allows stimulation of the PNS without the need for physical contact with the target nerve or without requiring any genetic modification. The clinical translation of this technique will pave the way to the development of neural interfaces for restoring sensory feedback in individuals with limb amputation.
Federica Piccirillo   +20 more
wiley   +1 more source

Induction of Gene Expression After Retinal Ganglion Cell Axotomy

open access: yes, 2013
Death of retinal ganglion cells is the final common pathway underlying virtually all disease of the optic nerve, including anterior ischemic optic neuropathy, optic neuritis, and compressive optic neuropathy. The mechanism by which retinal ganglion cells
Leonard A. Levin; K. Geszvain
core  

Deciphering the genetics of retinal ganglion cell development using CRISPT/Cas9 genome editing in zebrafish. [PDF]

open access: yes, 2016
Retinal ganglion cells are specialized nerve cells in the eye. These specialized nerve cells develop from progenitor cells following an intricate pattern of gene expression.
Weerasinghe, Sanjeeva
core  

Parkinson's Disease and Retinal Age Gap: A Cross‐Sectional Analysis

open access: yesMovement Disorders, EarlyView.
Abstract Background Deep‐learning models are capable of predicting age from retinal scans and the difference between this and chronological age, retinal age gap, has been shown to be significantly associated with risk of mortality, cardiovascular diseases, and kidney failure.
Akshay Narayan   +9 more
wiley   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

open access: yesNeuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi   +5 more
wiley   +1 more source

CRITICAL NEUROPROTECTIVE ROLE OF CAVEOLINS IN THE RETINAL GANGLION CELLS

open access: yes, 2012
CRITICAL NEUROPROTECTIVE ROLE OF CAVEOLINS IN THE RETINAL GANGLION ...
Vivek Gupta (13420509)   +3 more
core  

A Retinomorphic Graphene Transistor Implementing Direction‐ and Velocity‐Selective Computation for In‐Sensor Image Stabilization

open access: yesSmall, EarlyView.
A multi‐gated ion‐gel graphene transistor architecture emulates spatiotemporal dendritic filtering inspired by biological direction‐selective retinal circuits. Leveraging distributed resistance‐capacitive ionic relaxation delays under combined excitation‐inhibition pulse routines, the solid‐state device exhibits programmable direction‐selective index ...
Jun Ha Park   +11 more
wiley   +1 more source

Gut microbiota dysbiosis in the inflammatory pathogenesis of diabetic retinopathy

open access: yesVIEW, EarlyView.
This graphical abstract illustrates how gut dysbiosis drives diabetic retinopathy through the gut‐retina axis, a process unfolding in three interconnected stages. First, in the gut, a decrease in beneficial bacteria and an increase in pro‐inflammatory taxa compromise the intestinal barrier, causing a “leaky gut” that allows LPS to translocate into the ...
Junyan Hu, Jingxiang Zhong
wiley   +1 more source

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