Results 141 to 150 of about 5,405,992 (262)

Spontaneous retinal ganglion cell responses are preserved under hypothermic conditions.

, 2016
Bar graph represents the relative amount of electrodes measuring spontaneous retinal ganglion cell activity per retina. Spontaneous action potentials of retinal ganglion cells were measured simultaneously by the 60 electrodes of a Multi-Electrode-Array ...
Blanca Arango-Gonzalez (168856), Karl U. Bartz-Schmidt (167658), Sven Schnichels (2155807), Martin S. Spitzer (2155801), Marita Feldkaemper (652432), Jose Hurst (2155810), Maximilian Schultheiss (519673), Thoralf Hermann (2155804), Guenther Zeck (621257), Marius Ueffing (26602)   +9 more
core   +1 more source

Endogenous Trigeminal Neurons Induce Schwann Differentiation of Donor Stem Cells in Dental Pulp Regeneration via Reciprocal Extracellular Vesicles Interplay

Exploration, EarlyView.
Our study demonstrates that the host TG coordinates with heterologously implanted SHED to regenerate functional dental pulp through reciprocal EVs’ interplay. EVs derived from implanted stem cells migrate to the host TG to activate axonal regeneration.
Wanmin Zhao, Wenzhe Wang, Jia Guo, Jiani Liu, Wei Wang, Dihao Tao, Jiayi Dong, Zhonghan Li, Shiyu Liu, Songtao Shi, Tao Chen, Yan Jin, Bei Li   +12 more
wiley   +1 more source

The regulatory role of mitochondrial quality control and post-translational modification in ganglion cell injury caused by retinal ischemia–reperfusion

European Journal of Medical Research
Retinal ganglion cell injury is an irreversible common pathological process caused by retinal ischemia–reperfusion resulting from various ocular diseases, which can lead to vision loss and blindness.
Yige Zhang, Yulin Guo, Mei Sun, Jing Xu, Mengjiao Zhang, Zhenzhen Gu, Like Xie, Xiaofeng Hao   +7 more
doaj   +1 more source

Bio‐inspired vision: From principle, material architectures to system‐level integration

FlexMat, EarlyView.
This review introduces the development and mechanism of electronic and ionic bio‐inspired vision devices respectively. Then, it explores the impact of structure on bio‐inspired visual performance from the scale of intrinsic materials and device. Finally, it concludes that only by combining advanced software and technology can more complex vision ...
Zewan Lin, Miaoyi Xu, Xianda Ma, Weifeng Yang, Yuanlong Shao   +4 more
wiley   +1 more source

Organic electrochemical transistors for neural recording and modulation: From mixed‐conduction physics to closed‐loop biointerfaces

InfoMat, EarlyView.
OECT‐based neural interfaces integrate mixed ionic‐electronic transduction, soft biointegration, multimodal sensing, and closed‐loop modulation, enabling adaptive recording, neurochemical monitoring, and intelligent therapeutic strategies. Abstract Next‐generation neural interfaces increasingly aim to couple neural recording with local processing and ...
Chao Zhao, Zhongqing Sun, Shijie Wang, Bingjun Wang, Zixuan Yuan, Yaomin Guo, Jie Zhao, Leyuan Li, Xiaomu Wang, Wen Jiang, Wei Ma   +10 more
wiley   +1 more source

Oral nicotinamide provides robust, dose-dependent structural and metabolic neuroprotection of retinal ganglion cells in experimental glaucoma

Acta Neuropathologica Communications
A compromised capacity to maintain NAD pools is recognized as a key underlying pathophysiological feature of neurodegenerative diseases. NAD acts as a substrate in major cell functions including mitochondrial homeostasis, cell signalling, axonal ...
Gloria Cimaglia, James R. Tribble, Marcela Votruba, Pete A. Williams, James E. Morgan   +4 more
doaj   +1 more source

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

iNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin, Xianfeng Yu, Yayu Wang, Xiaohan Song, Yuehua Wang, Zhixin Wang, Wei Miao, Xudong Yang, Jiajia Zhu, Xiaoqun Zhu, Maria‐Trinidad Herrero   +10 more
wiley   +1 more source

Optic Nerve Thickness Assessed by Ocular Ultrasonography in Obstructive Sleep Apnea

Journal of Ultrasound in Medicine, EarlyView.
Objectives Obstructive sleep apnea (OSA) has been associated with various ocular complications, yet ultrasonographic evaluation of optic nerve thickness and its relationship with nocturnal hypoxemia remains poorly understood. This study aimed to evaluate optic nerve thickness and globe dimensions using ocular ultrasonography in patients with different ...
Buğra Kerget, Eyüp Çetin, Alperen Aksakal, Sırma Merve Çetin, Mustafa Buğra Coşkuner   +4 more
wiley   +1 more source

Orbital Lymphatic Malformations Are Associated With Intracranial Vascular Anomalies

The Laryngoscope, EarlyView.
In this retrospective series, all seven patients with orbital lymphatic malformations had intracranial vascular anomalies consistent with cerebrofacial venous metameric syndrome and hotspot PIK3CA variants identified through tissue‐based sequencing. Five patients treated with alpelisib experienced symptom improvement within 6 months.
Kelsey A. Loy, Jennifer Siu, Clare Richardson, J. Nathaniel Perkins, Kaitlyn Zenner, Kevin Koo, Francisco Perez, James Bennett, Randall Bly, Danial K. Hallam, Amy Geddis, Jonathan A. Perkins   +11 more
wiley   +1 more source

Retinal Ganglion Cell Responses to Low-frequency Focused Ultrasound Stimulation

, 2017
PURPOSE: Acoustic retinal prosthesis has been put forward using high-frequency US with non-invasive and high-resolution advantages. But its application is limited by the difficulties in fabrication, energy consumption and acoustic attenuation.
Qiuju Jiang, Weibao Qiu, Huixia Zhao, Guofeng Li   +3 more
core