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Culture of rat retinal ganglion cells

Journal of Huazhong University of Science and Technology [Medical Sciences], 2011
This study aimed to modify the mixed and purified culture of rat retinal ganglion cells (RGCs) in vitro. The retinae of 1-3 day old Sprague-Dawley (SD) rats were separated bluntly into two layers: inner layer and outer layer, under a surgical microscope. Retinal cells isolated from different layers (inner layer, outer layer and whole retinal tissue) by
Zhirong, Xu   +4 more
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Retinal Ganglion Cells

1988
Ganglion cells typically make up the innermost layer of the vertebrate retina. They are the only cells with axons that leave the eye. These axons form the optic nerve. Ganglion cell dendrites ramify in the inner nuclear layer, where they are postsynaptic to bipolar cells, which provide a direct input pathway from the outer plexiform layer, and to ...
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Classification of turtle retinal ganglion cells

Journal of Neurophysiology, 1989
1. Receptive fields of 78 retinal ganglion cells were analyzed for their responses to moving and stationary lights that were presented under a variety of stimulus conditions. All cells were sensitive to moving stimuli, and their receptive fields often comprised excitatory and inhibitory sub-regions. 2.
A M, Granda, J E, Fulbrook
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Topography of pig retinal ganglion cells

Journal of Comparative Neurology, 2005
AbstractIn the present work we analyzed the distribution of retinal ganglion cells (RGCs) in the pig retina. RGCs were retrogradely labeled in vivo by injecting Fluoro‐Gold into the optic nerve. RGC density and the distribution of RGCs in terms of soma size were analyzed. Different regions of the porcine retina were identified following analysis of the
Mónica, Garcá   +3 more
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Rodent Retinal Ganglion Cell Cultures

2012
Central neurons lose the ability for axonal regrowth during development and typically do not regenerate their axons following axotomy once they become mature unless given a growth-permissive environment, for example, a peripheral nerve graft. Retinal ganglion cells (RGCs) of the optic nerve represent a highly useful cell model for the study of ...
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'Refracting' a Single Retinal Ganglion Cell

Archives of Ophthalmology, 1971
The response characteristics of retinal ganglion cells to focused and blurred imagery and three interdependent response criteria, measured at the ganglion cell level, are used for the neurophysiological estimate of refractive error.
R M, Hill, H, Ikeda
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Concerted Signaling by Retinal Ganglion Cells

Science, 1995
To analyze the rules that govern communication between eye and brain, visual responses were recorded from an intact salamander retina. Parallel observation of many retinal ganglion cells with a microelectrode array showed that nearby neurons often fired synchronously, with spike delays of less than 10 milliseconds.
M, Meister, L, Lagnado, D A, Baylor
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Correlated firing of retinal ganglion cells

Trends in Neurosciences, 1989
Even in the absence of visual stimulation, retinal ganglion cells have a substantial maintained discharge. This maintained discharge is not generated independently within each ganglion cell, because the unstimulated activity of two neighboring ganglion cells can be remarkably correlated.
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Diacylglycerol Signaling in Retinal Ganglion Cells

With impaired retinal ganglion cell (RGC) function and eventual RGC death, there is a heightened risk of experiencing glaucoma-induced blindness or other optic neuropathies. Poor RGC efficiency leads to limited transmission of visual signals between the retina and the brain by RGC axons.
Ishan, Chaplot   +3 more
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Morphological identification and systematic classification of mammalian retinal ganglion cells. I. Rabbit retinal ganglion cells

Journal of Comparative Neurology, 2020
AbstractRetinal ganglion cells (RGCs) convey visual signals to 50 regions of the brain. For reasons of interest and convenience, they constitute an excellent system for the study of brain structure and function. There is general agreement that, absent a complete “parts list,” understanding how the nervous system processes information will remain an ...
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