Results 61 to 70 of about 38,468 (270)
Axial length, myopia progression, and myopic maculopathy in Stickler syndrome
Acta Ophthalmologica, EarlyView.Abstract Purpose We lack knowledge on the potentially progressive nature of and the prevalence of complications to myopia as a characteristic trait of Stickler syndrome. Methods This cross‐sectional study combines ophthalmic examination and medical record data on Danish patients with genetically confirmed Stickler syndrome type 1 (COL2A1) and type 2 ...
Kirstine B. Boysen +4 more
wiley +1 more source
The prechoroidal cleft in neovascular age‐related macular degeneration
Acta Ophthalmologica, EarlyView.Abstract The prechoroidal cleft is a lenticular, hypo‐reflective space on optical coherence tomography imaging, located between a band of fibrovascular material underneath the retinal pigment epithelium (RPE) and Bruch's membrane. It occurs in 8%–22% of neovascular age‐related macular degeneration (nAMD) eyes, most often with macular neovascularization
Niels J. Brouwer +3 more
wiley +1 more source
CellsFunctional cell death pathways are essential for normal ocular vascular development and tissue homeostasis. As our understanding of necrosis-based cell death pathways has expanded, the inclusion of regulated forms, including necroptosis, ferroptosis, and
Yong-Seok Song +10 more
doaj +1 more source
Vitreoretinal complications and surgical outcomes in patients with X‐linked retinoschisis
Acta Ophthalmologica, EarlyView.Abstract Purpose X‐linked retinoschisis (XLRS) is an inherited vitreoretinal disorder characterized by macular retinoschisis. In a subgroup of patients, peripheral retinoschisis can occur, potentially leading to complications such as vitreous haemorrhage (VH) and retinal detachment (RD).
Jonathan Hensman +11 more
wiley +1 more source
Retinal neovascularization and its therapeutic agents
Folia Pharmacologica Japonica, 2010 増殖糖尿病網膜症（proliferative diabetic retinopathy : PDR），未熟児網膜症，網膜静脈閉塞症および加齢黄斑変性症（age-related macular degen-eration : AMD）などの後眼部疾患は，網膜における病的な血管新生により惹起される疾患で不可逆的な視野欠損や失明を引き起こす．しかし，これまでこれら疾患に対する有効な治療薬はなく，その網膜血管新生を阻害する薬剤の開発が試みられてきた．近年，強力な血管新生促進因子として血管内皮細胞増殖因子（vascular endothelial growth factor : VEGF）が同定され，さらにPDRおよびAMDの発症に深く関与していることが明らかにされ ...
Shinsuke, Nakamura +2 more
openaire +3 more sources
Acta Ophthalmologica, EarlyView.Abstract Purpose To evaluate long‐term outcomes of anti‐VEGF therapy for nAMD using the Polish Retinal Therapeutic Program Monitoring Registry. Methods The cohort consisted of 63 840 eyes with nAMD qualified for treatment from 2016 to 2022, with follow‐up through 31 October 2023. Long‐term follow‐up (>5 years) was conducted for 7631 eyes.
Sławomir Teper +9 more
wiley +1 more source
PLoS ONE, 2012 Neovascularization associated with diabetic retinopathy (DR) and other ocular disorders is a leading cause of visual impairment and adult-onset blindness. Currently available treatments are merely palliative and offer temporary solutions. Here, we tested
Virginia Haurigot +6 more
doaj +1 more source
PLoS ONE, 2017 Retinal ischemia and pathological angiogenesis cause severe impairment of sight. Oxygen-induced retinopathy (OIR) in young mice is widely used as a model to investigate the underlying pathological mechanisms and develop therapeutic interventions.
Pilar Villacampa +8 more
doaj +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To investigate changes in choroidal and retinal thickness before and during myopia control treatment with orthokeratology lenses (OKL) in myopic children. Methods This was a sub‐study of CONTROL and CONTROL2 studies. The present study was a 2‐year, prospective, single‐group interventional study consisting of a 6‐month pre‐treatment ...
P. O. Hansen, F. Møller, T. M. Jakobsen
wiley +1 more source