Results 71 to 80 of about 38,468 (270)

Risk factors for the development of subretinal fluid in the fellow eyes of patients with chronic central serous chorioretinopathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess the risk of subretinal fluid (SRF) development in the fellow eye of chronic central serous chorioretinopathy (cCSC) patients with unilateral SRF at baseline. Methods Medical records of 334 presumed cCSC patients were retrospectively reviewed.
Helena M. A. Feenstra, Tahir Cakar, Joost Brinks, Camiel J. F. Boon, Elon H. C. van Dijk   +4 more
wiley   +1 more source

Long‐term follow‐up of chronic central serous chorioretinopathy patients receiving oral eplerenone and half‐dose photodynamic therapy in the SPECTRA trial: SPECTRA trial report No. 4

Acta Ophthalmologica, EarlyView.
Abstract Purpose Assessing the 24‐month treatment outcome of half‐dose photodynamic therapy (PDT) or oral eplerenone in chronic central serous chorioretinopathy (cCSC). Methods Multicentre randomized clinical trial included cCSC patients from the SPECTRA trial who were randomized to receive half‐dose PDT or oral eplerenone.
Helena M. A. Feenstra, Issam El Mansori, Thomas J. van Rijssen, Roula Tsonaka, Roselie M. H. Diederen, Carel B. Hoyng, Reinier O. Schlingemann, Camiel J. F. Boon, Elon H. C. van Dijk   +8 more
wiley   +1 more source

Absence of TGFβ signaling in retinal microglia induces retinal degeneration and exacerbates choroidal neovascularization

eLife, 2019
Constitutive TGFβ signaling is important in maintaining retinal neurons and blood vessels and is a factor contributing to the risk for age-related macular degeneration (AMD), a retinal disease involving neurodegeneration and microglial activation.
Wenxin Ma, Sean M Silverman, Lian Zhao, Rafael Villasmil, Maria M Campos, Juan Amaral, Wai T Wong   +6 more
doaj   +1 more source

The impact of systemic long‐term medications for the development of age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose Age‐related macular degeneration (AMD) is a leading cause of central vision loss in the elderly; however, the systemic factors that modulate its incidence and progression remain unclear. We sought to determine whether long‐term use of systemic medications, including diabetes and antithrombotic medications, corticosteroids and ...
Hanna Heloterä, Reijo Sund, Toni Rikkonen, Kai Kaarniranta   +3 more
wiley   +1 more source

Targeting Endostatin to Potentially Prevent Retinal Neovascularization Using a Hypoxia-Responsive Muller Glia Cell-Specific Gene Therapy [PDF]

, 2014
Cheryl M. Craft
openalex   +1 more source

The impacts of high refractive errors on self‐reported visual function and visual concern

Acta Ophthalmologica, EarlyView.
Abstract Purpose To examine the association between refractive errors and self‐reported visual function and visual concern, considering self‐perceived present eyesight, concerns about vision, accomplishing less and limitations in daily activities in an eye‐healthy cohort.
Jens Riis Møller, Arevak Saruhanian, Jens Rovelt, Josefine Freiberg, Marcel Reimann, Jeppe Nygård Samuelsen, Christina Eckmann‐Hansen, Miriam Kolko, Nina Jacobsen, FOREVER Consortium   +9 more
wiley   +1 more source

A Challenging Approach: Iris Neovascularization and Vitreous Hemorrhage 40 Years after Treatment of Retinal Giant Tear Detachment

International Medical Case Reports Journal
Ingrid Kreissig,1 Stefan Mennel2 1Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University Heidelberg, Mannheim, Germany; 2Department of Ophthalmology, Phillips-University Marburg, Marburg, GermanyCorrespondence: Ingrid ...
Kreissig I, Mennel S
doaj  

Fenofibrate Inhibits Cytochrome P450 Epoxygenase 2C Activity to Suppress Pathological Ocular Angiogenesis

EBioMedicine, 2016
Neovascular eye diseases including retinopathy of prematurity, diabetic retinopathy and age-related-macular-degeneration are major causes of blindness.
Yan Gong, Zhuo Shao, Zhongjie Fu, Matthew L. Edin, Ye Sun, Raffael G. Liegl, Zhongxiao Wang, Chi-Hsiu Liu, Samuel B. Burnim, Steven S. Meng, Fred B. Lih, John Paul SanGiovanni, Darryl C. Zeldin, Ann Hellström, Lois E.H. Smith   +14 more
doaj   +1 more source

Circulating angiogenesis‐related biomarkers in sickle cell retinopathy and maculopathy

British Journal of Haematology, EarlyView.
Summary Sickle cell disease (SCD), encompassing genotypes such as HbSS and HbSC, leads to retinal complications such as sickle cell retinopathy (SCR) and maculopathy (SCM) through poorly understood mechanisms. This study explored associations of a panel of circulating angiogenesis‐related factors with SCR and SCM.
Rajani P. Brandsen, Ingeborg Klaassen, Renée de Caluwe, Erfan Nur, Bart J. Biemond, Roselie M. H. Diederen, Reinier O. Schlingemann   +6 more
wiley   +1 more source

Ref-1 redox activity modulates canonical Wnt signaling in endothelial cells

Redox Biology
Ischemic retinopathies, including proliferative diabetic retinopathy (PDR) and retinopathy of prematurity (ROP), are characterized by abnormal retinal neovascularization and can lead to blindness in children and adults.
Gabriella D. Hartman, Kamakshi Sishtla, Eyram K. Kpenu, Mahmut Mijit, Anbukkarasi Muniyandi, Ha-Neul Jo, Harald J. Junge, Aaron Shaw, Daniela Bischof, Sheng Liu, Jun Wan, Mark R. Kelley, Timothy W. Corson   +12 more
doaj   +1 more source