Results 71 to 80 of about 386,190 (246)

Bilateral Hypertensive Retinopathy Complicated with Retinal Neovascularization: Panretinal Photocoagulation or Intravitreal Anti-VEGF Treatment

open access: yesCase Reports in Ophthalmology, 2014
Purpose: To present the case of a patient with bilateral hypertensive retinopathy complicated with retinal neovascularization who received anti-VEGF intravitreal injection in one eye and panretinal photocoagulation (PRP) in the fellow eye.
Odysseas Georgiadis   +4 more
doaj   +1 more source

Neovascularization Detection and Localization in Fundus Images Using Deep Learning

open access: yesSensors, 2021
Proliferative Diabetic Retinopathy (PDR) is a severe retinal disease that threatens diabetic patients. It is characterized by neovascularization in the retina and the optic disk. PDR clinical features contain highly intense retinal neovascularization and
Michael Chi Seng Tang   +3 more
doaj   +1 more source

Quantitative and Qualitative Evaluation of Explainable Deep Learning Methods for Ophthalmic Diagnosis [PDF]

open access: yesarXiv, 2020
Background: The lack of explanations for the decisions made by algorithms such as deep learning has hampered their acceptance by the clinical community despite highly accurate results on multiple problems. Recently, attribution methods have emerged for explaining deep learning models, and they have been tested on medical imaging problems.
arxiv  

A Population-Based Ultra-Widefield Digital Image Grading Study for Age-Related Macular Degeneration-Like Lesions at the Peripheral Retina. [PDF]

open access: yes, 2015
Our understanding of the relevance of peripheral retinal abnormalities to disease in general and in age-related macular degeneration (AMD) in particular is limited by the lack of detailed peripheral imaging studies.
Bird, AC   +6 more
core   +1 more source

Vascular changes in diabetic retinopathy-a longitudinal study in the Nile rat. [PDF]

open access: yes, 2019
Diabetic retinopathy is the most common microvascular complication of diabetes and is a major cause of blindness, but an understanding of the pathogenesis of the disease has been hampered by a lack of accurate animal models. Here, we explore the dynamics
Blodi, Barbara A   +10 more
core  

Diverse roles of macrophages in intraocular neovascular diseases: a review [PDF]

open access: yesInternational Journal of Ophthalmology, 2017
Macrophages are involved in angiogenesis, and might also contribute to the pathogenesis of intraocular neovascular diseases. Recent studies indicated that macrophages exert different functions in the process of intraocular neovascularization, and the ...
Ye-Di Zhou   +5 more
doaj   +1 more source

Fractal Dimension and Retinal Pathology: A Meta-analysis [PDF]

open access: yesarXiv, 2021
Due to the fractal nature of retinal blood vessels, the retinal fractal dimension is a natural parameter for researchers to explore and has garnered interest as a potential diagnostic tool. This review aims to summarize the current scientific evidence regarding the relationship between fractal dimension and retinal pathology and thus assess the ...
arxiv  

The ratio of VEGF/PEDF expression in bone marrow mesenchymal stem cells regulates neovascularization [PDF]

open access: yes, 2011
Angiogenesis, or neovascularization, is a finely balanced process controlled by pro- and anti-angiogenic factors. Vascular endothelial growth factor (VEGF) is a major pro-angiogenic factor, whereas pigment epithelial-derived factor (PEDF) is the most ...
Crawford, Ross, Fan, Wei, Xiao, Yin
core   +2 more sources

Formononetin, an active compound of Astragalus membranaceus (Fisch) Bunge, inhibits hypoxia-induced retinal neovascularization via the HIF-1α/VEGF signaling pathway

open access: yesDrug Design, Development and Therapy, 2016
Background It has been reported that formononetin (FMN), one of the main ingredients from famous traditional Chinese medicine “Huang-qi” (Astragalus membranaceus [Fisch] Bunge) for Qi-tonifying, exhibits the effects of immunomodulation and tumor growth ...
Jianming Wu   +9 more
semanticscholar   +1 more source

Retinal Neovascular Disorders: Mouse Models for Drug Development Studies [PDF]

open access: yes, 2011
Neovascularization is a hallmark of several eye diseases leading to visual impairment, and its epidemiological impact is substantial (Lee et al. 1998). In retinal degenerative disease models, neovascularization is the process by which the choroid and/or ...
Craft, Cheryl M., Yetemian, Rosanne M.
core   +1 more source

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