Results 91 to 100 of about 250,265 (247)

Longitudinal progression of retinal nonperfusion in clinically stable diabetic retinopathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To longitudinally assess and quantify changes in retinal nonperfusion (NP) in clinically stable diabetic retinopathy (DR) using ultra‐widefield fluorescein angiography (UWF‐FA) and optical coherence tomography angiography (OCTA). Methods Fifty‐one eyes from thirty‐three patients were followed for a mean of 15.9 ± 11.4 months.
Stela Vujosevic, Sofia Ginelli, Alessandra Cernuschi, Celeste Limoli, Gabriele Piccoli, Elena Tagliabue, Emanuele Torti, Paolo Nucci, Paolo S. Silva   +8 more
wiley   +1 more source

Concurrent macular neovascularization in shallow irregular retinal pigment epithelium elevation phenotypes in age‐related macular degeneration and chronic central serous chorioretinopathy: A systematic review and meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract This systematic review and meta‐analysis synthesized the reported frequency of concurrent macular neovascularization (MNV) among selected eyes with author‐defined shallow irregular retinal pigment epithelium (RPE) elevations in age‐related macular degeneration (AMD) and chronic central serous chorioretinopathy (CSC).
Mehmet Cem Sabaner, Irem Gunes, Rodrigo Anguita, Elon H. C. van Dijk, Lorenzo Ferro Desideri, Lasse Jørgensen Cehofski, Prithvi Ramtohul, Yousif Subhi   +7 more
wiley   +1 more source

A Challenging Approach: Iris Neovascularization and Vitreous Hemorrhage 40 Years after Treatment of Retinal Giant Tear Detachment

International Medical Case Reports Journal
Ingrid Kreissig,1 Stefan Mennel2 1Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University Heidelberg, Mannheim, Germany; 2Department of Ophthalmology, Phillips-University Marburg, Marburg, GermanyCorrespondence: Ingrid ...
Kreissig I, Mennel S
doaj  

Long-term retinal PEDF overexpression prevents neovascularization in a murine adult model of retinopathy.

PLoS ONE, 2012
Neovascularization associated with diabetic retinopathy (DR) and other ocular disorders is a leading cause of visual impairment and adult-onset blindness. Currently available treatments are merely palliative and offer temporary solutions. Here, we tested
Virginia Haurigot, Pilar Villacampa, Albert Ribera, Assumpcio Bosch, David Ramos, Jesus Ruberte, Fatima Bosch   +6 more
doaj   +1 more source

Accelerated oxygen-induced retinopathy is a reliable model of ischemia-induced retinal neovascularization.

PLoS ONE, 2017
Retinal ischemia and pathological angiogenesis cause severe impairment of sight. Oxygen-induced retinopathy (OIR) in young mice is widely used as a model to investigate the underlying pathological mechanisms and develop therapeutic interventions.
Pilar Villacampa, Katja E Menger, Laura Abelleira, Joana Ribeiro, Yanai Duran, Alexander J Smith, Robin R Ali, Ulrich F Luhmann, James W B Bainbridge   +8 more
doaj   +1 more source

Regional growth kinetics of geographic atrophy in age‐related macular degeneration with and without fovea‐sparing

Acta Ophthalmologica, EarlyView.
Abstract Purpose Fovea‐sparing geographic atrophy (GA) patients retain near‐normal central vision. To better understand GA progression in relation to the fovea, we performed a semi‐automated image analysis of regional atrophy growth in a long‐term GA natural‐history cohort. Methods Prospective‐observational, single‐centre‐study (02/2013–07/2025) at the
Daniel R. Muth, Abinaya P. Venkataraman, Alberto Dominguez‐Vicent, Goran Petrovski, Pete A. Williams, Laurence Quérat, Filippo Locri, Sandrine A. Zweifel, Anders Kvanta   +8 more
wiley   +1 more source

Expanding horizons of intravitreal anti-vascular endothelial growth factor therapy in retinal diseases

Indian Journal of Ophthalmology
Vascular endothelial growth factor (VEGF) plays a central role in the pathogenesis of retinal and choroidal neovascularization, as well as macular edema (ME), in retinal disorders such as diabetic retinopathy, retinal vein occlusion (RVO), and age ...
Shalini Singh, Urvashi Kala, Arjun Bamel, Manisha Agarwal   +3 more
doaj   +1 more source

The mechanism of CCN1-enhanced retinal neovascularization in oxygen-induced retinopathy through PI3K/Akt–VEGF signaling pathway

, 2015
Yu Di,1 Yiou Zhang,2 Hongwei Yang,1 Aiyuan Wang,1 Xiaolong Chen11Department of Ophthalmology, Shengjing Affiliated Hospital of China Medical University, Shenyang, People’s Republic of China; 2Graduate School, China Medical University, Shenyang ...
Yang H, Wang A, Zhang Y, Chen X, Di Y
core  

Intravitreal faricimab in patients with nAMD: French data from the Fight Retinal Blindness! Registry

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess real‐world outcomes of intravitreal faricimab in French patients with neovascular age‐related macular degeneration (nAMD) previously treated with vascular endothelial growth factor (VEGF) inhibitors using data from the Fight Retinal Blindness! (FRB!) Registry.
Eloi Debourdeau, Déborah Harboun, Pierre‐Henry Gabrielle, Yohei Hashimoto, Chloe Chamard, Frederic Michon, Benjamin Wolff, Héloïse Torres‐Villaros, Audrey Giocanti‐Auregan, Mark Gillies, Catherine Creuzot–Garcher, Vincent Daien   +11 more
wiley   +1 more source

Higher plasma vitamin D levels are not causally associated with less age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose Higher levels of plasma 25‐hydroxyvitamin D have been associated with a lower risk of age‐related macular degeneration (AMD). We investigated observational and potential causal associations of plasma 25‐hydroxyvitamin D with the risk of AMD in two large contemporary population‐based prospective studies and a genetic case–control ...
Sabina O. Beheshti, Michael Larsen, Børge G. Nordestgaard, Shoaib Afzal   +3 more
wiley   +1 more source