Results 111 to 120 of about 250,265 (247)

Novel insights into retinal neovascularization secondary to central serous chorioretinopathy using 3D optical coherence tomography angiography

, 2020
PurposeTo describe the clinical presentation and novel anatomical features of a patient with chronic central serous chorioretinopathy (CSCR) complicated by retinal neovascularization (RNV).ObservationsA 48 year-old patient with a long-standing history of
Stahl, Andreas, Agostini, Hansjürgen, Neß, Thomas, Wolf, Julian, Scholl, Hendrik, Lange, Clemens, Maloca, Peter M., Gruber, Markus, Lange C, Gruber M, Agostini H, Maloca P, Scholl H, Ness T, Wolf J, Stahl A   +15 more
core   +1 more source

USP25 promotes ferroptosis in diabetic retinopathy by deubiquitinating p53 and suppressing the GPX4/SLC7A11 axis

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Objective To explore the expression of the deubiquitinase (DUB) USP25 in diabetic retinopathy (DR) and its mechanistic role in regulating ferroptosis. Methods Bioinformatics was used to screen for DR‐related DUB candidate genes. USP25 expression was validated in a streptozotocin‐induced diabetic mouse model and high glucose (HG)‐treated ARPE ...
Yanjun Gao, Wenjing Zhao, Qiannan Chai, Cunxi Ye   +3 more
wiley   +1 more source

Reconstruction of deep and perforating corneal defects in dogs—A review (Part I/III): Autogenous ocular tissues, donor tissues, and corneal clarity scoring

Veterinary Ophthalmology, Volume 28, Issue 2, Page 519-531, March 2025.
Abstract Corneal reconstruction is a key part of veterinary ophthalmic practice and numerous reconstructive techniques have been described for use in small animals in the peer‐reviewed veterinary literature written in English. Despite the evidence accrued over the last six decades in over 40 clinical articles and numerous other publications on ocular ...
Rick F. Sanchez, Eric C. Ledbetter, Marta Leiva   +2 more
wiley   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Platelet Factor 4: A Novel Therapeutic Inhibitor for Experimental Neovascular Age-Related Macular Degeneration

Frontiers in Bioscience-Landmark
Background: Platelet factor 4 (PF4/CXCL4) is a chemokine with reported anti-angiogenic and immunomodulatory properties; however, the role of PF4 in neovascular age-related macular degeneration (nAMD) remains unclear.
Xiubin Ke, Shuqi Liang, Tianhao Qu, Shenyu Li, Ji Lei, Han Han, Yingying Guo, Man Xing, Xiaohong Wang, Shikun He, Mengyu Liao, Dongming Zhou, Hua Yan   +12 more
doaj   +1 more source

In Vivo Partial Cell Reprogramming With Yamanaka Factors Reduced Ischemic Brain Damage in Aging Mice

Aging Cell, Volume 25, Issue 11, November 2026.
Short‐term cyclic partial reprogramming with Yamanaka factors protects aged mice from ischemic brain injury, preserving cognitive function, myelin integrity, and neuronal density, supporting partial reprogramming as a promising neuroprotective intervention in aging.
Paula R. Mallavibarrena, Gerardo Martín‐López, Jorge Rodríguez‐Morales, Jesús Ávila, Félix Hernández, María José Pérez‐Álvarez   +5 more
wiley   +1 more source

Pericyte Expression of VEGF-A Minimally Impacts Ocular Vascular Development and Neovascularization

Cells
Pericytes produce vascular endothelial growth factor-A (VEGF-A; hereafter referred to as VEGF). VEGF inhibits pericyte proliferation and migration through enhanced VEGFR2 and PDGFRβ heterodimerization.
Yong-Seok Song, Shoujian Wang, Samay Inampudi, Hope Risa, Christine M. Sorenson, Nader Sheibani   +5 more
doaj   +1 more source

Angiographic results of retinal-retinal anastomosis and retinal-choroidal anastomosis after treatments in eyes with retinal angiomatous proliferation

, 2012
Masaaki Saito,1 Tomohiro Iida,1,2 Mariko Kano,1 Kanako Itagaki11Department of Ophthalmology, Fukushima Medical University School of Medicine, Fukushima, 2Department of Ophthalmology, Tokyo Women's Medical University School of Medicine, Tokyo ...
Kano M, Iida T, Saito M, Itagaki K
core  

The impacts of high refractive errors on self‐reported visual function and visual concern

Acta Ophthalmologica, Volume 104, Issue 7, Page 780-788, November 2026.
Abstract Purpose To examine the association between refractive errors and self‐reported visual function and visual concern, considering self‐perceived present eyesight, concerns about vision, accomplishing less and limitations in daily activities in an eye‐healthy cohort.
Jens Riis Møller, Arevak Saruhanian, Jens Rovelt, Josefine Freiberg, Marcel Reimann, Jeppe Nygård Samuelsen, Christina Eckmann‐Hansen, Miriam Kolko, Nina Jacobsen, FOREVER Consortium   +9 more
wiley   +1 more source

Human Apolipoprotein(a) Kringle V Inhibits Ischemia-Induced Retinal Neovascularization via Suppression of Fibronectin-Mediated Angieogenesis

, 2012
Retinal neovascularization is observed in progression of diabetic retinopathy. New vessels grow into the vitreous cavity in proliferative diabetic retinopathy, resulting in traction retinal detachment and vitreous hemorrhage. To overcome the catastrophic
Yu, Young Suk, Kim, Jeong Hun, Kim, Jin Hyoung, Ahn, Jin-Hyung, Jo, Dong Hyun, Chang, Soo-Ik, Yoon, Yeup, Hwang, Yu Kyeong, Kang, Doug-Ku, Lim, Yangmi   +9 more
core   +1 more source