Results 101 to 110 of about 625,953 (241)

Clinical manifestations of dual‐gene variants in retinitis pigmentosa

Acta Ophthalmologica, EarlyView.
Abstract Purpose Retinitis pigmentosa (RP) is an inherited retinal disease (IRD), whereby each affected individual typically harbours pathogenic variants in a single causative gene, yet the disorder exhibits marked genetic heterogeneity, with more than 100 genes reported to underlie RP.
Lasse Wolfram, Jan‐Philipp Bodenbender, David A. Merle, Milda Reith, Anton Sonntag, Krunoslav Stingl, Tobias B. Haack, Theresia Zuleger, Bernd Wissinger, Laura Kühlewein, Katarina Stingl, Susanne Kohl   +11 more
wiley   +1 more source

Wyburn‐Mason Syndrome: A Case Report

The Kaohsiung Journal of Medical Sciences, EarlyView.
Yu‐Wen Wang, Chen‐Lu Pei, Jian‐Yang Gong   +2 more
wiley   +1 more source

Retinal dystrophies simulating geographic atrophy: A diagnostic challenge

Acta Ophthalmologica, EarlyView.
Abstract Geographic atrophy (GA) is the chronic loss of retinal pigment epithelium, photoreceptors and choriocapillaris, marking the dry late stage of age‐related macular degeneration (AMD). GA prevalence is expected to rise in the upcoming decades. Advanced GA leads to central scotomas, reducing visual acuity and quality of life, potentially resulting
Johanna M. Colijn, Frank G. Holz, Jeroen Pas, Carel Hoyng   +3 more
wiley   +1 more source

Hypoxia-Induced Retinal Neovascularization in Zebrafish Embryos: A Potential Model of Retinopathy of Prematurity

PLoS ONE, 2015
Retinopathy of prematurity, formerly known as a retrolental fibroplasia, is a leading cause of infantile blindness worldwide. Retinopathy of prematurity is caused by the failure of central retinal vessels to reach the retinal periphery, creating a ...
Yu-Ching Wu, Chao-Yuan Chang, A. Kao, Brian Hsi, Shwu‐Huey Lee, Yau-Hung Chen, I. Wang   +6 more
semanticscholar   +1 more source

Genome‐wide association and interaction analysis for proliferative retinopathy in adults with type 2 diabetes born during famine: The DOLCE study in Ukraine

Acta Ophthalmologica, EarlyView.
Abstract Purpose Proliferative diabetic retinopathy (PDR) is one of the leading causes of blindness in working‐age adults. We have previously shown that the risk of PDR is significantly elevated in individuals with intrauterine exposure to famine. However, the genetic mechanisms mediating this association remain unknown.
Olena Fedotkina, Most Champa Begum, Xuan Tung Trinh, Turkuler Özgumus, Mikael Åkerlund, Peter Nilsson, Leticia Maria Spindola, Valeriya Lyssenko   +7 more
wiley   +1 more source

Retinal ischemia with neovascularization in cisplatin related retinal toxicity

, 2006
PURPOSE: To report a case of macular ischemia and retinal neovascularization in a patient who received cisplatin related ...
Sahu, Anjana, Kwan, Anthony S.L., Palexes, George   +2 more
core   +1 more source

Supplementary Material for: Ocular Syphilis with Retinal and Disc Neovascularization Treated with Bevacizumab: A Case Report

, 2023
We report the findings observed in a young woman with ocular syphilis complicated with retinal and disc neovascularization successfully treated with intravitreal bevacizumab.
Comastri L. (16473012), Iribarren G. (16473021), Bar D. (16473018), Heredia M. (16473015), Schlaen A. (16473024)   +4 more
core   +1 more source

MYDGF promotes pathological and physiological retinal angiogenesis via the Gαi1/3-Gab1-Akt-mTOR signaling

Nature Communications
Retinal neovascularization (RNV) is a potential vision-threatening process characterized by the abnormal growth of retinal vessels. Despite its clinical prevalence, the precise mechanisms governing RNV initiation and progression remain incompletely ...
Ke-ran Li, Ping-ping Fu, Wen Bai, Chao-wen Bai, Yitian Yang, Le Liu, Jin-long Chai, Yujia Yao, Dan Huang, Zhi-qing Zhang, Qin Jiang, Zhou-rui Ma, Yu Feng, Jin Yao, Cong Cao   +14 more
doaj   +1 more source

Childhood ocular safety after postnatal exposure to topical dexamethasone during retinopathy of prematurity screening

Acta Ophthalmologica, EarlyView.
Abstract Purpose Dexamethasone eye drops are being introduced off‐label to prevent progression of severe retinopathy of prematurity (ROP). We evaluated ophthalmologic outcomes in early childhood after postnatal topical dexamethasone exposure in pre‐term infants at a standardized follow‐up examination.
Mariya Petrishka‐Lozenska, Anders K. Nilsson, Ann Hellström, Pia Lundgren   +3 more
wiley   +1 more source

Macular telangiectasia type 2 genetic risk variants associated with clinical characteristics in the Slovenian cohort

Acta Ophthalmologica, EarlyView.
Abstract Purpose Early diagnosis of macular telangiectasia type 2 (MacTel) remains challenging, and the contribution of genetic variation to its clinical heterogeneity is unclear. This study investigated associations between MacTel risk variants and clinical characteristics in a Slovenian cohort.
Ajda Kunčič, Nataša Debeljak, Petra Hudler, Janez Smerkolj, Mojca Urbančič   +4 more
wiley   +1 more source