Results 121 to 130 of about 41,612 (247)

Common Ophthalmic Conditions in Popular Dog Breeds in Japan: Insights From a Survey of 105 Veterinarians Practicing Ophthalmology

Veterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Objective To identify commonly presented dog breeds and potentially heritable ophthalmic diseases encountered by veterinarians practicing ophthalmology in Japan. Methods A survey was distributed through the Japanese Society of Comparative and Veterinary Ophthalmology.
Victoria Caballero, Arisu Kobayashi, Yasuyoshi Umeda, Susumu Hirashima, Yuichiro Muramatsu, Mitsuharu Ota, Makoto Yamashita, Yukako Kobayashi, Keiko Miyadera   +8 more
wiley   +1 more source

Pericyte Expression of VEGF-A Minimally Impacts Ocular Vascular Development and Neovascularization

Cells
Pericytes produce vascular endothelial growth factor-A (VEGF-A; hereafter referred to as VEGF). VEGF inhibits pericyte proliferation and migration through enhanced VEGFR2 and PDGFRβ heterodimerization.
Yong-Seok Song, Shoujian Wang, Samay Inampudi, Hope Risa, Christine M. Sorenson, Nader Sheibani   +5 more
doaj   +1 more source

Optimized Deep Learning Framework for Diabetic Retinopathy Based on Systematic Multi‐Stage Transfer Learning and Predictive Risk Stratification

Applied AI Letters, Volume 7, Issue 2, June 2026.
A multi‐stage transfer learning framework systematically optimizes CNN architectures for diabetic retinopathy detection and risk stratification from fundus images. EfficientNetB7 achieves 96% accuracy while a survival‐inspired model generates continuous risk scores aligned with DR severity for clinically meaningful patient risk assessment.
Mujidat Jibrin, Abdsamad Benkrid
wiley   +1 more source

Retinal vein occlusion: An eye on VEGF

, 2015
Retinal vein occlusion (RVO) is a leading cause of visual impairment across the globe, being the second most common vascular disease affecting the eye and threatening vision.
Awawda, Muhammad
core  

MicroRNA-143 plays a protective role in ischemia-induced retinal neovascularization

, 2019
Retinal neovascularization is a severe complication of proliferative diabetic retinopathy. MicroRNAs (miRNAs) are master regulators of gene expression that play important roles in retinal neovascularization.
Bui, BV, Tu, L, Prea, SM, Singh, V, Li, F, Liu, G-S, He, Z, Wang, J-H, Hewitt, AW, van Wijngaarden, P, Chen, J, Riaz, M, Ling, D, Dusting, GJ   +13 more
core   +1 more source

Crosstalk between endoplasmic reticulum stress and mitochondrial homeostasis: A new perspective on ophthalmic disease treatment

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
The graphical abstract follows a top‐to‐bottom flow: stressors → ER–mitochondria crosstalk → ophthalmic diseases. The central panel highlights three core mitochondria‐associated membrane function axes, color‐coded as follows: light yellow for Ca2+ homeostasis, light blue for mitochondrial dynamics, and light red for mitophagy.
Luyang Jiang, Gongsang Cuomu, Sang Jijia, Yumei Yang, Jufen Liu, Yumin Tao   +5 more
wiley   +1 more source

Platelet Factor 4: A Novel Therapeutic Inhibitor for Experimental Neovascular Age-Related Macular Degeneration

Frontiers in Bioscience-Landmark
Background: Platelet factor 4 (PF4/CXCL4) is a chemokine with reported anti-angiogenic and immunomodulatory properties; however, the role of PF4 in neovascular age-related macular degeneration (nAMD) remains unclear.
Xiubin Ke, Shuqi Liang, Tianhao Qu, Shenyu Li, Ji Lei, Han Han, Yingying Guo, Man Xing, Xiaohong Wang, Shikun He, Mengyu Liao, Dongming Zhou, Hua Yan   +12 more
doaj   +1 more source

DualPath‐DRNet: A Self‐Annotating Dual‐Path Networks for End‐To‐End Diabetic Retinopathy Diagnosis

Engineering Reports, Volume 8, Issue 6, June 2026.
DualPath‐DRNet for automated diabetic retinopathy diagnosis and grading. ABSTRACT One of the challenges in detecting Diabetic Retinopathy (DR) is the detection of subtle early‐stage microaneurysms. DualPath‐DRNet is an end‐to‐end deep learning pipeline for 5‐class DR prediction. The novelty of this method lies in combining lesion detection using YOLOv8,
Ankur Chaudhary, Neetu Faujdar, Ghanshyam Singh   +2 more
wiley   +1 more source

Infliximab for the Treatment of Posterior Uveitis with Retinal Neovascularization in Behçet Disease

, 2004
Purpose To report a case of posterior uveitis with retinal neovascularization in a patient with Behçet disease treated with infliximab. Methods A 50-year-old man with a history of recurrent relapses of ocular inflammation despite immunosuppressive ...
B. Pieri, M.L. Barbera, U. Menchini, F. Giansanti, G. Virgili, L. Emmi   +5 more
core   +1 more source

Feasibility of In Vivo Retinal Flavoprotein Autofluorescence Imaging in a Magnetic‐Bead‐Induced Rodent Glaucoma Model

Journal of Biophotonics, Volume 19, Issue 6, June 2026.
A scanning laser ophthalmoscope, integrated with a real‐time optical coherence tomography (OCT) alignment monitor, detected flavoprotein fluorescence (FPF) signals associated with mitochondrial dysfunction in a rodent glaucoma model. Under 450‐nm excitation, experimental eyes showed spatially inhomogeneous signals that were absent under 505‐nm ...
Eun Ji Lee, Jiwon Kang, Jung‐Ho Chung, Kyoung Min Lee, Yu Jin Roh, Dong Kyun Han   +5 more
wiley   +1 more source