The retina is a part of the central nervous system, has remarkably high energy demands that require efficient retinal metabolism. Dysregulation of retinal metabolism disrupts energy supply and redox balance, leading to the pathogenesis of diverse retinal diseases. Riboflavin and its cofactors, flavin mononucleotide (FMN) and flavin adenine dinucleotide
Xue Zhao +4 more
wiley +1 more source
Protective Effect of Curcumin in Oxidative Stress-Induced Injury on Retinal Pigment Epithelial Cells. [PDF]
Yu HS, Cho H, Shin YU, Hong EH, Koh SH.
europepmc +1 more source
PEBP1 Regulates Ferroptosis in Acute Glaucoma: Targeted Therapy Using Engineered Exosomes
General schematic diagram of Spatial and Single‐Cell Transcriptomics Identifies PEBP1 as a Ferroptosis Mediator in Glaucoma: Targeted Intervention by Engineered Stem Cell Exosomes. ABSTRACT Glaucoma is the leading cause of irreversible blindness worldwide, primarily driven by the progressive loss of retinal ganglion cells (RGCs) under pathological high
Yijia Huang +13 more
wiley +1 more source
Gypenosides mitigate acrylamide-induced oxidative stress, inflammation and lipid metabolic dysregulation in retinal pigment epithelial cells and in zebrafish embryos. [PDF]
Tchiveleketea GM +5 more
europepmc +1 more source
Therapeutic effects of nicotinamide mononucleotide and Indian gooseberry in oxidative stress and inflammation-induced damage on human retinal pigment epithelial cells: A pilot study. [PDF]
Lee D, Nahar JS, Kim S, Lim SS.
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Vitamin A Modulates AHR Signaling and Restricts Zika Virus Replication in Human Retinal Pigment Epithelial Cells: Insights from Molecular Modeling and Antiviral Assays. [PDF]
Marquez AB +7 more
europepmc +1 more source
Effect of dopamine on TGF-β2 secretion by human retinal pigment epithelial cells and the underlying mechanism. [PDF]
Fan J +6 more
europepmc +1 more source
Role of Endogenous Galectin-3 on Cell Biology of Immortalized Retinal Pigment Epithelial Cells In Vitro. [PDF]
Liesenhoff C +7 more
europepmc +1 more source
CRX is an intrinsic suppressor of epithelial‒mesenchymal transition in retinal pigment epithelial cells: a promising therapeutic avenue for subretinal fibrosis. [PDF]
Li D +14 more
europepmc +1 more source
Maresin 1 activates autophagy through SIRT1/PPAR-γ signaling to mitigate high glucose-induced pyroptosis in human retinal pigment epithelial cells. [PDF]
Zhang J +5 more
europepmc +1 more source

