Results 161 to 170 of about 34,005 (206)

Phototoxicity of chlorpromazine on retinal pigment epithelial cells

Current Eye Research, 1988
As it is known that chlorpromazine (CPZ) can bind to melanins as well as cause ocular phototoxicity, we investigated the cytotoxic effects of UV-visible irradiation of melanotic and amelanotic retinal pigment epithelial (RPE) cells in the presence of CPZ.
S, Persad, I A, Menon, P K, Basu, F, Carre   +3 more
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Primary Culture of Porcine Retinal Pigment Epithelial Cells

Journal of Visualized Experiments, 2022
The retinal pigment epithelium (RPE) is a monolayer of polarized pigmented epithelial cells, located between the choroid and neuroretina in the retina. Multiple functions, including phagocytosis, nutrient/metabolite transportation, vitamin A metabolism, etc., are conducted by the RPE on a daily basis.
Feng, Wen, Yanzi, Wang, Danxue, He, Chunyan, Liao, Weijie, Ouyang, Zuguo, Liu, Wei, Li, Yi, Liao   +7 more
openaire   +2 more sources

TISSUE CULTURE OF THE RETINAL PIGMENT EPITHELIAL CELLS

Acta Ophthalmologica, 1978
Pure culture of the retinal pigment epithelial (RPE) cells of the chick embryo was carried out and the morphological characteristics of each developmental stage were observed under light microscope and transmission and scanning electron microscopes.Immature cells had a few, short processes on the apical surface and a few melanin granules in the ...
M, Hayashi, K, Asayama, S, Ueno
openaire   +2 more sources

Involvement of calcium in retinal pigment epithelial cell proliferation and pigmentation

Current Eye Research, 1998
The aim of this study is to explore the role of intracellular calcium in the mechanism of co-regulation of retinal pigment epithelial cells (RPE) by vitreous fluid and platelet mitogens, in order to evaluate the use of calcium modulating drugs in preventing RPE cell proliferation and contraction of fibrocellular membranes.Monolayers of human RPE cells ...
L, Smith-Thomas, J W, Haycock, R, Metcalfe, M, Boulton, S, Ellis, I G, Rennie, P S, Richardson, I, Palmer, M A, Parsons, S, Mac Neil   +9 more
openaire   +2 more sources

Rat retinal progenitor cells and a retinal pigment epithelial factor

Developmental Brain Research, 2001
Retinal progenitor cells were isolated from explants of neonatal rat retinas and characterized by transmission electron microscopy and reverse transcriptase-polymerase chain reaction and by their response to an isolated retinal pigment epithelial cell cell factor.
H J, Sheedlo, A M, Brun-Zinkernagel, L X, Oakford, R S, Roque   +3 more
openaire   +2 more sources

Effects of ascorbic acid on retinal pigment epithelial cells

Current Eye Research, 2001
Evaluation of effects of ascorbic acid on cell characteristics of dedifferentiated porcine retinal pigment epithelial (pRPE) cells.pRPE cells were incubated in vitro with increasing concentrations of ascorbic acid (0.25-1.5 mMol). Cell proliferation was assayed by measuring the incorporation of 5-bromo-2'-deoxy-uridine (BrdU) into cellular DNA ...
J A, Böhmer, B, Sellhaus, N F, Schrage
openaire   +2 more sources

Mechanisms Involved in Retinal Pigment Epithelial Cell Chemotaxis

Archives of Ophthalmology, 1986
Retinal pigment epithelial (RPE) cell chemotaxis may play an important role in proliferative vitreoretinopathy (PVR). Fibronectin and platelet-derived growth factor are chemoattractants for RPE cells. In this study, we used these chemoattractants to examine mechanisms involved in RPE cell chemotaxis.
P A, Campochiaro, B M, Glaser
openaire   +2 more sources

The cytoskeleton of chick retinal pigment epithelial cells in situ

Cell and Tissue Research, 1987
Gelatin-coated slides were used to obtain en face preparations of retinal pigment epithelium (RPE) from 6- to 21-day-old chick embryos in order to study the distribution of F-actin in microfilaments (MF) and the MF-associated proteins, myosin, tropomyosin, alpha-actinin and vinculin in situ at different stages of development by fluorescence microscopy.
K, Turksen, V I, Kalnins
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Xenotransplantation of Retinal Pigment Epithelial Cells Into RCS Rats

Japanese Journal of Ophthalmology, 2002
Successful engraftment of retinal pigment epithelial cells (RPE) to treat RPE-related retinopathy will depend, at least in part, on controlling the immune response. In order to understand this process we evaluated the fate of RPE xenografts in the subretinal space, anterior chamber, and subcutis of nonimmunosuppressed Royal College of Surgeons rats ...
Salvatore, Grisanti, Peter, Szurman, Jens, Jordan, Norbert, Kociok, Karl Ulrich, Bartz-Schmidt, Klaus, Heimann   +5 more
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Antioxidant Properties of Melanin in Retinal Pigment Epithelial Cells

Photochemistry and Photobiology, 2006
ABSTRACTThe retinal pigment epithelium (RPE) is a monolayer of highly pigmented cells lining the inner aspect of Bruch's membrane. This pigmentation is due to eumelanin and a possible antioxidant role of melanin is reported here. The photo‐oxidation of A2E, a constituent of RPE lipofnscin, leads to the sequential addition of up to nine oxygen atoms and/
Z, Wang, J, Dillon, E R, Gaillard
openaire   +2 more sources