Results 141 to 150 of about 91,701 (297)

Retinoic Acid Signalling Regulates Zebrafish Tooth Germ Repair Following Injury

open access: yesCell Proliferation, EarlyView.
Retinoic acid signalling may regulate the repair processes in a tooth germ injury model using Tg(scpp5:Dendra2‐NTR) zebrafish and the nitroreductase (NTR)/metronidazole (MTZ) system. ABSTRACT Although the role of retinoic acid (RA) signalling in odontogenesis is well established, its involvement in the repair of injured tooth germs remains unclear.
Qiqi Liu   +4 more
wiley   +1 more source

The Challenge of the Retinal Pigment Epithelium [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1974
openaire   +2 more sources

Genome-wide screening of mouse knockouts reveals novel genes required for normal integumentary and oculocutaneous structure and function. [PDF]

open access: yes, 2019
Oculocutaneous syndromes are often due to mutations in single genes. In some cases, mouse models for these diseases exist in spontaneously occurring mutations, or in mice resulting from forward mutatagenesis screens.
Adissu, Hibret   +15 more
core  

Next‐Generation Strategies for Neural Repair and Regeneration: Neural Organoid Transplantation in the CNS

open access: yesCell Proliferation, EarlyView.
Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang   +8 more
wiley   +1 more source

Cyclic AMP modulation of ion transport across frog retinal pigment epithelium. Measurements in the short-circuit state. [PDF]

open access: yes, 1984
In the frog retinal pigment epithelium (RPE), the cellular levels of cyclic AMP (cAMP) were measured in control conditions and after treatment with substances that are known to inhibit phosphodiesterase (PDE) activity (isobutyl-1-methylxanthine, SQ65442)
Farber, D, Miller, S
core  

The technical and practical implementation of fundus photography in equids

open access: yesEquine Veterinary Education, EarlyView.
Summary Background Fundus photography is an important diagnostic tool in human and veterinary medicine. Advances in research are increasing its accessibility in human medicine. However, there is a lack of studies on modern fundus photography in animals, particularly in horses. Objectives To assess the use of a portable fundus camera developed for human
I. Vierling, B. Wollanke, V. Franzen
wiley   +1 more source

Evaluating choroidal thickness in diabetic retinopathy

open access: yesClinical Ophthalmology, 2014
Chee Yee Chan,1 Thanos D Papakostas,2 Demetrios Vavvas2 1Department of Ophthalmology, 2Retina Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USAWe read with interest the article by Unsal et al1 and congratulate them ...
Chan CY, Papakostas TD, Vavvas DG
doaj  

Direct delivery of Cas9 or base editor protein and guide RNA complex enables genome editing in the retina

open access: yesMolecular Therapy: Nucleic Acids
Genome editing by CRISPR-Cas holds promise for the treatment of retinal dystrophies. For therapeutic gene editing, transient delivery of CRISPR-Cas9 is preferable to viral delivery which leads to long-term expression with potential adverse consequences ...
Juliette Pulman   +16 more
doaj   +1 more source

Induction of dark-adaptive retinomotor movement (cell elongation) in teleost retinal cones by cyclic adenosine 3,5-monophosphate. [PDF]

open access: yes, 1982
In the teleost retina, the photoreceptors and retinal pigment epithelium (RPE) undergo extensive movements (called retinomotor movements) in response to changes in light conditions and to an endogenous circadian rhythm.
BURNSIDE, Beth   +3 more
core  

Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function [PDF]

open access: yes, 2018
Visual function in vertebrates critically depends on the continuous regeneration of visual pigments in rod and cone photoreceptors. RPE65 is a well-established retinoid isomerase in the pigment epithelium that regenerates rhodopsin during the rod visual ...
Angueyra, Juan M   +11 more
core   +1 more source

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