Results 151 to 160 of about 66,016 (272)

Moutan Cortex Extract Mediates Diabetic Retinopathy by Blocking the ROS‑Triggered HIF‐1α/VEGF Axis in Retinal Pigment Epithelial Cells

eFood, Volume 7, Issue 4, August 2026.
Schematic diagram of the mechanism by which Moutan Cortex extract (MCE) ameliorates DR. MCE alleviates retinal structural damage and reduces neovascular lesions by downregulating the ROS/HIF‐1α/VEGF signaling axis. ABSTRACT Moutan Cortex is a functional food ingredient with multiple health benefits, but its effects on diabetic retinopathy (DR) remain ...
Mei‐rong Li, Xian‐yi Zhang, Wan‐ying Zhang, Nan Chen, Wei‐wei Lv, Tian‐yu Liu, Xu Guo, Ying‐ying Chen, Meng‐qi Zhang, Shu‐tao Sun, Mu‐xuan Wang, Qi‐dong Ren, Chao Liu, Jin‐yue Sun   +13 more
wiley   +1 more source

Influence of tyrosinase levels on pigment accumulation in the retinal pigment epithelium and on the uncrossed retinal projection

To study the relationship among tyrosinase activity, melanin production, and the routing of retinal ganglion cell (RGC) axons at the optic chiasm, we analysed mice with varying doses of the tyrosinase gene. These include the dark-eyed albino (Tyrc44H), a
Rachel, R. A., Mason, C. A., Beermann, F.   +2 more
core   +1 more source

Differentiating the Clinical and Variant Spectrum of Hardikar Syndrome From Other MED12 ‐Related Developmental Disorders

American Journal of Medical Genetics Part A, Volume 200, Issue 7, Page 1619-1650, July 2026.
ABSTRACT The rare X‐linked female‐restricted Hardikar syndrome (HDKR, OMIM # 301068) is characterized by multiple congenital anomalies including orofacial clefts, gastrointestinal, genitourinary, and cardiac anomalies, but cognitive and neurobehavioral development is rarely impaired.
Tinne Warmoeskerken, Miel Theunis, Kris Van den Bogaert, Koenraad Devriendt, Jeroen Breckpot   +4 more
wiley   +1 more source

Retinal pigment epithelium drives macrophage migration during Toxoplasma gondii infection in vitro [PDF]

Mem Inst Oswaldo Cruz
Nasaré AM, Tedesco RC, Waziry PAF, Pantaleon LP, Ricci EL, Leoni LAB, Fukushima AR, Galisteo Junior AJ.   +7 more
europepmc   +1 more source

Dietary Polyphenols as Natural Modulators of NF‐κB Signaling in Inflammation‐Driven Non‐Communicable Diseases: Focus on Cancer

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Dietary polyphenols and phytochemicals suppress NF‐κB signaling. Mechanistically, by inhibiting IκBα degradation and preventing nuclear translocation of p65/p50 complexes, the polyphenols reduce the expression of pro‐inflammatory and pro‐survival genes, thereby decreasing overall cancer cell survival.
Khuzin Dinislam, Anas Shamsi, Syed Tasqeruddin, Moyad Shahwan   +3 more
wiley   +1 more source

A nonpigmented retinal pigment epithelium adenoma with retinitis pigmentosa:A case report. [PDF]

Am J Ophthalmol Case Rep
Zhu X, Zhu Y, Yang X, Liu H.
europepmc   +1 more source

Bovine Milk–Derived Extracellular Vesicles as Emerging Drug Delivery Platforms: Current Advances, Applications and Challenges

Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.
ABSTRACT Extracellular vesicles (EVs) are nanosized lipid bilayer particles naturally secreted by cells, mediating intercellular communication and transporting diverse bioactive molecules. Among alternative EV sources, bovine milk‐derived EVs (BMEVs) have emerged as promising platforms for drug delivery due to their accessibility, scalability ...
Martina Brattini, Michelle D'Urso, Sofia Mariotto, Elena Butturini   +3 more
wiley   +1 more source

AGE-RELATED RETINAL PIGMENT EPITHELIUM DISEASE: Clinical and Differential Features. [PDF]

Retina
Arrigo A, Aragona E, Antropoli A, Bianco L, Saladino A, Del Fabbro S, Bandello F, Parodi MB.   +7 more
europepmc   +1 more source

ABCA4‐Associated Retinal Degeneration in 8 Families From the Three Provinces of Northeast China: Identification and Characterization of Potentially Novel Variants

Molecular Genetics &Genomic Medicine, Volume 14, Issue 7, July 2026.
This study reports the documented case of ABCA4‐associated early‐onset severe retinal dystrophy in China, broadens the mutational spectrum of ABCA4 in this population, and highlights distinct genotype–phenotype correlations that may inform clinical management and genetic counseling.
Nian Li, Linlin Su, Yue Ren, Ye Liu, Jiayuan Ge, Henan Sun, Zhuoshi Wang   +6 more
wiley   +1 more source

Retinal Pigment Epithelium [PDF]

, 2020
openaire   +1 more source