Results 151 to 160 of about 91,701 (297)

Sodium–glucose cotransporter 2 inhibition and injection burden in mild diabetic macular edema: An exploratory post hoc analysis of the COMET trial

Journal of Diabetes Investigation, EarlyView.
Combining oral sodium‐glucose cotransporter 2 inhibitors with reduced intravitreal injections of anti‐vascular endothelial growth factor showed potential efficacy for mild diabetic macular edema. ABSTRACT Aims To investigate the potential of sodium–glucose cotransporter 2 inhibitors (SGLT2i) as a less invasive treatment option for mild diabetic macular
Yoko Takatsuna, Ryoichi Ishibashi, Masaya Koshizaka, Tomoaki Tatsumi, Takayuki Baba, Shuichi Yamamoto, Koutaro Yokote   +6 more
wiley   +1 more source

Neural modulation of ocular immunity: Exploring a sympathetic‐macrophage neuroimmune link in the human ciliary body

Journal of Anatomy, EarlyView.
Using microscopy and 3D confocal imaging on seven cadaveric eyes, we identified sympathetic nerves closely associated with β₂‐adrenergic receptor‐expressing macrophages in the human ciliary body (CB). These findings suggest a sympathetic‐macrophage neuroimmune link in the CB, potentially influencing ocular inflammation and degeneration, warranting ...
Tanya S. Karakyriakou, Claire Mackaaij, Mark van Zijverden, Hendrik A. Messal, Jeannette Ossewaarde‐van Norel, Ronald L. A. W. Bleys, Cindy G. J. Cleypool   +6 more
wiley   +1 more source

Techniques for subretinal injections in animals

Veterinary Ophthalmology, Volume 28, Issue 2, Page 506-518, March 2025.
Abstract Subretinal injections are not commonly performed during clinical treatment of animals but are frequently used in laboratory animal models to assess therapeutic efficacy and safety of gene and cell therapy products. Veterinary ophthalmologists are often employed to perform the injections in the laboratory animal setting, due to knowledge of ...
Ryan F. Boyd, Simon M. Petersen‐Jones
wiley   +1 more source

Retinal pigment epithelium cholesterol efflux mediated by the 18kDa translocator protein, TSPO, a potential target for treating age-related macular degeneration [PDF]

, 2017
Biswas, Lincoln, Dhillon, Baljean, Graham, Annette, Shu, Xinhua, Zhou, Xinzhi   +4 more
core   +2 more sources

Reconstruction of deep and perforating corneal defects in dogs—A review (Part I/III): Autogenous ocular tissues, donor tissues, and corneal clarity scoring

Veterinary Ophthalmology, Volume 28, Issue 2, Page 519-531, March 2025.
Abstract Corneal reconstruction is a key part of veterinary ophthalmic practice and numerous reconstructive techniques have been described for use in small animals in the peer‐reviewed veterinary literature written in English. Despite the evidence accrued over the last six decades in over 40 clinical articles and numerous other publications on ocular ...
Rick F. Sanchez, Eric C. Ledbetter, Marta Leiva   +2 more
wiley   +1 more source

Subretinal lavage to prevent persistent subretinal fluid after rhegmatogenous retinal detachment surgery : a study of feasibility and safety [PDF]

, 2011
Reyniers, Rudolf, Van Aken, Elisabeth, van Meurs, Jan, Veckeneer, Marc, Wong, David   +4 more
core   +2 more sources

Reconstruction of deep and perforating corneal defects in dogs—A review (Part II/III): Biomaterials and keratoprosthesis

Veterinary Ophthalmology, Volume 28, Issue 2, Page 532-542, March 2025.
Abstract The surgical reconstruction of severe corneal ulcers is a common and crucial component of the clinical practice of veterinary ophthalmology. Numerous surgical techniques are used in dogs for corneal reconstruction, and these techniques may be categorized by the material used to repair the corneal lesion.
Eric C. Ledbetter, Rick F. Sanchez, Marta Leiva Repiso   +2 more
wiley   +1 more source

Unveiling protective mechanisms of wild olive (acebuche) oil in retinal pigment epithelial cells with hypertensive phenotype

The Journal of Physiology, EarlyView.
Abstract figure legend Circulating extracellular vesicles (EVs) derived from acebuche (ACE) oil‐ and extra virgin olive oil (EVOO)‐fed mice modulate nitric oxide (NO) metabolism in the retinal pigment epithelial cell line (ARPE19) with a hypertensive phenotype induced by angiotensin II (AngII).
Álvaro Santana‐Garrido, Claudia Reyes‐Goya, Pablo Espinosa‐Martín, Rosa M. Troya‐Toledo, Helder André, Alfonso Mate, Carmen M. Vázquez   +6 more
wiley   +1 more source

Mitochondrial control of ciliary gene expression and structure in striatal neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen, Alessandro Chioino, Olivia Zanoletti, Albert Quintana, Elisenda Sanz, Carmen Sandi   +5 more
wiley   +1 more source

Crosstalk between endoplasmic reticulum stress and mitochondrial homeostasis: A new perspective on ophthalmic disease treatment

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
The graphical abstract follows a top‐to‐bottom flow: stressors → ER–mitochondria crosstalk → ophthalmic diseases. The central panel highlights three core mitochondria‐associated membrane function axes, color‐coded as follows: light yellow for Ca2+ homeostasis, light blue for mitochondrial dynamics, and light red for mitophagy.
Luyang Jiang, Gongsang Cuomu, Sang Jijia, Yumei Yang, Jufen Liu, Yumin Tao   +5 more
wiley   +1 more source