MFGE8 does not influence chorio-retinal homeostasis or choroidal neovascularization in vivo [PDF]
Purpose: Milk fat globule-epidermal growth factor-factor VIII (MFGE8) is necessary for diurnal outer segment phagocytosis and promotes VEGF-dependent neovascularization.
A Swaroop +52 more
core +15 more sources
Phagocytosis by the Retinal Pigment Epithelium: Recognition, Resolution, Recycling
Tissue-resident phagocytes are responsible for the routine binding, engulfment, and resolution of their meals. Such populations of cells express appropriate surface receptors that are tailored to recognize the phagocytic targets of their niche and ...
Whijin Kwon, S. Freeman
semanticscholar +1 more source
Profound Re-Organization of Cell Surface Proteome in Equine Retinal Pigment Epithelial Cells in Response to In Vitro Culturing [PDF]
The purpose of this study was to characterize the cell surface proteome of native compared to cultured equine retinal pigment epithelium (RPE) cells. The RPE plays an essential role in visual function and represents the outer blood-retinal barrier.
Aisenbrey +54 more
core +3 more sources
Early stages of retinal development depend on Sec13 function [PDF]
Summary ER-to-Golgi transport of proteins destined for the extracellular space or intracellular compartments depends on the COPII vesicle coat and is constitutive in all translationally active cells.
Cavodeassi, Florencia +3 more
core +2 more sources
Retinal pigment epithelium degeneration caused by aggregation of PRPF31 and the role of HSP70 family of proteins [PDF]
Background Mutations in pre-mRNA splicing factor PRPF31 can lead to retinitis pigmentosa (RP). Although the exact disease mechanism remains unknown, it has been hypothesized that haploinsufficiency might be involved in the ...
Aramburu, Ana +13 more
core +2 more sources
Advances in the treatment of rhegmatogenous retinal detachment [PDF]
The pathogenesis of rhegmatogenous retinal detachment depends on three factors, namely, retinal rupture, vitreous liquefaction and traction causing the retina to separate from the pigment epithelium, among which retinal rupture is the most important ...
Li Liao, Xiao-Hua Zhu
doaj +1 more source
Detachment of the pigment epithelium is the separation of the basement membrane of the retinal pigment epithelium from the inner collagen layer of Bruch’s membrane, which occurs in 80 % of cases in patients with neovascular age-related macular ...
E. V. Kozina +4 more
doaj +1 more source
The bisretinoids of retinal pigment epithelium [PDF]
The retina exhibits an inherent autofluorescence that is imaged ophthalmoscopically as fundus autofluorescence. In clinical settings, fundus autofluorescence examination aids in the diagnosis and follow-up of many retinal disorders. Fundus autofluorescence originates from the complex mixture of bisretinoid fluorophores that are amassed by retinal ...
Kazunori Yamamoto +6 more
openaire +3 more sources
Scaffolds for retinal pigment epithelial cell transplantation in age-related macular degeneration
In several retinal degenerative diseases, including age-related macular degeneration, the retinal pigment epithelium, a highly functionalized cell monolayer, becomes dysfunctional.
Corina E White, Ronke M Olabisi
doaj +1 more source
Nel positively regulates the genesis of retinal ganglion cells by promoting their differentiation and survival during development [PDF]
Peer reviewedPublisher ...
Adams JC +67 more
core +1 more source

