Results 91 to 100 of about 19,821 (304)

Diacylglycerol O-acyltransferase type-1 synthesizes retinyl esters in the retina and retinal pigment epithelium.

open access: yesPLoS ONE, 2015
Retinyl esters represent an insoluble storage form of vitamin A and are substrates for the retinoid isomerase (Rpe65) in cells of the retinal pigment epithelium (RPE).
Joanna J Kaylor   +9 more
doaj   +1 more source

Chlorophyll-Derivative Modulation of Rhodopsin Signaling Properties through Evolutionarily Conserved Interaction Pathways

open access: yesFrontiers in Molecular Biosciences, 2017
Retinal is the light-absorbing chromophore that is responsible for the activation of visual pigments and light-driven ion pumps. Evolutionary changes in the intermolecular interactions of the retinal with specific amino acids allow for adaptation of the ...
Kristina N. Woods   +2 more
doaj   +1 more source

Berberine alleviates cell pyroptosis in diabetic retinopathy by regulating AKT1, JUN, and STAT3

open access: yesIbrain, EarlyView.
Berberine alleviates diabetic retinopathy by reducing pyroptosis through AKT1/JUN/STAT3 regulation, as validated in rat models via network pharmacology, molecular docking, and experimental assays. Abstract Berberine (BBR) exerts an effective protection for diabetic retinopathy (DR), but the underlying key molecular mechanism remains unknown; this study
Na Li   +7 more
wiley   +1 more source

Functional characterization of spectral tuning mechanisms in the great bowerbird short-wavelength sensitive visual pigment (SWS1), and the origins of UV/violet vision in passerines and parrots [PDF]

open access: yes, 2013
BackgroundOne of the most striking features of avian vision is the variation in spectral sensitivity of the short wavelength sensitive (SWS1) opsins, which can be divided into two sub-types: violet- and UV- sensitive (VS & UVS).
Chang, Belinda S.W.   +4 more
core   +2 more sources

Bio‐inspired nanophotonics: Structural color, chirality, and resonance metasurfaces

open access: yesInfoMat, EarlyView.
A butterfly‐wing‐inspired anisotropic plasmonic flatband resonant metasurface. Insets, photo of the butterfly, Sasakia charonda, and the SEM image of its wing scale (above); the SEM image of the metasurface (below). Abstract The dazzling colors of butterfly wings and hummingbird feathers are not painted with pigments, but crafted by nature's invisible ...
Weihan Liu, Yao Liang, Din Ping Tsai
wiley   +1 more source

Automated Profiling of Social Behaviors to Assess the Genetic Basis of Evolution of Aggressive Behaviors in Astyanax mexicanus

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Across the animal kingdom, social behaviors such as aggression are critical for survival and reproductive success. While there is significant variation in social behaviors within and between species, the genetic mechanisms underlying natural variation in social behaviors are poorly understood.
Renee Mapa   +5 more
wiley   +1 more source

Tattoo-Associated Uveitis: A Case Series Highlighting Diverse Clinical Presentations and Therapeutic Challenges

open access: yesCase Reports in Ophthalmological Medicine
Tattoo-associated uveitis is a rare inflammatory condition linked to tattooed skin, often presenting as bilateral anterior uveitis with complications such as macular edema and retinal vasculitis.
Sara Isabel Ospina Londoño   +2 more
doaj   +1 more source

Glycemic Control, Animal Protein Intake, and the Risk of Diabetic Retinopathy Progression Among Patients With Type 2 Diabetes

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Effective glycemic control and food consumption play crucial roles in modulating diabetic retinopathy (DR) progression. This observational longitudinal study explored the hemoglobin A1c (HbA1c) and dietary patterns and their associations with the risk and progression of DR among 369 individuals with type 2 diabetes.
Yu‐Ju Wu   +8 more
wiley   +1 more source

Photoenergy transduction in halobacterium halobium [PDF]

open access: yes
The structure and function of a rhodopsin-like pigment bacteriorhodopsin, discovered and isolated from the membranes of the halophile Halobacterium halobium, were studied.
Bogomolni, R. A., Stoeckenius, W.
core   +1 more source

Airway Involvement in Conradi–Hünermann–Happle Syndrome: A Novel Clinical Manifestation

open access: yesThe Laryngoscope, EarlyView.
We report the first documented case of airway involvement in Conradi–Hünermann–Happle syndrome (CDPX2), an X‐linked dominant form of chondrodysplasia punctata caused by pathogenic variants in EBP. A 2‐month‐old female with genetically confirmed CDPX2 developed severe subglottic stenosis and persistent respiratory distress requiring CPAP; cross ...
Enrique G. Villarreal   +3 more
wiley   +1 more source

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