Results 181 to 190 of about 5,449,684 (261)

Precision Medicine in Neurodegeneration with Brain Iron Accumulation (NBIA) Disorders: An Update on Emerging Treatments

Movement Disorders Clinical Practice, Volume 13, Issue 10, Page 2405-2418, October 2026.
Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider, Divyani Garg, Vassilena Iankova, Thomas Klopstock   +3 more
wiley   +1 more source

Integrated Digital Garment Modeling and Monte Carlo Simulation of a Water‐Based Radiation Protection Vest for Spaceflight Radiation Hazards

Space Weather, Volume 24, Issue 10, October 2026.
Abstract As crewed space missions set course for the Moon and beyond, astronauts will experience prolonged exposure to Galactic Cosmic Rays (GCR) and potentially intense Solar Proton Events (SPEs), both of which pose significant short‐ and long‐term health risks.
Sylvain Blunier, Noora Archer, Margot Winters, Agnieszka Jugowicz, Aidan Cowley   +4 more
wiley   +1 more source

A Simple Temperature‐Controlled Method for Preserving Viability in Human Pluripotent Stem Cell‐Derived Retinal Organoids During Shipment

FASEB BioAdvances, Volume 8, Issue 10, October 2026.
A lithium‐free temperature‐controlled shipping system (YOTI) stabilizes physiologic temperatures during overnight transport of mature human iPSC‐derived retinal organoids. Compared to conventional ambient shipping, YOTI reduces temperature fluctuations, preserves retinal lamination, decreases cell death, and maintains rod photoreceptor marker ...
Karen Cusato, Matthew J. Tarchick, Michael Ha, Jessica R. Onyak, Aimee C. Saunders, Joseph A. Brzezinski IV, Jordan M. Renna, M. Natalia Vergara   +7 more
wiley   +1 more source

Long-term safety of human retinal progenitor cell transplantation in retinitis pigmentosa patients. [PDF]

Stem Cell Res Ther, 2017
Liu Y, Chen SJ, Li SY, Qu LH, Meng XH, Wang Y, Xu HW, Liang ZQ, Yin ZQ.   +8 more
europepmc   +1 more source

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

Cell Proliferation, Volume 59, Issue 10, October 2026.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu, Yanan Guo, Kangjian Xiang, Shuyi Wang, Dongchang Xiao, Mengqing Xiang   +5 more
wiley   +1 more source

Rethinking the Oligodendrocyte Progenitor Cell: One Cell, Many Functions

European Journal of Neuroscience, Volume 64, Issue 7, October 2026.
Oligodendrocyte progenitor cells (OPCs) are increasingly recognised as multifunctional CNS cells rather than mere precursors of myelinating oligodendrocytes. Alongside myelination and remyelination, they contribute to myelin and circuit plasticity, circuit regulation, vascular and blood–brain barrier regulation and neuroimmune modulation.
Alerie G. de la Fuente
wiley   +1 more source

Neural Cell Models of Specific Reading Disabilities: Identification of Cellular and Transcriptome Alterations

Genes, Brain and Behavior, Volume 25, Issue 5, October 2026.
Neural cell phenotypes were tested using cells derived from two pairs of siblings strongly discordant for reading—probands with severe RD and their strong‐reader siblings. We observed significant differences in outgrowth in the neurosphere assay using the neural precursor cells (NPCs) derived from the probands compared to cells from their strong‐reader
Cathy L. Barr, Karen G. Wigg, Yu Feng, Kirsten Blokland, Margaret Wilkinson, Elizabeth N. Kerr, Sharon L. Guger, Maureen W. Lovett, Lisa J. Strug, Ruth Oefner, Simone Benassi, Fred H. Gage, Maria C. Marchetto   +12 more
wiley   +1 more source

Maternal protein restriction programs the ageing kidney: Proteomic signatures of early‐life origin renal and metabolic dysfunction

The Journal of Physiology, Volume 604, Issue 20, Page 8636-8661, 15 October 2026.
Abstract figure legend Maternal protein restriction (MPR) induced persistent renal histopathological alterations accompanied by elevated serum creatinine levels. Nephron‐segment proteomic analysis revealed region‐specific molecular dysregulation affecting Bowman's capsule (PARK7, oxidative stress sensor; MSN, cytoskeletal organization), the proximal ...
Marina Pereira Pires, Matheus Naia Fioretto, Marcel Rodrigues Ferreira, Isabelle Tenori Ribeiro, Luísa Annibal Barata, Flávia Alessandra Maciel, Lucas Sobrinho Lemos, Renato Mattos, Luiz Marcos Frediane Portela, Patrick Vieira de Souza, Luisa Correia Gomes, Gustavo Monezzi Cordeiro, Wellerson Rodrigo Scarano, Patrícia Aline Boer, Jose Antonio Rocha Gontijo, Luis Antonio Justulin   +15 more
wiley   +1 more source

Receptor tyrosine kinase signaling in mammalian eye development. [PDF]

Dev Biol
Makrides N, Wu Y, Almonte Y, Zhang X, Tao C.   +4 more
europepmc   +1 more source

Development and Characterization of a Structurally Supportive of Hybrid PLGA Decellularized ECM Biomembrane for Ocular Progenitor Cell Anchorage and Epithelial Repair. [PDF]

Macromol Biosci
Ungaratti AKG, de Lima AP, Santos JA, de Melo PL, Graziani D, da Silva ACG, Silva LAD, Valadares MC.   +7 more
europepmc   +1 more source