Results 161 to 170 of about 5,449,684 (261)

Actuator Transcription Factors Resolve Combinatorial Binding Into Productive Gene Expression

BioEssays, Volume 48, Issue 10, October 2026.
Actuators convert combinatorial transcription factor (TF) binding into productive transcription. Broadly expressed actuators are recruited to enhancers by cooperating lineage‐restricted TFs and mediate transcriptional activation. Two enhancer scenarios: lineage‐specific selector TFs bound to an enhancer alone (light blue) do not activate transcription (
Nicoletta Bobola, Zoulfia Darieva
wiley   +1 more source

Tubgcp3 Is Required for Retinal Progenitor Cell Proliferation During Zebrafish Development. [PDF]

Front Mol Neurosci, 2019
Li G, Jin D, Zhong TP.
europepmc   +1 more source

In Situ Cross-linking Hydrogel as a Vehicle for Retinal Progenitor Cell Transplantation. [PDF]

Cell Transplant, 2019
Park J, Baranov P, Aydin A, Abdelgawad H, Singh D, Niu W, Kurisawa M, Spector M, Young MJ.   +8 more
europepmc   +1 more source

Plagl1 regulates the retinal progenitor cell to Müller glial cell transition. [PDF]

PLoS Genet
Touahri Y, Pak A, David LA, Hanna J, Liu H, Xiao Y, Belfiore L, Ilnytskyy Y, van Oosten E, Tachibana N, Adnani L, Zhao J, Hoffman M, Dixit R, Zinyk D, Guidos CJ, Enzmann V, Bi P, Aubert I, Journot L, Kovalchuk I, Sauvé Y, Biernaskie J, Wang C, Okawa S, Del Sol A, Schuurmans C.   +26 more
europepmc   +1 more source

Insights Into the Role of Platelet Factor 4 in Neurodegenerative Diseases

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
This review summarizes potential functions of platelet factor 4 (PF4) in neurodegenerative diseases (NDs) and discusses its promise as both a biomarker and a therapeutic target. Further elucidation of PF4 signaling pathways may provide new insights into disease mechanisms and uncover novel opportunities for targeted interventions in NDs.
Qi Tian, Yanji Tong, Fang Yu, Xiaoming Hu   +3 more
wiley   +1 more source

Beyond the Heart‐Lung Axis: A Review of the Crosstalk Between the Hemodynamic, Neurohormonal, and Immune Systems in Pulmonary Hypertension

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
Pulmonary hypertension is driven by dynamic crosstalk beyond the physical connection between the heart and lung, involving neurohormonal systems, immune pathways, and peripheral organs. This review highlights how multisystem signaling contributes to disease progression and may reveal new diagnostic and therapeutic targets.
Alejandro A. Vega, Juliet M. Alfaro, David S. Pinto, Maryam Emamimeybodi, Soban Umar   +4 more
wiley   +1 more source

Human Retinal Progenitor Cell (hRPC) Migration in Three-Dimensional (3D) Environments of Varying Stiffness and Composition. [PDF]

J Tissue Eng Regen Med
Zhao P, Kundu J, Blanton D, Rezaeeyazdi M, Oudin MJ, Miller MA, Meyer AS, Bencherif SA, Baranov PY, Young MJ, Carrier RL.   +10 more
europepmc   +1 more source

Molecular and Proteomic Profiling of Human Cerebral Organoid‑Derived Small Extracellular Vesicles

Developmental Neurobiology, Volume 86, Issue 4, October 2026.
ABSTRACT Organoids are self‐organized, in vitro 3D structures derived from progenitor or pluripotent stem cells. During culture, these tissues secrete small extracellular vesicles (sEVs)—functional bioactive molecules—into their microenvironment. Here, we differentiated iPSC‐derived cerebral organoids (COs) under three culture conditions (static ...
Elifsu Polatlı, Burak Kahveci, Çağla Kiser, Nurhan Özlü, Gökhan Karakülah, Şermin Genç, Sinan Güven   +6 more
wiley   +1 more source

Glycolytic flux controls retinal progenitor cell differentiation via regulating Wnt signaling. [PDF]

Elife
Hanna J, Touahri Y, Pak A, Belfiore L, van Oosten E, David LA, Han S, Ilnytskyy Y, Kovalchuk I, Kurrasch D, Okawa S, Del Sol A, Screaton RA, Aubert I, Schuurmans C.   +14 more
europepmc   +1 more source

Temporal Progression of Retinal Progenitor Cell Identity: Implications in Cell Replacement Therapies. [PDF]

Front Neural Circuits, 2017
Javed A, Cayouette M.
europepmc   +1 more source