Results 131 to 140 of about 24,696 (239)
American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1179-1191, June 2026.ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson +1 more
wiley +1 more source
Emerging options for the management of age-related macular degeneration with stem cells
Stem Cells and Cloning: Advances and Applications, 2010 Ingrid Mooney1, James LaMotte21Eye Design, Santa Fe, NM, USA; 2Department of Basic and Visual Science, Southern California College of Optometry, Fullerton, CA, USAAbstract: Age-related macular degeneration (AMD) is a devastating retinal disease that ...
Ingrid Mooney, James LaMotte
doaj
Hyaluronan-CD44 Interaction Regulates Mouse Retinal Progenitor Cells Migration, Proliferation and Neuronal Differentiation. [PDF]
Stem Cell Rev Rep, 2023 Ma J, Fang X, Chen M, Wang Y, Zhang L.
europepmc +1 more source
Biomaterial Physical Cues as Gene Regulators for Cellular Agriculture
Advanced Genetics, Volume 7, Issue 2, June 2026.This review elucidates how biomaterial physical cues—ranging from matrix stiffness to remote electromagnetic fields—serve as extrinsic regulators of gene expression in cellular agriculture. By identifying central mechanotransduction pathways that bridge physical inputs to genetic remodeling, the authors propose the “Material Genome” concept: a ...
Jianuo Liu, Ye Liu
wiley +1 more source
Investigating temporal function of SOX2 transcription factor in retinal neural progenitor cells
, 2010 Generation of the appropriate types and numbers of neurons and glia in the developing central nervous system (CNS) relies on complex networks of cell-intrinsic and cell-extrinsic factors regulating the proliferative and differentiating competence of ...
Surzenko, Natalia
core +1 more source
Wharton's jelly mesenchymal stem cells differentiate into retinal progenitor cells.
Neural regeneration research, 2013 Human Wharton's jelly mesenchymal stem cells were isolated from fetal umbilical cord. Cells were cultured in serum-free neural stem cell-conditioned medium or neural stem cell-conditioned medium supplemented with Dkk-1, a Wnt/β catenin pathway antagonist, and LeftyA, a Nodal signaling pathway antagonist to induce differentiation into retinal progenitor
Hu, Ying +6 more
openaire +2 more sources
Glia, Volume 74, Issue 6, June 2026.Zebrafish pde6c mutants undergo photoreceptor degeneration from 5 dpf, but rods regenerate from 4 wpf. scRNA‐seq of retinal microglia reveals dynamic change of states between 5 dpf and 4 wpf. Two states emerge specifically during regeneration. ABSTRACT Microglia, brain‐resident immune cells, maintain brain homeostasis.
Darshini Ravishankar +2 more
wiley +1 more source
The application of retinal organoids in ophthalmic regenerative medicine: A mini-review
Regenerative TherapyRetinal organoids are three-dimensional (3D) microscopic tissues that are induced and differentiated from stem cells or progenitor cells in vitro and have a highly similar structure to the retina.
Xinmei Lan +4 more
doaj +1 more source
During development of the central nervous system, stem and progenitor cell proliferation and differentiation are controlled by complex inter- and intracellular interactions that orchestrate the precise spatiotemporal production of particular cell types ...
Svendsen, Clive N. +8 more
core +1 more source
Mettl14-mediated m6A modification ensures the cell-cycle progression of late-born retinal progenitor cells. [PDF]
Cell Rep, 2023 Li L +8 more
europepmc +1 more source