Results 121 to 130 of about 23,592 (236)

The application of retinal organoids in ophthalmic regenerative medicine: A mini-review

Regenerative Therapy
Retinal organoids are three-dimensional (3D) microscopic tissues that are induced and differentiated from stem cells or progenitor cells in vitro and have a highly similar structure to the retina.
Xinmei Lan, Huixia Jiang, Qian Wang, Qin Shiqi, Yu Xiong   +4 more
doaj   +1 more source

Novel LAMA1 Mutations in a Pedigree With Poretti‐Boltshauser Syndrome: Implications for Hypomyelination

Molecular Genetics &Genomic Medicine, Volume 14, Issue 5, May 2026.
This study reports novel compound heterozygous LAMA1 variants in two siblings with Poretti‐Boltshauser syndrome presenting with cerebral hypomyelination. It provides the first clinical evidence linking LAMA1 to CNS dysmyelination, expanding the phenotypic spectrum and offering mechanistic insights into this rare association. ABSTRACT Background Poretti‐
Si Huang, Yiyang Li, Jing Xin, Wenhui Mo, Xiuwen Lin, Bingbin Mai, Junbin He, Xiaoli Zhong, Jiaxin Xu   +8 more
wiley   +1 more source

Retinal Progenitor Cells in Regeneration and Repair Highlight New Therapeutic Targets [PDF]

, 2009
E J Mayer, Balini Balasubramaniam, Debra A. Carter, Andrew D. Dick   +3 more
openalex   +1 more source

Electrical Stimulation Induces Retinal Müller Cell Proliferation and Their Progenitor Cell Potential [PDF]

, 2020
Sam Enayati, Karen Chang, Hamida Achour, Kin‐Sang Cho, Fuyi Xu, Shuai Guo, Katarina Zihlavnikova Enayati, Jia Xie, Eric Zhao, Tytteli Turunen, Amer Sehic, Lu Lu, Tor Paaske Utheim, Dong Feng Chen   +13 more
openalex   +1 more source

Human Cytomegalovirus Infection in Haematopoietic Stem Cell Transplant Recipients and CAR T Cell Recipients – PART 1: Risk Factors, Clinical Impact and Immune Response

Reviews in Medical Virology, Volume 36, Issue 3, May 2026.
ABSTRACT Human cytomegalovirus (HCMV) is one of the most important opportunistic pathogens in immunocompromised individuals, including allogeneic haematopoietic stem cell transplant (allo‐HSCT) recipients. In allo‐HSCT, HCMV seropositivity of the recipient and donor is associated with inferior survival outcomes, and post‐transplant HCMV reactivation is
Danya Kaplan, Emily Blyth, Gaurav Sutrave, Michelle K. Yong, David J. Gottlieb, Allison Abendroth, Barry Slobedman, Lauren Stern   +7 more
wiley   +1 more source

From “Passive Supplementation” to “Active Repair”: Melatonin Reshapes the Treatment Paradigm for Late‐Onset Hypogonadism by Targeting Leydig Cell Senescence

Aging Cell, Volume 25, Issue 5, May 2026.
Melatonin restores testosterone production in aging Leydig cells by targeting key pathological drivers, particularly oxidative stress and mitochondrial dysfunction. This approach offers a fundamental strategy to reshape the Late‐onset hypogonadism treatment paradigm.
Hui Wu, Gang Ning, Mintao Jian, Ajian Peng, Haoyu Wang, Bonan Li, Xing Zhou   +6 more
wiley   +1 more source

The Effect of Transient Local Anti-inflammatory Treatment on the Survival of Pig Retinal Progenitor Cell Allotransplants [PDF]

, 2015
Murilo Batista Abud, Petr Baranov, Caroline Hicks, Sara Patel, Burke Lieppman, Caio V. Regatieri, John D. Sinden, David Leonardo Cruvinel Isaac, Marcos Pereira de Ávila, Michael J. Young   +9 more
openalex   +1 more source

Immune Responses to Sequential Binocular Transplantation of Allogeneic Retinal Progenitor Cells to the Vitreous Cavity in Mice. [PDF]

Int J Mol Sci, 2023
Chen L, Yang J, Klassen H.
europepmc   +1 more source

β3‐adrenoceptor agonism exerts lung protection in a rat model of bronchopulmonary dysplasia

British Journal of Pharmacology, Volume 183, Issue 10, Page 2497-2517, May 2026.
The β3‐adrenoceptors agonist BRL37344 promotes lung maturation, preventing the progression of experimental bronchopulmonary dysplasia. Absract Background and Purpose Bronchopulmonary dysplasia (BPD) affects premature newborns, particularly those receiving supplemental oxygen therapy.
Alessandro Pini, Patrizia Nardini, Virginia Zizi, Marta Molino, Maura Calvani, Francesco Carrozzo, Rachele Amato, Daniele Guasti, Denise Biagini, Fabio di Francesco, Ludovico Silvestri, Alessandra Franceschini, Daniele Bani, Elisa Imbimbo, Luca Filippi   +14 more
wiley   +1 more source

Organoid-derived human retinal progenitor cells promote early dedifferentiation of Müller glia in Royal College of Surgeons rats. [PDF]

Int J Ophthalmol, 2023
Guo Q, Zeng YX, Huang SD, Zou T, Yin ZQ.
europepmc   +1 more source