Results 101 to 110 of about 4,562,862 (262)

Expression status transition of NOTCH1 accompanies chromatin remodeling in human early retinal progenitor cells [version 6; peer review: 1 approved, 3 approved with reservations]

F1000Research
Background Notch signaling, especially via the Notch1 receptor, supports normal eye development by maintaining the retinal progenitor cell state before differentiation, although the regulatory mechanism behind fine-tuned Notch1 expression remains unclear.
Masaharu Yoshihara, Satoru Takahashi, Takahiro Nakayama, Sakurako Kobayashi, Yoshitoku Watabe   +4 more
doaj   +1 more source

Comparative Analysis of the Frequency and Distribution of Stem and Progenitor Cells in the Adult Mouse Brain [PDF]

cells (NSCs) and progenitor cells, but it cannot discriminate between these two populations. Given two assays have purported to overcome this shortfall, we performed a comparative analysis of the distribution and frequency of NSCs and progenitor ...
Golmohammadi, Mohammed G., Blackmore, Daniel G, فرانکلین, کیت, اسفندياري, ابراهيم, Rietze, Rodney L., آذری, حسن, لارج, بیترس, Franklin, Keith, B., بلکمور, دانیل, ریتز, رادنی لی, Reynolds, Brent A., Large, Beatrice, Paxinos, Geroge, Azari, Hassan, پاکسینوز, جورج, رینولدز, برنت, Esfandiary, Ebrahim, گل محمدی, محمد قاسم   +17 more
core   +1 more source

Localisation of NG2 immunoreactive neuroglia cells in the rat locus coeruleus and their plasticity in response to stress [PDF]

, 2014
The locus coeruleus (LC) nucleus modulates adaptive behavioural responses to stress and dysregulation of LC neuronal activity is implicated in stress-induced mental illnesses.
Metzger, Friedrich, Friedrich Metzger, Metzger, F, Seifi, Mohsen, Mohsen eSeifi, Johannes J. van der Want, Corteen, Nicole L, Jerome D Swinny, van der Want, Johannes J, Corteen, Nicole L., Seifi, M, Swinny, Jerome D, Corteen, NL, Johannes Jacobus Van Der Want, Nicole L. Corteen, Swinny, Jerome D., Swinny, JD, van der Want, Johannes J., van der Want, Johannes, Nicole Louise Corteen, Mohsen Seifi, Jerome D. Swinny, Friedrich eMetzger   +22 more
core   +2 more sources

Untethered Electrical Stimulation Using Optoelectricity and Piezoelectricity for Tissue Regeneration

FlexTech, EarlyView.
Untethered electrical stimulation from optoelectronic and piezoelectric materials can aid regeneration of damaged tissue. ABSTRACT Electrical signals are increasingly recognized as important regulators of tissue development and regeneration, with outcomes linked to behaviors including proliferation, differentiation, cell migration, and more.
Ryan Yao, Baochun Xu, Cunjiang Yu
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Computer identification of Notch3 in the neurogenic progenitor cells of mammalian early optic vesicles

BMC Research Notes
Objective The developing mammalian retina initially contains undifferentiated cells, providing a model for investigating the mechanisms of differentiation.
Yoshitoku Watabe, Sakurako Kobayashi, Satoru Takahashi, Masaharu Yoshihara   +3 more
doaj   +1 more source

Expression status transition of NOTCH1 accompanies chromatin remodeling in human early retinal progenitor cells [version 5; peer review: 1 approved, 3 approved with reservations]

F1000Research
Background Notch signaling, especially via the Notch1 receptor, is involved in normal eye development by maintaining retinal progenitor cell state before their differentiation, although the regulatory mechanism of fine-tuned Notch1 expression is unclear.
Masaharu Yoshihara, Satoru Takahashi, Takahiro Nakayama, Sakurako Kobayashi, Yoshitoku Watabe   +4 more
doaj   +1 more source

Organoid-derived C-Kit+/SSEA4− human retinal progenitor cells promote a protective retinal microenvironment during transplantation in rodents

Nature Communications, 2019
Stem cell transplantation to treat retinal degeneration could be limited by the degenerative microenvironment. Here, the authors show that C-Kit+/SSEA4– progenitor cells enriched from human embryonic stem cell derived retinal organoids protect retinal ...
Ting Zou, Lixiong Gao, Yuxiao Zeng, Qiyou Li, Yijian Li, Siyu Chen, Xisu Hu, Xi Chen, Caiyun Fu, Haiwei Xu, Zheng Qin Yin   +10 more
doaj   +1 more source

Pilot trial on determinants of progenitor cell recruitment to the infarcted human myocardium [PDF]

, 2008
Background— Clinical trials indicate a beneficial effect of intracoronary infusion of progenitor cells on myocardial function in patients with ischemic heart disease.
Dimmeler, S, Aicher, A, Röver, R, Brenner, W, Schächinger, V, Döbert, N, Fichtlscherer, S, Seeger, FH, Diener, J, Assmus, B, Menzel, C, Zeiher, AM   +11 more
core  

Dissecting the angiogenic mechanism of pachychoroid polypoidal choroidal vasculopathy

iMeta, EarlyView.
A prognosis‐oriented classification system was established to distinguish Pachy PCV from Non‐pachy PCV using a large multicenter dataset. Comparative plasma multi‐omics profiling of Pachy PCV, Non‐pachy PCV, and normal controls revealed unique upregulation of the fluid shear stress and atherosclerosis (FSS‐AS) and HIF‐1 signaling pathways in Pachy PCV.
Xinyu Zhao, Tiantian Cheng, Wenfei Zhang, Xingwang Gu, Qing Zhao, Yaning Chen, Lihui Meng, Jiaqi Zhang, Bintao Qiu, Lili Li, Shiyu Cheng, Zicheng Wang, Chuting Wang, Yuelin Wang, Zuyi Yang, Zhengming Shi, Ye Guo, Shengzhi Liu, Youxin Chen   +18 more
wiley   +1 more source