Results 91 to 100 of about 4,562,862 (262)

A progressive and cell non-autonomous increase in striatal neural stem cells in the Huntington's disease R6/2 mouse

open access: yes, 2006
Neural stem and progenitor cells are located in the subependyma of the adult forebrain. An increase in adult subependymal cell proliferation is reported after various kinds of brain injury.
Batista, C.M.C.   +5 more
core   +1 more source

Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane   +4 more
wiley   +1 more source

A two-step strategy for neuronal differentiation in vitro of human dental follicle cells [PDF]

open access: yes, 2012
Human dental follicle cells (DFCs) derived from wisdom teeth are precursor cells for cementoblasts. In this study, we recognized that naive DFCs express constitutively the early neural cell marker b-IIItubulin.
Völlner, Florian
core   +1 more source

Zebrafish ventral gastrula fate map reveals neural crest progenitor domain

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Fate maps relate progenitor cell positions to later fates and locations of their progeny, revealing early embryonic organization. Previous zebrafish fate maps identified the origin of germ layers and derivative cell fates, but ventral gastrula progenitor domains were not fully resolved. In particular, the neural crest, a multipotent
Elaine E. Kushkowski, Victoria E. Prince
wiley   +1 more source

MIT/TFE family transcription factors, Mitf and Tfec, redundantly promote pigment cell differentiation and retinal epithelium pigmentation in teleosts

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Transcription factors of the MIT/TFE family—mitfa, mitfb, and tfec—play essential roles in specifying pigment cells derived from neural crest cells in vertebrates. In teleosts, which possess multiple pigment cell types, these factors exhibit partially redundant but largely distinct functions across different pigment lineages.
James Lister   +13 more
wiley   +1 more source

Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling [PDF]

open access: yes, 2003
Background— Transplantation of endothelial progenitor cells (EPCs) improves vascularization and left ventricular function after experimental myocardial ischemia.
Dimmeler, S   +9 more
core  

Novel role of Ras-GTPase Activating Protein SH3 Domain-Binding Protein G3BP in adhesion and migration of 32D myeloid progenitor cells [PDF]

open access: yes, 2012
Rho GTPases are involved in homing and mobilization of hematopoietic stem and progenitor cells due to their impact on cytoskeleton remodeling. We have previously shown that inhibition of Rho, Rac and Cdc42 clearly impairs adhesion of normal and leukemic ...
Schwarz, Kerstin   +8 more
core   +1 more source

Evidence for functional convergence between LZTS2 and DYRK1A during craniofacial development

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Precise control of DYRK1A dosage is essential for embryonic development, including craniofacial morphogenesis. While LZTS2 is among the most consistently identified DYRK1A‐interacting proteins, its roles in embryonic development remain incompletely understood, and its potential contribution to craniofacial development has not been ...
Nicole Cheng   +3 more
wiley   +1 more source

Co-ordinating retinal histogenesis: early cell cycle exit enhances early cell fate determination in the Xenopus retina [PDF]

open access: yes, 2002
The laminar arrays of distinct cell types in the vertebrate retina are built by a histogenic process in which cell fate is correlated with birth order.
Philpott, A.   +4 more
core  

Endogenous Trigeminal Neurons Induce Schwann Differentiation of Donor Stem Cells in Dental Pulp Regeneration via Reciprocal Extracellular Vesicles Interplay

open access: yesExploration, EarlyView.
Our study demonstrates that the host TG coordinates with heterologously implanted SHED to regenerate functional dental pulp through reciprocal EVs’ interplay. EVs derived from implanted stem cells migrate to the host TG to activate axonal regeneration.
Wanmin Zhao   +12 more
wiley   +1 more source

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