Results 151 to 160 of about 24,696 (239)

Hyperglycemia-independent neonatal streptozotocin-induced retinopathy (NSIR) in rats

Frontiers in Pharmacology
Introduction: Chemicals, such as MNU (N-methyl-N-nitrosourea) and NaIO3 (sodium iodate), are widely used to induce retinal degeneration in rodents. Streptozotocin (STZ) is an analog of N-acetyl glucosamine in which an MNU moiety is linked to a hexose and
Yu Lin, Yu Lin, Wenyu Du, Wenyu Du, Xiangyu Fu, Xiangyu Fu, Ling Huang, Ling Huang, Yiwen Hong, Yiwen Hong, Haishan Tan, Haishan Tan, Lirong Xiao, Xiang Ren, Xiang Ren, Yujiao Wang, Yujiao Wang, Danian Chen, Danian Chen   +18 more
doaj   +1 more source

Mechano-Chemical Effect of Gelatin- and HA-Based Hydrogels on Human Retinal Progenitor Cells. [PDF]

Gels, 2023
Dromel PC, Singh D, Alexander-Katz A, Kurisawa M, Spector M, Young M.   +5 more
europepmc   +1 more source

Identification of new markers for the characterization and isolation of breast cancer stem cells

, 2013
Breast cancer is the first human carcinoma for which a putative cancer stem cell subpopulation (BCSC) has been isolated with the CD44+/CD24-/low phenotype.
Leccia, Felicia
core  

Plagl1 regulates the retinal progenitor cell to Müller glial cell transition

PLOS Genetics
Müller glia arise from late-stage retinal progenitor cells (RPCs) as a distinct lineage that diverges from neurogenic trajectories. Here, we identify the maternally imprinted gene Plagl1 as a key transcriptional regulator of gliogenesis in the murine retina. Plagl1
Yacine Touahri, Alissa Pak, Luke Ajay David, Joseph Hanna, Hedy Liu, Yucheng Xiao, Lauren Belfiore, Yaroslav Ilnytskyy, Edwin van Oosten, Nobuhiko Tachibana, Lata Adnani, Jiayi Zhao, Mary Hoffman, Rajiv Dixit, Dawn Zinyk, Cynthia J. Guidos, Volker Enzmann, Pengpeng Bi, Isabelle Aubert, Laurent Journot, Igor Kovalchuk, Yves Sauvé, Jeff Biernaskie, Chao Wang, Satoshi Okawa, Antonio del Sol, Carol Schuurmans   +26 more
openaire   +2 more sources

Cilia in Nervous System Development, Function, and Disease

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley   +1 more source

Pitfalls and missing links in current understanding of 4D genomes

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The spatial and temporal organization of the genome—collectively termed the 4D genome—is pivotal for regulating gene expression, maintaining genome stability, and guiding development. The convergence of chromosome conformation capture technologies, super‐resolution microscopy, and single‐cell epigenomics has transformed our understanding of ...
Michael Q. Zhang
wiley   +1 more source

Characterization of The Retinal Progenitor Cells Generated Using Co-Culture Systems. [PDF]

Cell J, 2022
Momenzadeh S, Karamali F, Atefi A, Nasr-Esfahani MH.   +3 more
europepmc   +1 more source

P2X7 Receptor Modulation of Visual Responses in the Retina

, 2015
Adenosine 5’ triphosphate (ATP)-gated P2X7 receptors (P2X7Rs) are known to act as conduits for photoreceptor and retinal ganglion cell (RGC) damage, consequences of various neurodegenerative conditions within the visual pathway. Growing evidence supports
Chavda, S
core  

T Cell Dysfunction in the Acidic Tumor Microenvironment

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Solid tumors are characterized by profound metabolic and vascular abnormalities that generate a hostile tumor microenvironment (TME) marked by extracellular acidosis, hypoxia, and nutrient deprivation. While the consequences of these conditions for cancer cell behavior have been extensively studied, their impact on anti‐tumor immune responses ...
F. B. Christiansen, E. S. Novella, A. V. Lindemann, J. F. H. Cordes, S. F. Pedersen   +4 more
wiley   +1 more source

Advancing Brain and Body Vascular Imaging in Bipolar Disorder: A Report From the International Society for Bipolar Disorders Vascular Task Force

Bipolar Disorders, Volume 28, Issue 4, June 2026.
ABSTRACT Objectives The heart–brain nexus is increasingly recognized as important for human health. Nonetheless, integration of this perspective in research and treatment remains limited in psychiatry, particularly in bipolar disorder (BD). Multisystem vascular imaging may help elucidate mechanisms linking heart and brain health in BD.
Megan Mio, Pao‐Huan Chen, Kody G. Kennedy, Hilary P. Blumberg, David J. Bond, Eric L. Goldwaser, Fabiano A. Gomes, Jody L. Greaney, Tomas Hajek, Susan L. McElroy, Roger S. McIntyre, Abigail Ortiz, Miguel L. Prieto, Elysha Ringin, Louisa G. Sylvia, Shang‐Ying Tsai, Jess G. Fiedorowicz, Benjamin I. Goldstein   +17 more
wiley   +1 more source