Early RPCs divide predominantly symmetrically and exhibit a high proliferation rate, resulting in rapid retinal growth. Late RPCs divide predominantly asymmetrically and exhibit a low proliferation rate. Our results suggest that TET‐deficient RPCs divide predominantly asymmetrically but exhibit a high proliferation rate.
Galina Dvoriantchikova +3 more
wiley +1 more source
Characterization of The Retinal Progenitor Cells Generated Using Co-Culture Systems. [PDF]
Momenzadeh S +3 more
europepmc +1 more source
Identification of new markers for the characterization and isolation of breast cancer stem cells [PDF]
Breast cancer is the first human carcinoma for which a putative cancer stem cell subpopulation (BCSC) has been isolated with the CD44+/CD24-/low phenotype.
Leccia, Felicia
core
This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh +2 more
wiley +1 more source
Reproducible generation of human retinal ganglion cells from banked retinal progenitor cells: analysis of target recognition and IGF-1-mediated axon regeneration. [PDF]
Subramani M, Van Hook MJ, Ahmad I.
europepmc +1 more source
This review summarizes the pathogenic role of mitochondria in diseases and highlights mitochondrial transfer and transplantation as emerging therapeutic strategies. It systematically discusses how nanomaterials are engineered to facilitate these processes, and critically examines the current challenges and future perspectives for their clinical ...
Yuanyuan Su +9 more
wiley +1 more source
miR-381-3p Cooperated With Hes1 to Regulate the Proliferation and Differentiation of Retinal Progenitor Cells. [PDF]
Wang J +10 more
europepmc +1 more source
The hagfish, a jawless early‐branching vertebrate, has very rudimentary eyes that are diminutive and oddly devoid of melanin pigment. Yet, the degenerate hagfish eye grows throughout life and expresses canonical genes of vertebrate retinal development. ABSTRACT Comparative morphology has revealed fascinating structural and organizational differences in
Sarah N. Bradshaw, William T. Allison
wiley +1 more source
Exosome-mediated inhibition of microRNA-449a promotes the amplification of mouse retinal progenitor cells and enhances their transplantation in retinal degeneration mouse models. [PDF]
Guo CJ +7 more
europepmc +1 more source
Physiological Postnatal Neurogenesis, Development, and Maturation in the Regenerable Retina
Retinal structural remodeling from hatchlings to preadults in axolotls involves neurogenesis, cell redistribution, increased expression of photopsins and connexins, and enhanced inhibitory regulation. The peripheral retina of young animals possesses more columnar undifferentiated cells, resembling the columnar DCX‐positive progenitor cells in the ...
Vivian Y. Pang +4 more
wiley +1 more source

