Results 131 to 140 of about 151,276 (329)
Influence of a small fraction of individuals with enhanced mutations on a population genetic pool [PDF]
, 2009 Computer simulations of the Penna ageing model suggest that already a small fraction of births with enhanced number of new mutations can negatively influence the whole population.Comment: 10 pages including 6 figures ...
Cebrat S. +5 more
core +2 more sources
International Journal of Cancer, EarlyView.Abstract Viral infections play a significant role in cancer development, making detecting viral signatures a promising approach for early cancer diagnosis. Circulating free DNA (cfDNA), released into the bloodstream by tumors and other cells, has emerged as a powerful biomarker for non‐invasive cancer screening.
Richard Donkor Amponsah +4 more
wiley +1 more source
Large interstitial del(13)(q13q14.3): the importance of detailed clinical information in cytogenetic studies [PDF]
, 2011 Interstitial deletions of chromosome 13 are known to be associated with retinoblastoma. A wider syndrome may accompany the deletion, including mental retardation and craniofacial dysmorphism.
Correia, Hildeberto +6 more
core
International Journal of Cancer, EarlyView.What's New? Childhood cancer ranks among the leading causes of disease‐related deaths in children in high‐income countries. Established risk factors, however, account for only a small proportion of incident childhood cancers. In this report, the authors present the first long‐term assessment of temporal trends in childhood cancer incidence rates in ...
Friederike Erdmann +8 more
wiley +1 more source
Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer
International Journal of Cancer, EarlyView.Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley +1 more source
LncRNA AFAP1-AS1 is a prognostic biomarker and serves as oncogenic role in retinoblastoma
Bioscience Reports, 2018 The actin filament-associated protein 1 antisense RNA 1 (AFAP1-AS1) has been found to serve as an oncogenic long noncoding RNA (lncRNA) in most types of human cancer. The role of AFAP1-AS1 in retinoblastoma remains unknown.
F. Hao +4 more
semanticscholar +1 more source
Diagnosis and classification of uterine fibroids
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Uterine fibroids, or leiomyomas, are benign uterine tumors with a lifetime prevalence of approximately 75%. While only a minority become symptomatic, their impact on quality of life remains profound owing to heavy menstrual bleeding, bulk symptoms, and reproductive dysfunction.
Rosa Lakabi +5 more
wiley +1 more source
Journal of Ophthalmology, 2020 Purpose. To investigate the clinical presentations and outcomes of retinoblastoma in relation to the advent of new multimodal treatments in Thailand. Patients and Methods. Retrospective case series.
Duangnate Rojanaporn +9 more
doaj +1 more source
ACVR1C/SMAD2 signaling promotes invasion and growth in retinoblastoma
Oncogene, 2018 Retinoblastoma is the most common intraocular cancer in children. While the primary tumor can often be treated by local or systemic chemotherapy, metastatic dissemination is generally resistant to therapy and remains a leading cause of pediatric cancer ...
L. Asnaghi +15 more
semanticscholar +1 more source