Results 131 to 140 of about 93,615 (295)
MedComm – Oncology, Volume 4, Issue 3, September 2025.TGF‐β inhibition is emerging as a promising cancer therapy, yet translating laboratory success to bedside implementation has suffered significant setbacks. The associated challenges include adverse drug reactions, inadequate predictive models, and activation of alternative signaling pathways.
Faizah A. Alabi +5 more
wiley +1 more source
Retinoblastoma occurring in four successive generations. [PDF]
, 1976 C. Migdal
openalex +1 more source
Cellular Senescence in Cancer: Mechanisms, Roles in Tumor Progression, and Therapeutic Implications
MedComm – Oncology, Volume 4, Issue 3, September 2025.Senescent tumor cells in TME exhibit dual roles. “Angels” secrete SASPs/DAMPs to boost immunological clearance and antitumor immunity via MHC‐I upregulation; “Demons” produce tumor‐promoting SASPs recruiting MDSCs to drive malignancy. ABSTRACT Cellular senescence, a state of irreversible cell cycle arrest accompanied by a senescence‐associated ...
Jingrui Yan +5 more
wiley +1 more source
The retinoblastoma protein and cell cycle control
Cell, 1995 R. Weinberg
semanticscholar +1 more source
Childhood Cancer Survivors in Latin America: Insights Into Health Outcomes and Information Needs
Pediatric Blood &Cancer, Volume 72, Issue 9, September 2025.ABSTRACT Background Childhood cancer survivors (CCSs) face long‐term health challenges, yet the health and specific needs of Latin American survivors remain underexplored. This study aimed to describe the health‐related, psychosocial late effects, and information needs among CCSs in the region. Methods This mixed‐method study combined quantitative data
Ana Carolina Izurieta‐Pacheco +17 more
wiley +1 more source
Controlling gene expression through five zinc finger domains of ZNF18
Protein Science, Volume 34, Issue 9, September 2025.Abstract Zinc finger (ZF) proteins are the most abundant transcription factors in vertebrates, and they regulate gene expression through interactions with cis‐acting elements. ZF domains selectively recognize specific sequences to accelerate or repress target genes.
Soyeon Park +4 more
wiley +1 more source
Retinoblastoma: a study of natural history and prognosis of 268 cases. [PDF]
, 1975 E L Lennox, G J Draper, B M Sanders
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Inherited Susceptibility to Cancer: Past, Present and Future
Annals of Human Genetics, Volume 89, Issue 5, Page 354-365, September 2025.ABSTRACT Germline pathogenic variants (GPVs, ‘mutations’) causing inherited susceptibility to certain cancers (cancer susceptibility genes, CSGs) broadly belong to one of two main classes—loss of function variants in tumour suppressor genes (TSGs) or gain of function variants in proto‐oncogenes (an over‐simplification).
Shirley V. Hodgson +3 more
wiley +1 more source
Incidence of retinoblastoma in the Bantu of South Africa. [PDF]
, 1976 Jeffrey Freedman, Lior Goldberg
openalex +1 more source