Results 51 to 60 of about 151,276 (329)
Expression of MMP-14 and CD44 associated with proliferation of retinoblastoma cells
Medicine Science, 2019 Retinoblastoma is a the most common primary intraocular malignant tumor in childhood. The eexpressions of CD44 and MMP-14 and Their role in proliferation and migration cells appear crucial for retinoblastoma invasion.
Hendrian D. Soebagjo +4 more
doaj +1 more source
A Review of Literature on Health-Related Quality of Life of Retinoblastoma Survivors. [PDF]
, 2020 Background: Retinoblastoma is a malignant tumor of the eye that typically presents in early childhood and occurs in approximately 1 in 20,000 births. While active treatment of the tumor is typically completed in childhood, survivors often suffer from ...
Belson, Paula J +4 more
core
Retinoblastoma genetics in India: From research to implementation
Indian Journal of Ophthalmology, 2015 Retinoblastoma is the prototypic genetic cancer. India carries the biggest burden of retinoblastoma globally, with an estimated 1500 new cases annually.
Helen Dimaras
doaj +1 more source
Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression. [PDF]
, 2020 Retinoblastoma is an aggressive childhood cancer of the developing retina that initiates by biallelic RB1 gene inactivation. Tumor progression in retinoblastoma is driven by epigenetics, as retinoblastoma genomes are stable, but the mechanism(s) that ...
Benavente, Claudia A +8 more
core
RB loss contributes to aggressive tumor phenotypes in MYC-driven triple negative breast cancer [PDF]
, 2015 Triple negative breast cancer (TNBC) is characterized by multiple genetic events occurring in concert to drive pathogenic features of the disease. Here we interrogated the coordinate impact of p53, RB, and MYC in a genetic model of TNBC, in parallel with
Ertel, Adam +5 more
core +1 more source
A rare case of adult onset retinoblastoma
Oman Journal of Ophthalmology, 2011 Retinoblastoma usually manifests before five years of age. Retinoblastoma in an adult is extremely rare. Twenty-three cases of retinoblastoma in adults 20 years or older have been reported in world literature.
Sunil Kumar Singh +7 more
doaj +1 more source
Retinoblastoma Tumor Suppressor Protein Roles in Epigenetic Regulation
Cancers, 2020 Simple Summary Loss of function of the retinoblastoma gene (RB1) is the rate-limiting step in the initiation of both the hereditary and sporadic forms of retinoblastoma tumor.
Frederick Guzman +5 more
semanticscholar +1 more source
Nigerian Journal of Medicine, 2022 Background: Retinoblastoma, although rare, is the most frequently occurring primary intraocular tumor of childhood. While a cure is often achieved where appropriate treatment is instituted early in the disease, late presentation often leads to ...
Elizabeth Dennis Nkanga +7 more
doaj +1 more source
Intra-arterial chemotherapy in retinoblastoma – A paradigm change
Indian Journal of Ophthalmology, 2019 Intra-arterial chemotherapy (IAC), also known as superselective ophthalmic artery chemotherapy or chemosurgery, is currently widely accepted as one of the primary treatment modalities for intraocular retinoblastoma worldwide.
Fairooz P Manjandavida +4 more
semanticscholar +1 more source
Cancers, 2020 Simple Summary Retinoblastoma is a rare cancer that develops in the retina of children. Accurate differentiation between retinoblastoma and conditions that show similarities with retinoblastoma (pseudoretinoblastoma or retinoblastoma mimickers) is vital ...
Robin W. Jansen +16 more
semanticscholar +1 more source