Results 51 to 60 of about 145,462 (345)
Expression of MMP-14 and CD44 associated with proliferation of retinoblastoma cells
Medicine Science, 2019 Retinoblastoma is a the most common primary intraocular malignant tumor in childhood. The eexpressions of CD44 and MMP-14 and Their role in proliferation and migration cells appear crucial for retinoblastoma invasion.
Hendrian D. Soebagjo +4 more
doaj +1 more source
Testing Monte Carlo absolute dosimetry formalisms for a small field `D'-shaped collimator used in retinoblastoma external beam radiotherapy [PDF]
Biomeical Physics & Engineering Express 2 (2016) 065008, 2018 Purpose: To investigate the validity of two Monte Carlo simulation absolute dosimetry approaches in the case of a small field dedicated `D'-shaped collimator used for the retinoblastoma treatment with external photon beam radiotherapy. Methods: The Monte Carlo code {\sc penelope} is used to simulate the linac, the dedicated collimator and a water ...
arxiv +1 more source
Pharmacokinetics, Safety, and Efficacy of Intravitreal Digoxin in Preclinical Models for Retinoblastoma [PDF]
, 2015 PURPOSE:To assess in vitro cytotoxic activity and antiangiogenic effect, ocular and systemic disposition, and toxicity of digoxin in rabbits after intravitreal injection as a potential candidate for retinoblastoma treatment.METHODS:A panel of two ...
Abramson, David +13 more
core +2 more sources
Retinoblastoma genetics in India: From research to implementation
Indian Journal of Ophthalmology, 2015 Retinoblastoma is the prototypic genetic cancer. India carries the biggest burden of retinoblastoma globally, with an estimated 1500 new cases annually.
Helen Dimaras
doaj +1 more source
Monte Carlo study for designing a dedicated `D'-shaped collimator used in the external beam radiotherapy of retinoblastoma patients [PDF]
Medical Physics 41 (2014) 011714, 2018 Purpose: The purpose of the present article is to propose a modified version of the D-shaped collimator used at the Univ. Hosp. of Essen for retinoblastoma treatment that reduces even further the irradiation field with the scope to reduce the risk of radio-induced secondary malignancies.
arxiv +1 more source
Cancer Medicine, 2020 The enucleation rate for retinoblastoma has dropped from over 95% to under 10% in the past 10 years as a result of improvements in therapy. This reduces access to tumor tissue for molecular profiling, especially in unilateral retinoblastoma, and hinders ...
Prachi Kothari +17 more
semanticscholar +1 more source
A rare case of adult onset retinoblastoma
Oman Journal of Ophthalmology, 2011 Retinoblastoma usually manifests before five years of age. Retinoblastoma in an adult is extremely rare. Twenty-three cases of retinoblastoma in adults 20 years or older have been reported in world literature.
Sunil Kumar Singh +7 more
doaj +1 more source
A study of the irradiation technique used for the external beam radiotherapy of retinoblastoma [PDF]
Physics in Medicine and Biology 57 (2012) 7741-7751, 2018 Purpose: Retinoblastoma (RB) is the most common eye tumor in childhood and can be treated external radiotherapy. The purpose of this work is to evaluate the adequacy of Monte Carlo simulations and the accuracy of a commercial treatment planning system by means of experimental measurements.
arxiv +1 more source
Cancers, 2020 Simple Summary Retinoblastoma is a rare cancer that develops in the retina of children. Accurate differentiation between retinoblastoma and conditions that show similarities with retinoblastoma (pseudoretinoblastoma or retinoblastoma mimickers) is vital ...
Robin W. Jansen +16 more
semanticscholar +1 more source
Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression. [PDF]
, 2020 Retinoblastoma is an aggressive childhood cancer of the developing retina that initiates by biallelic RB1 gene inactivation. Tumor progression in retinoblastoma is driven by epigenetics, as retinoblastoma genomes are stable, but the mechanism(s) that ...
Benavente, Claudia A +8 more
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