The Incidence of Trilateral Retinoblastoma : A Systematic Review and Meta-Analysis [PDF]
PURPOSE: To estimate the incidence of trilateral retinoblastoma in patients with retinoblastoma. " DESIGN: Systematic review and meta-analysis. METHODS: We searched Medline and Embase for scientific literature published between January 1966 and July 2015
Castelijns, Jonas A.+5 more
core +1 more source
Retinoblastoma Tumor Suppressor Protein Roles in Epigenetic Regulation
Simple Summary Loss of function of the retinoblastoma gene (RB1) is the rate-limiting step in the initiation of both the hereditary and sporadic forms of retinoblastoma tumor.
Frederick Guzman+5 more
semanticscholar +1 more source
A Review of Literature on Health-Related Quality of Life of Retinoblastoma Survivors. [PDF]
Background: Retinoblastoma is a malignant tumor of the eye that typically presents in early childhood and occurs in approximately 1 in 20,000 births. While active treatment of the tumor is typically completed in childhood, survivors often suffer from ...
Belson, Paula J+4 more
core
The risk factor of metastatic status of retinoblastoma patient in Yogyakarta Tertiary Hospital [PDF]
The metastases of the tumor become a serious problem malignancy including retinoblastoma. This study aimed to observe the correlation between several risk factors with the metastatic status of retinoblastoma patients in Yogyakarta Tertiary Hospital ...
Dibyasakti, Banu Aji+5 more
core +1 more source
Therapeutic targeting of the RB1 pathway in retinoblastoma with the oncolytic adenovirus VCN-01
An oncolytic adenovirus shows antitumor efficacy in patient-derived models of intraocular retinoblastoma and appears safe for human use. An oncolytic virus to blast retinoblastoma Eyes afflicted by chemoresistant retinoblastoma may need to be surgically ...
Guillem Pascual-Pasto+40 more
semanticscholar +1 more source
Retinoblastoma in an adult [PDF]
Retinoblastoma is the most common pediatric ocular tumour. It may rarely present in adults. The present case adds to the number of 26 cases already published in literature since 1919 till 2013. Our aim is to highlight the rare occurrence of retinoblastoma in adults along with its features which differentiate it from paediatric retinoblastoma.We ...
Nadeem Zafar+2 more
openaire +3 more sources
Characterization of the Portuguese population diagnosed with retinoblastoma
The purpose of this study is to characterize demographically and genetically the Portuguese population with retinoblastoma; to report the clinical stage at presentation and its impact on survival and ocular preservation rate and, finally, to assess the ...
Guilherme Castela+9 more
doaj +1 more source
The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness. [PDF]
PURPOSE: Perturbations in the retinoblastoma pathway are over-represented in advanced prostate cancer; retinoblastoma loss promotes bypass of first-line hormone therapy.
Addya, Sankar+14 more
core +1 more source
Intra-arterial chemotherapy in retinoblastoma – A paradigm change
Intra-arterial chemotherapy (IAC), also known as superselective ophthalmic artery chemotherapy or chemosurgery, is currently widely accepted as one of the primary treatment modalities for intraocular retinoblastoma worldwide.
Fairooz P Manjandavida+4 more
semanticscholar +1 more source
Molecular analysis distinguishes metastatic disease from second cancers in patients with retinoblastoma [PDF]
The pediatric ocular tumor retinoblastoma readily metastasizes, but these lesions can masquerade as histologically similar pediatric small round blue cell tumors.
Argiropoulos, Bob+11 more
core +1 more source