Questionnaire study to gain an insight into the manufacturing and fitting process of artificial eyes in children: an ocularist perspective [PDF]
, 2016 Purpose To gain an insight into the manufacturing and fitting of artificial eyes in children and potential improvements to the process. Method An online qualitative survey was distributed to 39 ocularists/prosthetists in Europe and Canada ...
A Clarke +29 more
core +2 more sources
Retinoblastoma: A spectrum of manifestations in three cases on B-scan
Indian Journal of Radiology and Imaging, 2007 Retinoblastoma is a primary intraocular neoplasm of childhood, presenting with leukocoria.We present a spectrum of three cases. First two cases are of bilateral retinoblastoma and last case is a retinoblastoma of right eye.
V. D. Aironi +3 more
doaj +1 more source
Inhibitory activity of bevacizumab to differentiation of retinoblastoma cells. [PDF]
PLoS ONE, 2012 Vascular endothelial growth factor (VEGF) is a major regulator in retinal and choroidal angiogenesis, which are common causes of blindness in all age groups.
Jang Won Heo +6 more
doaj +1 more source
Therapeutic targeting of the RB1 pathway in retinoblastoma with the oncolytic adenovirus VCN-01
Science Translational Medicine, 2019 An oncolytic adenovirus shows antitumor efficacy in patient-derived models of intraocular retinoblastoma and appears safe for human use. An oncolytic virus to blast retinoblastoma Eyes afflicted by chemoresistant retinoblastoma may need to be surgically ...
Guillem Pascual-Pasto +40 more
semanticscholar +1 more source
Signalling, cell cycle and pluripotency in embryonic stem cells [PDF]
, 2002 International ...
Burdon, Tom +2 more
core +1 more source
Nitric oxide suppression by secreted frizzled-related protein 2 drives retinoblastoma
Cell Reports, 2023 Summary: Retinoblastoma is a cancer of the infant retina primarily driven by loss of the Rb tumor suppressor gene, which is undruggable. Here, we report an autocrine signaling, mediated by secreted frizzled-related protein 2 (SFRP2), which suppresses ...
Panneerselvam Jayabal +10 more
doaj +1 more source
Bioengineered, 2020 Retinoblastoma is the commonest eye cancer occurring in the pediatric population. Circular RNAs (circRNAs) are essential regulators of tumorigenesis and development.
Zhe Sun, Ai Zhang, Mingyu Hou, T. Jiang
semanticscholar +1 more source
Current therapy and recent advances in the management of retinoblastoma
Indian Journal of Medical and Paediatric Oncology, 2012 Retinoblastoma is the most common intraocular malignancy in children. The survival of retinoblastoma patients and visual outcome has improved dramatically in the developed world.
Rachna Meel +2 more
doaj +1 more source
Adjuvant therapy for children treated by enucleation at diagnosis of retinoblastoma
EJC Paediatric Oncology, 2023 Introduction: Advanced localized retinoblastoma can be cured by enucleation, but extraocular spread of retinoblastoma cells is associated with a high mortality.
Yelena Diarra +27 more
doaj +1 more source
The real war on cancer: the evolutionary dynamics of cancer suppression. [PDF]
, 2012 Cancer is a disease of multicellular animals caused by unregulated cell division. The prevailing model of cancer (multistage carcinogenesis) is based on the view that cancer results after a series of (generally somatic) mutations that knock out the ...
Nunney, Leonard
core +1 more source