Results 131 to 140 of about 2,794,061 (304)

Retinoic Acid Generates Regulatory T Cells in Experimental Transplantation [PDF]

, 2020
Regulatory T cells play a key role to inhibit effector lymphocytes, avoid, autoimmunity, and restrain allogeneic immunity. Retinoic acid is an important cofactor that stimulates the generation and expansion of regulatory T cells.
C Fuentes, J A Fierro, M Rosemblatt, J Morales, D Sauma, C Moore, M R Bono   +6 more
core  

Evaluation of Retinoic Acid Ophthalmic Emulsion in Dry Eye

, 2000
Purpose An oil in water emulsion of 0.01% all-trans-retinoic acid (tretinoin) was prepared and clinically evaluated in dry eye patients. Methods The ophthalmic emulsion consisted of 10% of arachis oil and 90% of the hydro-gel of Carbopol 940. To evaluate
M. Orhan, H. Selek, M. Irkeç, N. Ünlü
core   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Histological and Morphometric Study on the Effects of Excess Retinoic Acid on Prenatal Liver Development in Albino Rats and the Potential Protective Role of Folic Acid.

The Egyptian Journal of Histology
Background: With appearance of excess use of vitamins and multivitamin regimens, Retinoic acid (RA) is a metabolite of vitamin A that is fundamental for cell growth and differentiation.Aim of the Work: To examine the impact of excess retinoic acid on the
Ghobrial Mikhaeel, Hala Mohamed, Reffat Mohamed, Amany Zaki   +3 more
doaj   +1 more source

OXCT1‐driven succinylation of PSMG3 stabilizes the proteasome to facilitate picornavirus replication

iMetaOmics, EarlyView.
Upon entering the pig, foot‐and‐mouth disease virus (FMDV) regulates host glycolysis and the citrate cycle by modulating the expression of metabolic enzymes, resulting in changes in post‐translational modifications (PTMs) including succinylation, lactylation, crotonylation, acetylation, and phosphorylation.
Huisheng Liu, Qiao Xue, Pengfei Liu, Zhihua Dong, Weijun Cao, Fan Yang, Yingming Zhu, Lei Deng, Zixiang Zhu, Haixue Zheng   +9 more
wiley   +1 more source

High‐Content Screening Comparison of 1R6F Cigarette Smoke Extract and Selected Heated Tobacco and Electronic Vapour Product Aerosol Extracts in Endothelial and Bronchial Epithelial Cell Models

Journal of Applied Toxicology, EarlyView.
ABSTRACT Cigarettes induce oxidative stress and DNA damage, processes that contribute to cardiovascular and pulmonary disease. High content screening (HCS) is an increasingly valuable tool for comparative toxicology because it enables simultaneous quantification of multiple mechanistic endpoints at single‐cell resolution. In this study, HCS was used to
Edgar Trelles Sticken, Konstantinos Papikinos, Fiona Chapman, Roman Wieczorek, Sarah Jean Pour, Torge Evenburg, Sandra Otte, Tiandan Wu, Liam Simms, Matthew Stevenson   +9 more
wiley   +1 more source

Retinoids in neuroblastoma therapy: Distinct biological properties of 9- cis- and all-trans-retinoic acid

, 1997
We investigated the potential for 9-cis-retinoic acid in the differentiation therapy of neuroblastoma using an N-type neuroblastoma cell line, SH SY 5Y, as an experimental model. In these cells, 9-cis-retinoic acid is more effective than other isomers at
Bernassola F, Annicchiarico-Petruzzelli M, Lovat PE, Pearson ADJ, Melino G, Redfern CPF, Irving H, Malcolm AJ   +7 more
core   +2 more sources

Transparent Surfactant‐Based Isotropic Systems for Topical Co‐Delivery of Hydrophilic and Lipophilic Actives for Striae Distensae

Journal of Surfactants and Detergents, EarlyView.
ABSTRACT Striae distensae are common dermal lesions that negatively affect skin appearance, and topical management remains limited by challenges related to skin deposition and residence time. Here, we developed transparent surfactant‐based isotropic systems for the topical co‐delivery of ascorbic acid (AA), retinoic acid (RA), and lavender essential ...
Claudiane Ayres Prochno, Anna Paula Brusamarello, Anna Cláudia Morais de Oliveira Capote, Thais Leticia Moreira da Silva, Gabriela Ruva Fagundes, Giovani Marino Favero, Marina Tolentino Marinho, Benjamim Melo de Carvalho, Priscileila Colerato Ferrari   +8 more
wiley   +1 more source

Impurity analysis of retinoic acid samples

, 2005
The structure of an impurity contained in samples of all trans-retinoic acid was established by means of NMR and MS spectra, and confirmed by X-ray diffraction analysis.
Fronza G, Fuganti C, Allegrone G, Giovenzana T, Barlocchi E, Pellegatta C, Brenna E, Malpezzi L   +7 more
core  

Macronutrient and micronutrient profiles of meat types: insights into human health and diet

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Despite considerable advances in global health and nutrition, emerging challenges such as population growth, climate change, and limited natural resources continue to threaten food security. Meat remains an essential component of the human diet, supplying high‐quality proteins, essential amino acids, lipids, vitamins, and minerals necessary ...
Özgül Anitaş, Serap Göncü, Fatma Hepsağ, Nazan Koluman, Yesim Ozogul   +4 more
wiley   +1 more source