Results 141 to 150 of about 222,098 (349)
The Role of Retinoic Acid (RA) in Spermatogonial Differentiation1 [PDF]
, 2015 Jonathan T. Busada, Christopher B. Geyer
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Recruitment of Nuclear Receptor Corepressor and Coactivator to the Retinoic Acid Receptor by Retinoid Ligands [PDF]
, 2000 Elliott Klein +4 more
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High Albumin Levels Restrict the Kinetics of 13-cis Retinoic Acid Uptake and Intracellular Isomerization to All-trans Retinoic Acid and Inhibit its Anti-Proliferative Effect on SZ95 Sebocytes [PDF]
, 2002 Miki Tsukada +4 more
openalex +1 more source
Somatic cell reprogramming for Parkinson's disease treatment
Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
All-Trans Retinoic Acid Attenuates Fibrotic Processes by Downregulating TGF-β1/Smad3 in Early Diabetic Nephropathy [PDF]
, 2019 Edith Sierra-Mondragón +6 more
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Interdisciplinary Medicine, EarlyView.SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu +6 more
wiley +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Humans are chronically exposed to mixtures of environmental contaminants. Exposure to endocrine‐disrupting chemicals (EDCs) contributes to increased health impairment observed globally. This study aimed to evaluate the endocrine‐disruptive and oxidative stress potential of a human‐relevant, complex chemical mixture in vitro.
Josefin Engelhardt +5 more
wiley +1 more source
PML–RARα induces all-trans retinoic acid-dependent transcriptional activation through interaction with MED1 [PDF]
, 2019 Tomoya Fukuoka +6 more
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JEADV Clinical Practice, EarlyView.ABSTRACT Differentiation syndrome (DS) and Sweet syndrome (SS) are inflammatory complications mediated by cytokine dysregulation, classically associated with therapies that promote myeloid differentiation or cytokine release. While DS has been primarily linked to all‐trans retinoic acid (ATRA) and IDH inhibitors, recent evidence suggests that ...
Katerina Grafanaki +6 more
wiley +1 more source