Results 121 to 130 of about 6,065,806 (347)

Retinoic acid syndrome in a elderly male with psoriasis- A case report

Respiratory Medicine Case Reports, 2018
The retinoic acid derivatives are used for disorders of keratinization such as psoriasis. Retinoic acid syndrome is a cytokine release syndrome, commonly encountered in patients with acute promyelocytic leukaemia (APL).
Chandan Metage, Basanta Hazarika, Jogesh Sarma, Rahul Karwa   +3 more
doaj   +1 more source

Retinoic acid's reproducible future [PDF]

Science, 2017
Science is facing a reproducibility crisis. In the biomedical sciences, the inability to validate and reproduce findings is slowing progress in understanding basic biological principles. Among the fields hindered by irreproducibility is retinoic acid (RA) research.
openaire   +2 more sources

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

Advanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu, Zhihao Zhan, Xiaoxiang Pan, Xinyue Zhang, Penggang Liu, Jing Sun, Xiulong Xu   +6 more
wiley   +1 more source

Effects of retinoic acid on the incidence of neural tube defects and other malformations in mice with the quinky gene

, 1992
Matings between normal young adult ac/ae female mice and heterozygous Quinky BALB/c males were used to study reported teratogenic and/or preventive effects of retinoic acid (RA) utilizing a mutation that produces neural tube defects (NTDs).
Abou-Tarboush, F.M.
core  

Enzymology of retinoic acid biosynthesis and degradation

Journal of Lipid Research, 2013
All-trans-retinoic acid is a biologically active derivative of vitamin A that regulates numerous physiological processes. The concentration of retinoic acid in the cells is tightly regulated, but the exact mechanisms responsible for this regulation are ...
Natalia Y. Kedishvili
doaj   +1 more source

In vitro epigenetic reprogramming of human cardiac mesenchymal stromal cells into functionally competent cardiovascular precursors [PDF]

, 2012
Adult human cardiac mesenchymal-like stromal cells (CStC) represent a relatively accessible cell type useful for therapy. In this light, their conversion into cardiovascular precursors represents a potential successful strategy for cardiac repair.
Andrea Barbuti (106295), A. Barbuti, Rossini, Alessandra, Simona Nanni, Nanni, Simona, Barbuti, Andrea, C. Gaetano, Meraviglia Viviana, Carlo Gaetano (110837), Meraviglia, Viviana, Capogrossi, Maurizio C., Pompilio Giulio, Gualtiero I Colombo, Angela Scavone, Simona Nanni (110816), Maurizio C Capogrossi, S. Nanni, Scavone Angela, Matteo Vecellio, Viviana Meraviglia (110811), DiFrancesco Dario, A. Scavone, Antonella Farsetti, Alessandra Rossini (110841), Viviana Meraviglia, Colombo Gualtiero I., Dario DiFrancesco, Pompilio, Giulio, Gaetano, Carlo, Vecellio, Matteo, Nanni Simona, Maurizio C. Capogrossi (103525), D. DiFrancesco, Giulio Pompilio (103510), Gaetano Carlo, Carlo Gaetano, Colombo, Gualtiero I., Vecellio Matteo, Farsetti Antonella, A. Farsetti, Angela Scavone (110822), M. Vecellio, Farsetti, Antonella, Barbuti Andrea, Capogrossi Maurizio C., Rossini Alessandra, G.I. Colombo, Giulio Pompilio, Antonella Farsetti (110827), V. Meraviglia, Alessandra Rossini, Andrea Barbuti, DiFrancesco, Dario, Dario DiFrancesco (106304), M. C. Capogrossi, Gualtiero I. Colombo (103516), Scavone, Angela, Matteo Vecellio (110807), A. Rossini, G. Pompilio   +59 more
core   +1 more source

Distinct Neuropsychiatric Profiles Associated With 17p11.2 Deletions and RAI1 Variants in Smith–Magenis Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Smith–Magenis syndrome (SMS) results from either a recurrent 17p11.2 deletion or pathogenic variants in the retinoic acid induced 1 gene (RAI1). While neurodevelopmental impairment and behavioral dysregulation are well recognized, systematic genotype‐stratified analyses across psychiatric domains remain limited.
Albin Blanc, Christophe Nemos, Céline Bonnet, Mathilde Renaud, Sandra Chapuis, Pauline Boiroux, Marie‐Noëlle Babinet, Caroline Demily   +7 more
wiley   +1 more source

Sweet's syndrome involoving the musculoskeletal system during treatment of promyelocytic leukemia with all-trans retinoic acid

, 1996
Induction therapy of promyelocytic leukemia with all-trans retinoic acid is a standard therapy despite significant side-effects. The most important, the "retinoic acid syndrome", consists of a hyperinflammatory reaction with capillary leakage (edema ...
Speich, R, Schaffner, A, Christ, E, Marincek, B, Jacky, E, Linka, A   +5 more
core  

The cellular retinoic acid binding proteins

, 1995
The two cellular retinoic acid binding proteins, CRABP I and CRABP II, belong to a family of small cytosolic lipid binding proteins and are highly conserved during evolution.
Olofsson, B, Dencker, L, Gustafson, AL, Donovan, M, Eriksson, U,   +4 more
core   +1 more source

Retinoic acid triazole promotes neurotrophin-mediated cell growth and proliferation in nerve cells

Bangladesh Journal of Pharmacology, 2014
In the present study, fluorophenyl retinoic acid triazole, a retinoic acid derivative having more bioavailability compared to the parent retinoic acid was investigated against cell growth and proliferation.
Hui Shi, Yan Xiao Long, Yi Zhang, Ming Zhong, Kuang Zheng   +4 more
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