Results 121 to 130 of about 222,098 (349)

Inhibition of thrombin, an unexplored function of retinoic acid

Biochemistry and Biophysics Reports, 2019
Retinoic acid, a derivative of vitamin A, is known to possess in vivo anti-inflammatory, anti-platelet and fibrinolytic activities. We have investigated the in vitro thrombin and platelet aggregation inhibitory activities of vitamin A (retinol) and its ...
Tirumala Harikrishna Anantha Krishna, Subban Kamalraj, Maheswaraiah Anikisetty, K. Akhilender Naidu, William R. Surin, Chelliah Jayabaskaran   +5 more
doaj   +1 more source

Supplementary Figure Legends 1-2 from A Retinoic Acid—Rich Tumor Microenvironment Provides Clonal Survival Cues for Tumor-Specific CD8⁺ T Cells [PDF]

, 2023
Yanxia Guo, Karina Pino‐Lagos, Cory A. Ahonen, Kathy A. Bennett, Jinshan Wang, Joseph L. Napoli, Rune Blomhoff, Shanthini Sockanathan, Roshantha A.S. Chandraratna, Ethan Dmitrovsky, Mary Jo Turk, Randolph J. Noelle   +11 more
openalex   +1 more source

Neuronal differentiation and tissue engineering strategies for central neurous system injury repair

BMEMat, EarlyView.
This review outlines tissue engineering advances for central nervous system (CNS) injury treatment, focusing on three core components: seed cells, inductive factors, and scaffold materials, with evaluation of their respective strengths and limitations. Tissue engineering for CNS injury repair.
Zhuqing Xia, Jinghui Zhang, Na Ren, Shuping Wang, Congcong Zhang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Chao Liu, Chunhui Sun, Jingang Wang   +9 more
wiley   +1 more source

Regulation of adipocyte gene expression by retinoic acid and hormones: effects on the gene encoding cellular retinol-binding protein

Journal of Lipid Research, 1995
Our laboratory has reported that adipose tissue and adipocytes are importantly involved in retinoid storage and metabolism. To gain further insight, we examined factors that may regulate CRBP mRNA levels in primary cultures of rat epididymal and murine ...
M Okuno, V E Caraveo, D S Goodman, W S Blaner   +3 more
doaj   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Bibliometric analysis of research on retinoic acid in the field of kidney disorders

Frontiers in Pharmacology
Retinoic acid is an active metabolite with significant physiological functions in human development, immunity, vision, and skin health. In recent years, research on retinoic acid in the field of kidney disorders has been increasing gradually.
Yu Liu, Yu Liu, Dongxuan Sun, Youqun Huang, Yuli Shen, Tong Chen, Wenya Chen, Liangjun Zhu, Fang Wang, Guoai Hong, Yuechan Luo, Siyu Long, Hequn Zou   +12 more
doaj   +1 more source

Loss, persistence and reversal of phenotypic traits

Biological Reviews, EarlyView.
ABSTRACT The irreversibility of complex trait loss has long been a tenet of evolutionary biology. However, this idea is increasingly at odds with the numerous documented exceptions across the Tree of Life. We synthesise this growing body of evidence across a diverse array of taxa and traits, exploring the evolutionary conditions that enable ...
Giobbe Forni, Giuseppe Fusco, Filippo Nicolini, Heather Bruce, Andrea Luchetti   +4 more
wiley   +1 more source

Examination of Fluconazole-Induced Alopecia in an Animal Model and Human Cohort. [PDF]

, 2019
Fluconazole-induced alopecia is a significant problem for patients receiving long-term therapy. We evaluated the hair cycle changes of fluconazole in a rat model and investigated potential molecular mechanisms.
Aaron, Phylicia A, Affolter, Verena K, Dennis, Michael, Everett, Angela D, Fedor, Dawn M, Gelli, Angie, Krois, Charles R, McHardy, Ian, Napoli, Joseph L, Sharon, Victoria R, Singapuri, Anil, Thompson, George R, Varjonen, E Katarina, White, Stephen D, Wiederhold, Nathan P, Yoo, Hong Sik   +15 more
core  

RORγt‐APCs: The New Masters of Oral Tolerance

Barrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

TULP4, a novel E3 ligase gene, participates in neuronal migration as a candidate in schizophrenia

CNS Neuroscience &Therapeutics, EarlyView., 2023
Mutations identified from four SCZ pedigrees resulted in decreased TULP4 expression. Tulp4 knockdown caused delayed neuron migration in embryonic mice, and impaired cognition and prepulse inhibition in adult mice. These phenotypes may be related to TULP4 through its involvement in the formation of a novel E3 ubiquitin ligases.
Yan Bi, Decheng Ren, Fan Yuan, Zhou Zhang, Daizhan Zhou, Xin Yi, Lei Ji, Keyi Li, Fengping Yang, Xi Wu, Xingwang Li, Yifeng Xu, Yun Liu, Peng Wang, Changqun Cai, Chuanxin Liu, Qian Ma, Lin He, Yi Shi, Guang He   +19 more
wiley   +1 more source