Results 181 to 190 of about 223,790 (352)

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

Combination of cellular retinoic acid-binding protein 2 overexpression and all-trans retinoic acid synergistically inhibits oesophageal squamous cell carcinoma progression. [PDF]

Discov Oncol
Li M, Dai L, Jiang M, Lv Y, Zhang Y, Wang Y, Ma Y.   +6 more
europepmc   +1 more source

Disassociation of MAPK Activation and c-Fos Expression in F9 Embryonic Carcinoma Cells following Retinoic Acid-induced Endoderm Differentiation [PDF]

, 2001
Elizabeth R. Smith, Jennifer L. Smedberg, Malgorzata E. Rula, Thomas C. Hamilton, Xiang-Xi Xu   +4 more
openalex   +1 more source

Cellular Mechanism and Key Insights in Allergen Immunotherapy for Allergic Rhinitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Allergic rhinitis (AR) arises from immune responses mediated by immunoglobulin E (IgE) to inhaled allergens, representing one of the most prevalent chronic conditions worldwide. Although AR may not be a serious ailment, it holds clinical relevance as it underpins numerous complications, serves as a major risk factor for suboptimal asthma ...
Zhe Wang, Teng‐Fei Li, Tian‐Yu Wang, Huan‐Hai Liu   +3 more
wiley   +1 more source

Significance of ETV6 rearrangement in acute promyelocytic leukemia with t(15;17)/promyelocytic leukemia/retinoic acid receptor alpha

, 2016
Na Gao, WEN-ZHENG YU, XUE-XIA WANG, JIAN-RONG SUN, Ning Yu, Zengyan Liu, XIAO-DAN LIU, R Liu, Rui Feng, Butong Ding, Tan Sang, Guo Nong-jian   +11 more
openalex   +2 more sources

Effect of Retinoic Acid on HaCaT and NIH-3T3 cells in an in vitro 3D Collagen Cell Culture Skin Model

, 2023
Olivia Atkins, Samantha Lopez, Yizhe Ma, Louis A. Roberts   +3 more
openalex   +1 more source

Decreased Production of Tissue Plasminogen Activator in Endothelial Cells From Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Previous studies have demonstrated that chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by excessive fibrin deposition which is related to impaired production of tissue plasminogen activator(t‐PA) by epithelial cells.
Qian‐Qian Zhang, Chen Zhang, Jia‐Ni Chen, Fu‐Ying Cheng, Yi‐Zhang Wang, Shi‐Rui Xue, Huan Wang, De‐Hui Wang, Xi‐Cai Sun, Li Hu   +9 more
wiley   +1 more source

All-Trans Retinoic Acid Suppresses Hepatocellular Carcinoma Progression via the CSTB/CYTB Axis. [PDF]

J Cell Mol Med
Sun J, Zheng J, Zhu W, Bi Y, He Y.
europepmc   +1 more source

Postbiotics and Nicotinamide Utilize Distinct Mechanisms to Improve Skin Barrier Integrity, Inflammation, and Keratinocyte Differentiation

Allergy, EarlyView.
Integrating skin barrier measurements with omics and machine learning, we found that postbiotics and NAM regulate skin homeostasis through distinct, strain‐ and dose‐dependent mechanisms. Postbiotics primarily modulate skin barrier function by promoting keratinocyte differentiation and suppressing inflammation.
Yagiz Pat, Duygu Yazici, Huseyn Babayev, Sena Ardicli, Xiangting Bu, Sheri Simmons, Anthony Almada, Christine Avena, Tye Jensen, Raja Dhir, Patrick Westermann, Asuncion Garcia‐Sanchez, Manru Li, Ozge Ardicli, Can Zeyneloglu, Marco Pane, Angela Amoruso, Christoph Messner, Ismail Ogulur, Yasutaka Mitamura, Mubeccel Akdis, Cezmi A. Akdis   +21 more
wiley   +1 more source

Retinoic acid receptor β deletion in podocytes causes kidney and liver dysfunction, modeling nephrotic syndrome. [PDF]

J Mol Endocrinol
Chi Y, DiKun KM, Tang XH, Warren CD, Chikara S, Mere Del Aguila E, Wagner JA, Geri JB, Gudas LJ.   +8 more
europepmc   +1 more source