Results 191 to 200 of about 6,065,806 (347)

Retinoic acid production via the ray-finned fish gene bco1l is essential for juvenile development. [PDF]

open access: yesGenetics
Krupa LS   +6 more
europepmc   +1 more source

A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skin

open access: yesJournal of Cosmetic Dermatology, 2016
R. Kong   +6 more
semanticscholar   +1 more source

Evaluating Thiram‐Induced Embryotoxicity Using Integrated In Silico, In Vitro, and Transcriptomic Approaches

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho   +7 more
wiley   +1 more source

Integrative Bioinformatics, Experimental Validation, and Interpretable Machine Learning Reveal Oxyresveratrol‐Mediated Protection Against Cadmium‐Induced Lung Adenocarcinoma‐Related Transcriptional Dysregulation

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Cadmium (Cd) is a toxic heavy metal strongly implicated in lung adenocarcinoma (LUAD) through mechanisms involving oxidative stress, epigenetic dysregulation, and chronic inflammation. This study aimed to identify Cd‐responsive genes associated with LUAD and to evaluate the protective effects of oxyresveratrol (O‐RES) against Cd‐induced ...
Murat Isıyel, Hamid Ceylan, Yeliz Demir
wiley   +1 more source

Anti-asthma drug montelukast induces autistic behaviors via disrupting neuronal retinoic acid signaling. [PDF]

open access: yesSignal Transduct Target Ther
Hao ZJ   +32 more
europepmc   +1 more source

Cellular Mechanism and Key Insights in Allergen Immunotherapy for Allergic Rhinitis

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Allergic rhinitis (AR) arises from immune responses mediated by immunoglobulin E (IgE) to inhaled allergens, representing one of the most prevalent chronic conditions worldwide. Although AR may not be a serious ailment, it holds clinical relevance as it underpins numerous complications, serves as a major risk factor for suboptimal asthma ...
Zhe Wang   +3 more
wiley   +1 more source

PhD

open access: yes, 2007
dissertationNeuroblastoma is the most common extracranial solid tumor in children. Despite increases in the intensity of treatment of this tumor over the past several decades, the long-term survival of patients with advanced neuroblastoma remains dismal.
Dufner, Jodi Lynn
core  

Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1980
T. Breitman   +3 more
semanticscholar   +1 more source

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