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Retinoic acid and its receptors
The American Journal of Surgery, 1993Retinoic acid (RA)--the active metabolite of vitamin A--and its analogues have pleiotropic effects on growth, differentiation, proliferation, and development. RA, and its analogues, determine embryonic pattern formation and inhibit tumor growth; however, they are also teratogens.
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Immunostimulation by retinoic acid.
Ciba Foundation symposium, 1985Retinoids have been shown to inhibit tumour growth in several model systems. In this paper evidence that immune effectors are important for this effect is discussed. Injection of retinoic acid (RA) into mice before challenge with allogeneic or syngeneic tumour cells results in a strong increase in cell-mediated cytotoxicity specific for the respective ...
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Retinoic Acid, Immunity, and Inflammation
2011Vitamin A (also called retinol), absorbed in the intestine and stored mainly in the liver and fat, is normally maintained at significant concentrations in the human blood plasma. Vitamin A is constitutively metabolized at high levels in certain tissues such as the small intestine and eyes.
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A decade of molecular biology of retinoic acid receptors
The FASEB Journal, 1996P. Chambon
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2010
Retinoids, a group of structural and functional derivatives of vitamin A are known to regulate a large number of essential biological processes such as cell growth, differentiation and death. The retinoic acid (RA) signalling pathway involves the precise regulation of retinoid levels and the control of RA-dependent gene expression in target cells.
Fabien Guidez +4 more
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Retinoids, a group of structural and functional derivatives of vitamin A are known to regulate a large number of essential biological processes such as cell growth, differentiation and death. The retinoic acid (RA) signalling pathway involves the precise regulation of retinoid levels and the control of RA-dependent gene expression in target cells.
Fabien Guidez +4 more
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RETINOIC ACID AND HYPERTRIGLYCERIDEMIA
Annals of the New York Academy of Sciences, 1981Leonard E. Gerber, John W. Erdman
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Retinoic Acid and Immune Homeostasis: A Balancing Act.
Trends in immunology, 2017Martje N Erkelens, R. Mebius
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A human retinoic acid receptor which belongs to the family of nuclear receptors
Nature, 1987M. Petkovich +3 more
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