Results 101 to 110 of about 349,317 (300)

The role of Rho GTPases in facial morphogenesis

open access: yesDevelopmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

All-Trans Retinoic Acid and Sodium Butyrate Enhance Natriuretic Peptide Receptor A Gene Transcription: Role of Histone Modification [PDF]

open access: bronze, 2014
Prerna Kumar   +5 more
openalex   +1 more source

Synthesis of Unsymmetric Bis(heteroaryl) Selenides by Rhodium‐Catalyzed Exchange Reaction of Heteroaryl Fluorides and Ethers Using Se‐Heteroaryl Carboselenoates

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Various unsymmetric bis(heteroaryl) selenides are synthesized by the rhodium‐catalyzed exchange reaction of heteroaryl fluorides and ethers with Se‐heteroaryl 1‐adamatanecarboselenoates. The synthetic method is applicable to a broad range of five‐ and six‐membered heteroaryl derivatives and provides compounds containing multiple heteroatoms.
Masana Yazaki   +3 more
wiley   +1 more source

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk   +4 more
wiley   +1 more source

Cytotoxic Effects of Chitosan/Retinoic Acid/Albumin Targeted Nanoparticles Loaded with Doxorubicin on Human Hepatoma Cells

open access: yesمجله دانشکده پزشکی اصفهان, 2013
Background: Anthracyclines are used to treat different types of cancer including hepatocellular carcinoma. However, they have various side effects such as cardiotoxicity.
Jaleh Varshosaz   +3 more
doaj  

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

open access: yesEpilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola   +3 more
wiley   +1 more source

One‐Stone‐Two‐Birds Carrier‐Free Nano‐Cocktail Enables Synergistic Eradication of Cancer Cells/Stem Cells in Breast Cancer Treatment

open access: yesExploration, EarlyView.
ABSTRACT Cancer stem cells (CSCs) are widely recognized as the culprits of chemoresistance, tumor metastasis, and relapse. Moreover, most chemotherapeutic drugs not only fail to eliminate CSCs effectively, but also induce the acquisition of stemness characteristics in non‐stem cancer cells. Herein, we propose a cancer cells/CSCs double‐killing modality
Tongyao Zhao   +10 more
wiley   +1 more source

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