Results 121 to 130 of about 349,317 (300)

Syntheses and evaluation of naphthalenyl- and chromenyl-pyrrolyl-benzoic acids as potent and selective retinoic acid receptor α agonists

, 2000
Shigeki Hibi, Katsuya Tagami, K. Kikuchi, Hiroyuki Yoshimura, Kenji Tai, Takayuki Hida, Naoki Tokuhara, Toshihiko Yamauchi, Mitsuo Nagai   +8 more
openalex   +1 more source

Dual Topical Therapy. The Future of Stretch Marks?

JEADV Clinical Practice, EarlyView.
ABSTRACT Striae distensae, or stretch marks, are linear scars that result from mechanical stretching of dermal tissue. They are most prevalent in women and in pregnancy, puberty, and obesity. The psychological and cosmetic symptoms may present a pathological synergy with the physical distress that stretch marks represent, especially if the patient is ...
Vicente Manuel Cisneros Rosell, Ramon Grimalt   +1 more
wiley   +1 more source

Graves’ ophthalmopathy: low-dose dexamethasone reduces retinoic acid receptor-alpha gene expression in orbital fibroblasts [PDF]

, 2018
Sarah Santiloni Cury, Miriane de Oliveira, Maria Teresa De Síbio, Sueli Clara, Renata de Azevedo Melo Luvizotto, Sandro José Conde, Edson Nacib Jorge, Vânia dos Santos Nunes Nogueira, Célia Regina Nogueira, Gláucia Maria Ferreira da Silva Mazeto   +9 more
openalex   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesis [PDF]

, 2011
Shaun Mahony, Esteban O. Mazzoni, Scott McCuine, Richard A. Young, Hynek Wichterle, David K. Gifford   +5 more
openalex   +1 more source

Enhancing Selective Brain Cancer Therapy: Integrating Nanomedicine and Molecular Dynamics to Target the Cancerous Lipid Composition

Nano Select, EarlyView.
Improving selectivity within therapeutic design is critical to ensure targeted delivery to brain tumors. Targeting the cellular membrane composition distinctive of the blood–brain barrier and brain cancer cells is explored in this review. Nanomedicine can be utilized for precise tumor recognition, and detailed mechanistic interactions of therapeutics ...
Mahnoor Kadri, Dominique de Jong‐Hoogland, Martin B. Ulmschneider   +2 more
wiley   +1 more source

Half-site spacing and orientation determines whether thyroid hormone and retinoic acid receptors and related factors bind to DNA response elements as monomers, homodimers, or heterodimers

, 1992
B. M. Forman
openalex   +1 more source

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

Nature, 1992
S. Kliewer, K. Umesono, D. Noonan, R. Heyman, R. Evans   +4 more
semanticscholar   +1 more source

Association of autoimmune diseases with biologic agents targeting type 2 immunity: An observational study using a claims database

Rheumatology &Autoimmunity, EarlyView.
This observational study assessed the association between anti‐type 2 biologic agents and the occurrence of autoimmune diseases using a large real‐world claims database. Anti‐IL‐5 and anti‐IgE therapies were associated with an increased occurrence of autoimmune diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE ...
Shoichiro Inokuchi
wiley   +1 more source

The therapeutic potential of RORγ modulators in the treatment of human disease

Journal of Experimental Pharmacology, 2012
Mi Ra Chang,1 Devrishi Goswami,1 Becky A Mercer,2 Patrick R Griffin1,21Department of Molecular Therapeutics, Scripps Florida, The Scripps Research Institute, Jupiter, FL, USA; 2Translational Research Institute, Scripps Florida, The Scripps Research ...
Chang MR, Goswami D, Mercer BA, Griffin PR   +3 more
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