Results 311 to 320 of about 390,951 (380)

Notch3 enhances the synergistic effect of all-trans retinoic acid and calcipotriol in pancreatic stellate cell activation. [PDF]

J Transl Med
Lian Z, Du WH, Tusup-Han PG, Zhang YX.
europepmc   +1 more source

Editorial: The role of retinoic acid signaling in maintenance and regeneration of the CNS: from mechanisms to therapeutic targeting. [PDF]

Front Mol Neurosci
Corcoran JPT, Mey J.
europepmc   +1 more source

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Retinoic Acid and Retinoic Acid Receptors as Pleiotropic Modulators of the Immune System.

Annual Review of Immunology, 2016
Vitamin A is a multifunctional vitamin implicated in a wide range of biological processes. Its control over the immune system and functions are perhaps the most pleiotropic not only for development but also for the functional fate of almost every cell ...
Alexandre Larangé, H. Cheroutre
semanticscholar   +3 more sources

Retinoids, retinoic acid receptors, and cancer.

Annual Review of Pathology: Mechanisms of Disease, 2011
Retinoids (i.e., vitamin A, all-trans retinoic acid, and related signaling molecules) induce the differentiation of various types of stem cells. Nuclear retinoic acid receptors mediate most but not all of the effects of retinoids.
Xiao-Han Tang, L. Gudas
semanticscholar   +4 more sources

Evolution of retinoic acid receptors and retinoic acid signaling.

Sub-cellular biochemistry, 2014
Retinoic acid (RA) is a vitamin A-derived morphogen controlling important developmental processes in vertebrates, and more generally in chordates, including axial patterning and tissue formation and differentiation. In the embryo, endogenous RA levels are controlled by RA synthesizing and degrading enzymes and the RA signal is transduced by two ...
Juliana Gutierrez-Mazariegos, M. Schubert, V. Laudet   +2 more
semanticscholar   +5 more sources

History of retinoic acid receptors.

Sub-cellular biochemistry, 2014
The discovery of retinoic acid receptors arose from research into how vitamins are essential for life. Early studies indicated that Vitamin A was metabolized into an active factor, retinoic acid (RA), which regulates RNA and protein expression in cells.
D. Benbrook, P. Chambon, C. Rochette-Egly, M. Asson-Batres   +3 more
semanticscholar   +3 more sources

Retinoic Acid Receptors

, 2013
M. Petkovich
semanticscholar   +2 more sources

RETINOIC ACID RECEPTORS AND CANCERS [PDF]

Annual Review of Nutrition, 2004
▪ Abstract  Studies utilizing experimental animals, epidemiological approaches, cellular models, and clinical trials all provide evidence that retinoic acid and some of its synthetic derivatives (retinoids) are useful pharmacological agents in cancer therapy and prevention.
Pu Qin, Dianne Robert Soprano, Kenneth J. Soprano   +2 more
openaire   +2 more sources

Retinoic acid and retinoic acid receptors in development

Molecular Neurobiology, 1995
The vitamin A derivative retinoic acid (RA) and related compounds (retinoids) are utilized as signaling molecules in a diverse array of developmental and physiological regulatory processes, including many important in the developing and mature nervous system. Retinoids function by interaction with high affinity receptors of the nuclear receptor family,
Ronald M. Evans, Henry M. Sucov
openaire   +3 more sources