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Current Opinion in Oncology, 1993
This review highlights recent advances in understanding the mode of action of retinoids at the level of molecular and cellular biology in relation to the new clinical results achieved with retinoids in various malignancies. All-trans-retinoic acid has been established in the clinic as a first-line differentiation therapy for acute promyelocytic ...
E E, Holdener, W, Bollag
+7 more sources
This review highlights recent advances in understanding the mode of action of retinoids at the level of molecular and cellular biology in relation to the new clinical results achieved with retinoids in various malignancies. All-trans-retinoic acid has been established in the clinic as a first-line differentiation therapy for acute promyelocytic ...
E E, Holdener, W, Bollag
+7 more sources
Dermatologic Clinics, 2007
"Retinoid" refers to the naturally occurring compounds with vitamin A activity and to synthetic analogues of retinol. Retinoids are key regulators of differentiation, proliferation, and inflammation. Their successful use in the treatment of various skin diseases and neoplasias has revolutionized the practice of dermatology as well as oncology.
Batya B, Davidovici +2 more
openaire +2 more sources
"Retinoid" refers to the naturally occurring compounds with vitamin A activity and to synthetic analogues of retinol. Retinoids are key regulators of differentiation, proliferation, and inflammation. Their successful use in the treatment of various skin diseases and neoplasias has revolutionized the practice of dermatology as well as oncology.
Batya B, Davidovici +2 more
openaire +2 more sources
Retinoid Specificity of Interphotoreceptor Retinoid-Binding Protein
Biochemistry, 1994Interphotoreceptor retinoid-binding protein (IRBP), the predominant protein in the interphotoreceptor matrix of retina, has been implicated in transfer of retinoids between retinal pigment epithelium and photoreceptor cells. In this work, the interactions of several retinoids with IRBP were studied in order to clarify whether the protein displays ...
Y, Chen, N, Noy
openaire +2 more sources
2015
Retinoids are analogs of vitamin A that exert multiple effects on cellular differentiation and proliferation, the immune system, and embryonic development. A thorough understanding of their mechanisms of action, formulations, administration, and potential adverse effects enables dermatologists to effectively and safely treat patients with a variety of ...
Sorg, Olivier, Saurat, Jean-Hilaire
openaire +4 more sources
Retinoids are analogs of vitamin A that exert multiple effects on cellular differentiation and proliferation, the immune system, and embryonic development. A thorough understanding of their mechanisms of action, formulations, administration, and potential adverse effects enables dermatologists to effectively and safely treat patients with a variety of ...
Sorg, Olivier, Saurat, Jean-Hilaire
openaire +4 more sources