Results 251 to 260 of about 83,475 (294)
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Dermatologic Clinics, 2007
"Retinoid" refers to the naturally occurring compounds with vitamin A activity and to synthetic analogues of retinol. Retinoids are key regulators of differentiation, proliferation, and inflammation. Their successful use in the treatment of various skin diseases and neoplasias has revolutionized the practice of dermatology as well as oncology.
Batya B, Davidovici +2 more
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"Retinoid" refers to the naturally occurring compounds with vitamin A activity and to synthetic analogues of retinol. Retinoids are key regulators of differentiation, proliferation, and inflammation. Their successful use in the treatment of various skin diseases and neoplasias has revolutionized the practice of dermatology as well as oncology.
Batya B, Davidovici +2 more
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Cancer Chemotherapy and Pharmacology, 1979
The early and recent investigations in the field of retinoids and cancer are reviewed. The retinoids, including natural vitamin A compounds and their synthetic analogs, present a new class of substances exerting a prophylactic and a therapeutic effect both in certain experimental tumor models and in certain clinical conditions of preneoplastic and ...
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The early and recent investigations in the field of retinoids and cancer are reviewed. The retinoids, including natural vitamin A compounds and their synthetic analogs, present a new class of substances exerting a prophylactic and a therapeutic effect both in certain experimental tumor models and in certain clinical conditions of preneoplastic and ...
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Retinoids and their receptors in differentiation, embryogenesis, and neoplasia.
, 1991The crucial role of retinoids in controlling differentiation processes has become evident from studies conducted in a variety of in vivo and in vitro systems.
Luigi M. De Luca
semanticscholar +1 more source
Nuclear retinoid receptors and the transcription of retinoid-target genes
Gene, 2004The pleiotropic effects of retinoids are mediated by nuclear retinoid receptors (RARs and RXRs) which are ligand-activated transcription factors. In response to retinoid binding, RAR/RXR heterodimers undergo major conformational changes and orchestrate the transcription of specific gene networks, through binding to specific DNA response elements and ...
Bastien, Julie, Rochette-Egly, Cécile
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Journal of the American Academy of Dermatology, 1984
The retinoids are synthetic derivatives of vitamin A. Isotretinoin (13-cis-retinoic acid) is now being widely used in the United States for severe acne and etretinate is available in Europe and other countries for psoriasis. These drugs are also effective for a number of other skin diseases.
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The retinoids are synthetic derivatives of vitamin A. Isotretinoin (13-cis-retinoic acid) is now being widely used in the United States for severe acne and etretinate is available in Europe and other countries for psoriasis. These drugs are also effective for a number of other skin diseases.
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Journal of Chromatography B: Biomedical Sciences and Applications, 1990
This article reviews the determination of retinoic acids and their metabolites (first-generation retinoids), aromatic retinoids (second generation) and arotinoids (third generation) in biological samples. Because of the sensitivity of the retinoids to isomerization and oxidation, special care has to be taken from sample collection and storage ...
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This article reviews the determination of retinoic acids and their metabolites (first-generation retinoids), aromatic retinoids (second generation) and arotinoids (third generation) in biological samples. Because of the sensitivity of the retinoids to isomerization and oxidation, special care has to be taken from sample collection and storage ...
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Journal of the American Academy of Dermatology, 1988
Retinoids, chemicals that have vitamin A activity, have become important therapeutic agents for a variety of cutaneous disorders, including acne. This paper reviews the history of retinoid use in acne, including retinol, topical tretinoin, topical and systemic isotretinoin, systemic etretinate, and new investigational retinoid molecules.
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Retinoids, chemicals that have vitamin A activity, have become important therapeutic agents for a variety of cutaneous disorders, including acne. This paper reviews the history of retinoid use in acne, including retinol, topical tretinoin, topical and systemic isotretinoin, systemic etretinate, and new investigational retinoid molecules.
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Journal of the American Academy of Dermatology, 2004
Shelley, Sekula-Gibbs +2 more
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Shelley, Sekula-Gibbs +2 more
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Transport of Retinoids by the Interphotoreceptor Retinoid-binding Protein
Nutrition Reviews, 2009In the retina, the interphotoreceptor retinoid-binding protein shuttles retinoids between the retinal pigment epithelium and the rod outer segment. A molecular mechanism for this transport is proposed.
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