Results 191 to 200 of about 16,489,844 (222)

Retinol-binding protein 4, insulin resistance and pregnancy

Metabolism, 2012
Sir, the recent publication on retinol-binding protein 4 (RBP4), insulin resistance (IR) and pregnancy is very interesting [1]. Khovidhunkit et al concluded, “Serum RBP4 levels in pregnancy are not associated with IR.” [1]. This report is very interesting but is discordant with previous reports. RBP4 is discussed in terms of its clinical correlation to
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Retinol-Binding Protein 4 in Patients with Gestational Diabetes Mellitus

Journal of Women's Health, 2010
It is still unknown if serum retinol-binding protein 4 (RBP4) relates to metabolic control and the occurrence of gestational diabetes mellitus (GDM). We studied RBP4 levels in patients with insulin-treated GDM and healthy pregnant women twice during pregnancy.Sixty-three women with GDM and 38 healthy pregnant women were included. Serum RBP4 levels were
Katharina, Klein, Dagmar, Bancher-Todesca, Heinz, Leipold, Martin, Knöfler, Peter, Haslinger, Ammon, Handisurya, Alexandra, Kautzky-Willer, Christof, Worda   +7 more
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Retinol-binding protein 4 is not associated with insulin resistance in pregnancy

Metabolism, 2012
Retinol-binding protein 4 (RBP4) is an adipokine proposed to be specifically associated with insulin resistance (IR). We examined whether serum levels of RBP4 were associated with IR in pregnancy. One hundred seventy-two women with gestational diabetes mellitus (GDM) and 361 pregnant Thai women who did not have GDM but had a positive 50-g glucose ...
Weerapan, Khovidhunkit, Promphan, Pruksakorn, Wanee, Plengpanich, Thipaporn, Tharavanij   +3 more
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Retinol-Binding Protein 4 and Insulin Resistance

New England Journal of Medicine, 2006
To the Editor: Graham et al. (June 15 issue)1 report that serum levels of retinol-binding protein 4 (RBP4) correlated with the magnitude of insulin resistance in various subjects. However, RBP4 and plasma insulin levels were dissociated in subjects who did not have an improvement in insulin sensitivity after exercise.1 Thus, we believe that the ...
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Retinol‐binding protein 4 levels and susceptibility to ischaemic events in men

European Journal of Clinical Investigation, 2014
AbstractBackgroundMany efforts in cardiovascular medicine have been focused in the identification of patients at risk of developing an acute ischaemic event. Biomarker discovery studies have become an essential research area, being proteomic technologies an excellent tool for biomarker identification.
Cubedo, J, Padro, T, Cinca, J, Mata, P, Alonso, R, Badimon, L   +5 more
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Retinol-binding protein-4 and hs-CRP levels in patients with migraine

Neurological Sciences, 2015
Retinol-binding protein-4 (RBP4) and high-sensitivity C-reactive protein (hs-CRP) levels are associated with inflammation in patients with migraine. The release of proinflammatory cytokines during migraine results in recurrent sterile neurogenic inflammation.
Nermin, Tanik, Asuman, Celikbilek, Aslı, Metin, Ayse Yesim, Gocmen, Levent Ertugrul, Inan   +4 more
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Application of an allosteric model to describe the interactions among retinol binding protein 4, transthyretin, and small molecule retinol binding protein 4 ligands

Analytical Biochemistry, 2009
Retinol binding protein 4 (RBP4) is a serum protein that serves as the major transport protein for retinol (vitamin A). Recent reports suggest that elevated levels of RBP4 are associated with insulin resistance and that insulin sensitivity may be improved by reducing serum RBP4 levels. This can be accomplished by administration of small molecules, such
Peter, Coward, Marion, Conn, Jie, Tang, Fei, Xiong, Anthony, Menjares, Jeff D, Reagan   +5 more
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Retinol binding protein 4 and its membrane receptors: a metabolic perspective

Hormone Molecular Biology and Clinical Investigation, 2015
Abstract Nearly a decade of intense research has passed since the first report linking circulating retinol binding protein 4 (RBP4) to the development of insulin resistance. By now, a variety of underlying mechanisms have been identified; some of them are adherent to the canonical role of this circulating protein, which is to ...
Ronja, Fedders, Matthias, Muenzner, Michael, Schupp   +2 more
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Role of retinol-binding protein 4 in the pathogenesis of Type 2 diabetes

Expert Review of Endocrinology & Metabolism, 2008
Retinol-binding protein (RBP)4 is a new adipocytokine that has been associated with insulin resistance. Both RBP4 mRNA expression in adipocytes and serum RBP4 levels are elevated in adipose-specific glucose transporter 4-knockout mice, and elevated circulating RBP4 levels cause insulin resistance by inhibiting phosphatidylinositol 3 kinase activity in ...
Kohzo, Takebayashi, Yoshimasa, Aso, Toshihiko, Inukai   +2 more
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Retinol-binding protein 4 as a risk factor for cholesterol gallstone formation

Molecular and Cellular Biochemistry, 2013
Retinol-binding protein 4 (RBP4) is closely associated with a variety of abnormal glycolipid metabolism diseases such as insulin resistance, obesity, diabetes mellitus, and metabolic syndrome. Part 1 Twenty-four male C57/B6 mice were randomly divided into a normal control group (group C, n = 8), a gallstone group (group G, n = 8), and a medication ...
Tao, Han, Diancai, Zhang, Zan, Fu, Yueming, Sun, Wei, Yang, Cuimei, Yuan   +5 more
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