Results 91 to 100 of about 37,733 (224)
The structures and stabilities of transthyretin tetramers and their complexes with tolcapone or tafamidis bound at the T4‐site, in aqueous solutions without and with 8 M urea, are revealed using SEC‐SWAXS and NMR.Human transthyretin (TTR) is a homotetrameric protein involved in transporting thyroxine (T4) and retinol‐binding protein within serum and ...
Orion Shih+7 more
wiley +1 more source
ABSTRACT Background Clinical practice guidelines recommend additional monitoring in pregnancy for women post‐bariatric surgery, to reduce the risk of maternal and infant complications. Aim To examine if pregnancy care post‐bariatric surgery at an Australian quaternary public hospital is consistent with guidelines and to report on perinatal outcomes ...
Rachel Willims+10 more
wiley +1 more source
Background Retinoids, such as retinol, are widely investigated and utilized in skin care products as a treatment for photoaging but their use is limited by tolerability. Adapinoid (oleyl adapalenate, OA) is a novel third generation retinoid that is a pro‐
Nhi Nguyen+7 more
doaj +1 more source
Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs+12 more
wiley +1 more source
Abstract Background The dental syndrome EOTRH is a painful, progressive dental disease with an unknown aetiology. The often painful nature of EOTRH emphasises the need for a better knowledge of the underlying pathogenic mechanism and risk factors. A comparative analysis of haematological, biochemical and endocrine values in EOTRH‐affected and non ...
Melusine Tretow+2 more
wiley +1 more source
A targeted mass spectrometry‐based metabolomics assay was conducted to identify the impact of stress exposure on the regulation of biological stress pathways in the mdx mouse model of Duchenne muscular dystrophy. We demonstrated a broad shift in the circulating stress‐relevant plasma metabolome associated with stressful scruff handling that was ...
Erynn E. Johnson, James M. Ervasti
wiley +1 more source
Autonomic dysfunction, assessed by the Scales for Outcomes in Parkinson's Disease‐Autonomic Questionnaire, was significantly associated with sarcopenia in patients with Parkinson's disease. Among all autonomic domains, the gastrointestinal score had the strongest predictive ability for sarcopenia.
Motohiro Okumura+3 more
wiley +1 more source
Cellular retinol-binding protein (type two) is abundant in human small intestine.
Human small intestine was found to contain a retinol-binding protein similar to the gut-specific cellular retinol-binding protein, type two [CRBP (II)], described in the rat.
D E Ong, D L Page
doaj
In metabolic dysfunction‐associated steatotic liver disease/metabolic dysfunction‐associated steatohepatitis patients aged <60 years, high serum β‐cryptoxanthin concentrations were inversely associated with CVD mortality. Abstract Aim High cardiovascular disease (CVD) mortality occurred among metabolic dysfunction‐associated steatotic liver disease ...
Qian‐Qian Wang+5 more
wiley +1 more source