Results 101 to 110 of about 53,380 (259)

Pharmacological activation of NO‐cGMP signalling attenuates metabolic dysfunction‐associated steatohepatitis

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth   +14 more
wiley   +1 more source

Novel Histopathologic Features of Diffuse Blue‐Gray Hyperpigmentation Associated With Kratom Use: A Case Report and Literature Review

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Drug‐induced hyperpigmentation accounts for 10%–20% of acquired pigmentary disorders and can be misdiagnosed for other causes such as melasma, post inflammatory changes, or heavy metal deposition. Kratom (Mitragyna speciosa), a Southeast Asian plant with an opioid‐like profile, has been increasingly used in the United States for ...
Rita Kamoua   +4 more
wiley   +1 more source

Vitamin A: retinol.

open access: yes, 2013
Vitamin A: retinol.
Liya Su (23822)   +2 more
core   +1 more source

Investigating transthyretin variants H88R and I107V in amyloid priming: From destabilization to complete dissociation

open access: yesThe FEBS Journal, EarlyView.
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy   +7 more
wiley   +1 more source

Release of retinol and denaturation of its plasma carrier, retinol-binding protein

open access: yes, 1998
Background: Retinol is tightly packed inside the structure of its plasma carrier (retinol-binding protein, RBP). It was found that retinol release from RBP to aqueous solutions is facilitated by either very low pH or very high temperatures (i.e.
Rossi, Gian-Luigi   +4 more
core   +1 more source

Evaluating the suitability of six hydrophobic natural eutectic solvents as the internal phase in a cosmetic cream formulation

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Hydrophobic natural eutectic solvents can function as structural oil phase substitutes in creams prepared by low‐energy processes, enabling sustainable, regulation‐compliant formulations with desirable sensory profiles. Abstract Objective This work evaluates whether hydrophobic natural eutectic solvents can replace the conventional oil phase in ...
A. Verger   +8 more
wiley   +1 more source

Associations between serum retinol and all-cause mortality among adults with prediabetes and diabetes: A cohort study.

open access: yesPLoS ONE
We aimed to explore the associations between serum retinol and all-cause mortality among people with prediabetes and diabetes. The study included 2582 participants with prediabetes and 1654 with diabetes aged ≥40 years from the National Health and ...
Qing Sun, Jie Guo
doaj   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Serum retinol concentration and prevalence of vitamin A deficiency in postpartum women [PDF]

open access: yesRevista Brasileira em Promoção da Saúde, 2011
Objective: To check the serum retinol concentration and assess the nutritional status of postpartum women assisted at Januario Cicco Maternity School, Natal / RN in relation to vitamin A deficiency.
Juliana Cristina de Oliveira Dantas   +3 more
doaj  

Synergistic Benefits of Butyric Acid and Resistant Potato Starch on Growth and Gut Health in Weaned Pigs

open access: yesJournal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Newly‐weaned piglets face challenges such as reduced feed intake, impaired gut function, and susceptibility to post‐weaning diarrhoea, increasing the need for dietary strategies that support gut health and growth. This study investigated the effects of dietary supplementation with butyric acid (BA), resistant potato starch (PS), and their ...
Kathryn Ruth Connolly   +2 more
wiley   +1 more source

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