Results 101 to 110 of about 53,380 (259)
Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth +14 more
wiley +1 more source
ABSTRACT Background Drug‐induced hyperpigmentation accounts for 10%–20% of acquired pigmentary disorders and can be misdiagnosed for other causes such as melasma, post inflammatory changes, or heavy metal deposition. Kratom (Mitragyna speciosa), a Southeast Asian plant with an opioid‐like profile, has been increasingly used in the United States for ...
Rita Kamoua +4 more
wiley +1 more source
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy +7 more
wiley +1 more source
Release of retinol and denaturation of its plasma carrier, retinol-binding protein
Background: Retinol is tightly packed inside the structure of its plasma carrier (retinol-binding protein, RBP). It was found that retinol release from RBP to aqueous solutions is facilitated by either very low pH or very high temperatures (i.e.
Rossi, Gian-Luigi +4 more
core +1 more source
Hydrophobic natural eutectic solvents can function as structural oil phase substitutes in creams prepared by low‐energy processes, enabling sustainable, regulation‐compliant formulations with desirable sensory profiles. Abstract Objective This work evaluates whether hydrophobic natural eutectic solvents can replace the conventional oil phase in ...
A. Verger +8 more
wiley +1 more source
We aimed to explore the associations between serum retinol and all-cause mortality among people with prediabetes and diabetes. The study included 2582 participants with prediabetes and 1654 with diabetes aged ≥40 years from the National Health and ...
Qing Sun, Jie Guo
doaj +1 more source
Bakuchiol: From structural mimicry to systems‐level skin biology
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley +1 more source
Serum retinol concentration and prevalence of vitamin A deficiency in postpartum women [PDF]
Objective: To check the serum retinol concentration and assess the nutritional status of postpartum women assisted at Januario Cicco Maternity School, Natal / RN in relation to vitamin A deficiency.
Juliana Cristina de Oliveira Dantas +3 more
doaj
ABSTRACT Newly‐weaned piglets face challenges such as reduced feed intake, impaired gut function, and susceptibility to post‐weaning diarrhoea, increasing the need for dietary strategies that support gut health and growth. This study investigated the effects of dietary supplementation with butyric acid (BA), resistant potato starch (PS), and their ...
Kathryn Ruth Connolly +2 more
wiley +1 more source

