Results 101 to 110 of about 42,058 (224)

Proteomic Remodeling in the Failing Left Ventricle Adapting to Dyssynchrony

PROTEOMICS – Clinical Applications, Volume 20, Issue 5, September 2026.
ABSTRACT Purpose In heart failure, dyssynchrony is associated with accelerated cardiac remodeling and a worse prognosis. Both restored with resynchronization. We have previously developed a mouse model of dyssynchrony and resynchronization and here assess changes in protein expression within that model.
Karin Ljung, Nitha Aima Muntu, Ulrika Reistam, Jonathan A. Kirk, Marcus Ståhlberg   +4 more
wiley   +1 more source

Cyclic Treatment With WIN 18,446, a Potential Male Contraceptive, is as Effective as Continuous Treatment for Suppression of Spermatogenesis in Mice

Andrology, Volume 14, Issue 6, Page 1472-1478, September 2026.
ABSTRACT Background Retinoic acid plays a critical role in spermatogenesis during both spermatogonial differentiation and spermiation. Mice lacking enzymes that synthesize retinoic acid, Aldh1a1/1a2, in the testes are infertile. WIN 18,446 reversibly inhibits spermatogenesis by inhibiting ALDH1A1/1A2 and is a promising approach to male contraception ...
Jisun Paik, Jessica M. Snyder, Haley A. Martin, John K. Amory   +3 more
wiley   +1 more source

Pharmacological activation of NO‐cGMP signalling attenuates metabolic dysfunction‐associated steatohepatitis

British Journal of Pharmacology, Volume 183, Issue 18, Page 5476-5495, September 2026.
Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth, Malte Roessing, Moritz Lehners, Lisa Dietz, Anja Schmitt, Stephan Hailfinger, Andreas Peter, Leticia Quintanilla‐Martinez, Irene Gonzalez‐Menendez, Ingmar Mederacke, German Ott, Peter Sandner, Matthias Schwab, Robert Feil, Susanne Feil   +14 more
wiley   +1 more source

Last Tile Added to a Mosaic: Phylogenetic Placement of Enigmatic Freshwater Fish Leucalburnus satunini (Cypriniformes: Leuciscidae) Uncovered

Zoologica Scripta, Volume 55, Issue 5, Page 718-727, September 2026.
ABSTRACT Subfamily Leuciscinae, the largest freshwater fish group of the western Palearctic region, has been widely studied, including the phylogenetic relationships between its species and genera. However, until now, one genus completely escaped attention in this regard. Even though several works hypothesised about its evolutionary relationships based
Jasna Vukić, Eleni A. Charmpila, Cüneyt Kaya, Radek Šanda   +3 more
wiley   +1 more source

Maternal vitamin A levels during second and third trimester and associations with offspring's birth weight: a longitudinal cohort <i>post-hoc</i> study. [PDF]

Front Nutr
Dirnena-Fusini I, Stafne SN, Gustafsson MK, Mosti MP, Sujan MAJ, Syversen U, Stunes AK.   +6 more
europepmc   +1 more source

Nutritional Composition of African Catfish (Clarias gariepinus) in Ghana: Effects of Culture Conditions, Feed and Processing

Aquaculture, Fish and Fisheries, Volume 6, Issue 4, August 2026.
This review synthesizes current evidence on the nutritional composition of African catfish (Clarias gariepinus), with emphasis on Ghanaian aquaculture. The species is a valuable source of high‐quality protein, essential amino acids, minerals and vitamins, although lipid composition varies widely.
Amy Atter, Naomi Taye, Crossby Osei Tutu, Bernard Kwabena Asiedu, Reuben Acheampong, Hayford Ofori, Stephen Nketia, Richard Yaw Otwey, Christopher Galley, Frank Peget, Jackline Boateng, Patricia Mensah, Stacy Ayitey, Eric Dogbey, Seth Agyakwah, Wisdom Amoa‐Awua   +15 more
wiley   +1 more source

Retinol-Loaded Mannosylerythritol Lipid Nanoliposome for Enhanced Human Skin Penetration. [PDF]

Skin Res Technol
Park HW, Yoo DS, Jeong CJ, Park SN.
europepmc   +1 more source

Pre‐Diagnostic Plasma Carotenoids, Tocopherols and Retinol Levels, and Risk of Amyotrophic Lateral Sclerosis

Annals of Neurology, Volume 100, Issue 2, Page 426-435, August 2026.
Objective Our goal was to examine whether pre‐diagnostic plasma carotenoids and tocopherols are associated with amyotrophic lateral sclerosis (ALS). Methods A nested case–control study within 4 United States cohorts, where 154 participants with pre‐diagnostic blood‐draw, were diagnosed during follow‐up with amyotrophic lateral sclerosis (ALS). Controls
Éilis J. O'Reilly, Kjetil Bjornevik, Jeremy D. Furtado, Alpa V. Patel, Ying Wang, Laurence N. Kolonel, Loïc Le Marchand, Alberto Ascherio   +7 more
wiley   +1 more source

Transthyretin and Vitamin A Metabolism: A Review for the Cardiac Amyloidosis Specialist. [PDF]

J Cardiovasc Dev Dis
Brown D, Modak V, Altic A, Al Zuwayny A, Tauras J.   +4 more
europepmc   +1 more source

CLRN1 Variants in Müller Cells Cause Mitochondrial Dysfunction in USH3A Retinal Organoids

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
We generated retinal organoids from a patient with USH3A and performed single‐cell RNA sequencing. CLRN1 was specifically expressed in Müller cells, where its variants led to mitochondrial dysfunction and photoreceptor degeneration. ABSTRACT Background Usher syndrome 3A (USH3A), caused by mutations in the CLRN1 gene, leads to retinitis pigmentosa and ...
Rui Zhang, Xinbo Ji, Han Yu, Jingwen Xu, Yu Wang, Ping Sun, Yingxin Wang, Yao Tang, Zexin Zhan, Yichang Jiao, Didi Shan, Pengfei Lin, Dong‐dong Wang, Yuying Zhao, Xianyang Liu, Chuanzhu Yan, Jianqiao Li, Mingfeng Li, Fuchen Liu, Shengping Hou   +19 more
wiley   +1 more source