Results 1 to 10 of about 15,495 (243)

Comparative studies of retinol transport in plasma

Journal of Lipid Research, 1973
The comparative immunology and biochemistry of plasma retinol transport were studied using radioimmunoassays previously developed for human and for rat retinol-binding protein (RBP).
Yasutoshi Muto, Frank Rees Smith, DeWitt S. Goodman   +2 more
doaj   +3 more sources

Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection

eLife, 2014
Retinol plays a vital role in the immune response to infection, yet proteins that mediate retinol transport during infection have not been identified.
Mehabaw G Derebe, Clare M Zlatkov, Sureka Gattu, Kelly A Ruhn, Shipra Vaishnava, Gretchen E Diehl, John B MacMillan, Noelle S Williams, Lora V Hooper   +8 more
doaj   +3 more sources

Transthyretin and Vitamin A Metabolism: A Review for the Cardiac Amyloidosis Specialist [PDF]

Journal of Cardiovascular Development and Disease
Transthyretin (TTR) amyloidosis is a systemic, progressive, and fatal disease. TTR is integral in vitamin A (retinol) transport via its binding to retinol binding protein 4 (RBP4).
Donclair Brown, Vishakha Modak, Aladin Altic, Ali Al Zuwayny, James Tauras   +4 more
doaj   +2 more sources

Maternal obesity remodels nutrient transport transcriptional programs in early mouse embryonic and extraembryonic cell lineages [PDF]

Molecular Metabolism
Background: Maternal obesity increases the risk of congenital anomalies and later-life metabolic disease in offspring. Still, underlying mechanisms remain unclear, particularly in extraembryonic lineages at the maternal–fetal interface, which remain ...
Amalia Caballero, Lijun Chi, Paul Delgado-Olguín   +2 more
doaj   +2 more sources

Metabolism and secretion of retinol transport complex in acute renal failure

Journal of Lipid Research, 1991
Tissue uptake and distribution of retinol from circulatory vitamin A transport complex was studied in order to determine the origin of the increased serum retinol in rats with short-term acute renal failure.
TH Gerlach, MH Zile
doaj   +3 more sources

Beyond a gatekeeper: the non-classical signaling role of STRA6 in driving endothelial senescence and atherosclerosis [PDF]

Frontiers in Immunology
Endothelial cell (EC) senescence is a fundamental driver of atherosclerosis. This review posits that the primary pathogenic role of Stimulated by Retinoic Acid 6 (STRA6) in the endothelium is not its canonical vitamin A transport but its non-classical ...
Yong Yuan, Jia Wang, Yunfang Zhang, Yan Yu, Weicheng Shi, Sulian Chen, Ye Kuang, Lei Feng   +7 more
doaj   +2 more sources

Retinol tracing within murine neural retina reveals cell type-specific retinol transport and distribution. [PDF]

J Clin Invest
11-cis-Retinal is essential for light perception in mammalian photoreceptors (PRs), and aberrations in retinoid transformations cause severe retinal diseases. Understanding these processes is crucial for combating blinding diseases. The visual cycle, operating within PRs and the retinal pigment epithelium (RPE), regenerates 11-cis-retinal to sustain ...
Engfer ZJ, Palczewska G, Du SW, Zhang J, Dong Z, Menezes CR, Wang J, Shao J, Tucker BA, Mullins RF, Chen R, Kiser PD, Palczewski K.   +12 more
europepmc   +3 more sources

Real-time analyses of retinol transport by the membrane receptor of plasma retinol binding protein. [PDF]

J Vis Exp, 2013
Vitamin A is essential for vision and the growth/differentiation of almost all human organs. Plasma retinol binding protein (RBP) is the principle and specific carrier of vitamin A in the blood. Here we describe an optimized technique to produce and purify holo-RBP and two real-time monitoring techniques to study the transport of vitamin A by the high ...
Kawaguchi R, Zhong M, Sun H.
europepmc   +4 more sources

The Potential Role of Retinol-Binding Protein 4 in Heart Failure: A Review [PDF]

Reviews in Cardiovascular Medicine
Heart failure (HF) is a heterogeneous clinical syndrome, the prevalence of which is increasing among younger adults, promoting global concern due to its significant morbidity and mortality.
Jiayi Liu, Yaping Wang
doaj   +2 more sources

Retinol-binding protein: the transport protein for vitamin A in human plasma [PDF]

Journal of Clinical Investigation, 1968
Vitamin A circulates in human plasma as retinol bound to a specific transport protein. This protein differs from the known low and high density plasma lipoproteins and has a hydrated density greater than 1.21. In order to study this protein, volunteers were injected intravenously with retinol-15-(14)C.
Amiram Raz, Dewitt S Goodman
exaly   +3 more sources