Results 21 to 30 of about 15,860 (203)
Cells, 2020 Dietary vitamin A/all-trans retinol/ROL plays a critical role in human vision. ROL circulates bound to the plasma retinol-binding protein (RBP4) as RBP4-ROL. In the eye, the STRA6 membrane receptor binds to circulatory RBP4 and internalizes ROL. STRA6 is,
Ashish K. Solanki +8 more
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Evidence for an Essential Role of Megalin in Transepithelial Transport of Retinol [PDF]
Journal of the American Society of Nephrology, 1999 Abstract. Transepithelial transport of retinol is linked to retinol-binding protein (RBP), which is taken up and also synthesized in a number of epithelia. By immunocytochemistry of human, rat, and mouse renal proximal tubules, a strong staining in apical endocytic vacuoles, lysosomes, endoplasmic reticulum ...
Christensen, Erik Ilsø +8 more
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A multicompartmental model of vitamin A kinetics in rats with marginal liver vitamin A stores.
Journal of Lipid Research, 1985 A linear, first-order, constant-coefficient multicompartmental model is presented which describes the dynamics of [3H]retinol turnover in adult rats with normal plasma retinol concentrations but low liver stores (less than 100 micrograms of retinol ...
M H Green, L Uhl, J B Green
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Retinol Esterification Activity Contributes to Retinol Transport in Stellate Cells.
Cell Structure and Function, 1999 The mechanisms of retinol transport and accumulation in hepatic stellate cells (HSC) remain to be elucidated. Our previous studies suggested that retinol esterification activity, particularly lecithin:retinol acyltransferase (LRAT) activity, in liver retinoid metabolism is important to elucidate the relationship between retinol uptake by HSC and the ...
T, Matsuura +3 more
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Scientific Reports, 2023 This paper expands the current state of knowledge on impact of retinoids on redox status of cytochrome c in cancers. Little is known how the expression of cytochromes may influence the development of cancers.
Jakub Maciej Surmacki, Halina Abramczyk
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ACS Chemical Biology, 2010 Transthyretin (TTR) is a plasma hormone carrier protein associated with hereditary and senile forms of systemic amyloid disease, wherein slow tetramer disassembly is thought to be an obligatory step. Plasma transport of retinol is carried out exclusively by the retinol-binding protein (RBP), through complexation with transthyretin.
Hyung, Suk-Joon +2 more
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Serum and intracellular retinol transport in the equine [PDF]
British Journal of Nutrition, 1982 1. Serum and intracellular distribution of retinol was determined in equines maintained on four levels of vitamin A intake.2. The form of retinol transported in serum was determined by gel filtration and chromatography to be a complex of retinol bound to a protein of molecular weight (MW) of approximately 20000, which was in turn complexed probably ...
D. Sklan, Susan Donoghue
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Journal of Lipid Research, 1977 Studies were conducted to explore vitamin A transport in the non-mammalian vertebrates, especially Pisces, Amphibia, and Reptilia, and to isolate and partially characterize piscine retinol-binding protein.
Y Shidoji, Y Muto
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Retinoid-binding proteins: similar protein architectures bind similar ligands via completely different ways. [PDF]
PLoS ONE, 2012 BACKGROUND: Retinoids are a class of compounds that are chemically related to vitamin A, which is an essential nutrient that plays a key role in vision, cell growth and differentiation. In vivo, retinoids must bind with specific proteins to perform their
Yu-Ru Zhang, Yu-Qi Zhao, Jing-Fei Huang
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Journal of Lipid Research, 1995 Retinol-binding protein (RBP) is the specific blood carrier for the transport of retinol (vitamin A) to target tissues. As the kidney is involved in RBP metabolism, the analysis of RBP species in the serum of patients with chronic renal failure (CRF) was
S. Jaconi +4 more
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