Results 31 to 40 of about 15,860 (203)

Vitamin A transport and the transmembrane pore in the cell-surface receptor for plasma retinol binding protein. [PDF]

open access: yesPLoS ONE, 2013
Vitamin A and its derivatives (retinoids) play diverse and crucial functions from embryogenesis to adulthood and are used as therapeutic agents in human medicine for eye and skin diseases, infections and cancer.
Ming Zhong   +4 more
doaj   +1 more source

Effects of acute inflammation on plasma retinol, retinol-binding protein, and its mRNA in the liver and kidneys of vitamin A-sufficient rats

open access: yesJournal of Lipid Research, 1996
The acute inflammatory response to tissue injury and infection is associated with low concentrations of plasma retinol and its specific transport proteins, retinol-binding protein (RBP) and transthyretin (TTR).
F J Rosales   +4 more
doaj   +1 more source

Production of functional human vitamin A transporter/RBP receptor (STRA6) for structure determination. [PDF]

open access: yesPLoS ONE, 2015
STRA6 is a plasma membrane protein that mediates the transport of vitamin A, or retinol, from plasma retinol binding protein (RBP) into the cell. Mutations in human STRA6 are associated with Matthew-Wood syndrome, which is characterized by severe ...
Conor J Breen   +5 more
doaj   +1 more source

Molecular basis for the interaction of cellular retinol binding protein 2 (CRBP2) with nonretinoid ligands

open access: yesJournal of Lipid Research, 2021
Present in the small intestine, cellular retinol binding protein 2 (CRBP2) plays an important role in the uptake, transport, and metabolism of dietary retinoids.
Josie A. Silvaroli   +6 more
doaj   +1 more source

Impact of vitamin A transport and storage on intestinal retinoid homeostasis and functions

open access: yesJournal of Lipid Research, 2021
: Lecithin:retinol acyltransferase and retinol-binding protein enable vitamin A (VA) storage and transport, respectively, maintaining tissue homeostasis of retinoids (VA derivatives).
Maryam Honarbakhsh   +15 more
doaj   +1 more source

Isolation and Properties of a Human Retinol-transporting Protein

open access: yesJournal of Biological Chemistry, 1971
A human retinol-transporting protein has been isolated from the urine of patients with tubular proteinuria. The protein separated into four fractions in the last two purification steps (sulfoethyl Sephadex chromatography and DEAE-Sephadex chromatography). The yield of purified retinol-binding protein (RBP) was 33 to 41% of the amount in concentrates of
P A, Peterson, I, BerggÄrd
openaire   +2 more sources

Retinol metabolism in rats with low vitamin A status: a compartmental model

open access: yesJournal of Lipid Research, 1990
A compartmental model was developed to describe the metabolism of vitamin A in rats with low vitamin A status maintained by a low dietary intake of vitamin A (approximately 2 micrograms retinol equivalents/day).
KC Lewis, MH Green, JB Green, LA Zech
doaj   +1 more source

Identification of SNPs in Cellular Retinol Binding Protein 1 and Cellular Retinol Binding Protein 3 Genes and Their Associations with Laying Performance Traits in Erlang Mountainous Chicken [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2014
CRBP1 (cellular retinol binding protein 1) and CRBP3 (cellular retinol binding protein 3), are important components of the retinoid signaling pathway and take part in vitamin A absorption, transport and metabolism.
Yan Wang   +4 more
doaj   +1 more source

Real-time Analyses of Retinol Transport by the Membrane Receptor of Plasma Retinol Binding Protein

open access: yesJournal of Visualized Experiments, 2013
Vitamin A is essential for vision and the growth/differentiation of almost all human organs. Plasma retinol binding protein (RBP) is the principle and specific carrier of vitamin A in the blood. Here we describe an optimized technique to produce and purify holo-RBP and two real-time monitoring techniques to study the transport of vitamin A by the high ...
Riki, Kawaguchi, Ming, Zhong, Hui, Sun
openaire   +3 more sources

Vitamin A metabolism is changed in donors after living-kidney transplantation: an observational study

open access: yesLipids in Health and Disease, 2011
Background The kidneys are essential for the metabolism of vitamin A (retinol) and its transport proteins retinol-binding protein 4 (RBP4) and transthyretin.
Henze Andrea   +6 more
doaj   +1 more source

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