Vitamin A transport and the transmembrane pore in the cell-surface receptor for plasma retinol binding protein. [PDF]
Vitamin A and its derivatives (retinoids) play diverse and crucial functions from embryogenesis to adulthood and are used as therapeutic agents in human medicine for eye and skin diseases, infections and cancer.
Ming Zhong +4 more
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The acute inflammatory response to tissue injury and infection is associated with low concentrations of plasma retinol and its specific transport proteins, retinol-binding protein (RBP) and transthyretin (TTR).
F J Rosales +4 more
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Production of functional human vitamin A transporter/RBP receptor (STRA6) for structure determination. [PDF]
STRA6 is a plasma membrane protein that mediates the transport of vitamin A, or retinol, from plasma retinol binding protein (RBP) into the cell. Mutations in human STRA6 are associated with Matthew-Wood syndrome, which is characterized by severe ...
Conor J Breen +5 more
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Present in the small intestine, cellular retinol binding protein 2 (CRBP2) plays an important role in the uptake, transport, and metabolism of dietary retinoids.
Josie A. Silvaroli +6 more
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Impact of vitamin A transport and storage on intestinal retinoid homeostasis and functions
: Lecithin:retinol acyltransferase and retinol-binding protein enable vitamin A (VA) storage and transport, respectively, maintaining tissue homeostasis of retinoids (VA derivatives).
Maryam Honarbakhsh +15 more
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Isolation and Properties of a Human Retinol-transporting Protein
A human retinol-transporting protein has been isolated from the urine of patients with tubular proteinuria. The protein separated into four fractions in the last two purification steps (sulfoethyl Sephadex chromatography and DEAE-Sephadex chromatography). The yield of purified retinol-binding protein (RBP) was 33 to 41% of the amount in concentrates of
P A, Peterson, I, BerggÄrd
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Retinol metabolism in rats with low vitamin A status: a compartmental model
A compartmental model was developed to describe the metabolism of vitamin A in rats with low vitamin A status maintained by a low dietary intake of vitamin A (approximately 2 micrograms retinol equivalents/day).
KC Lewis, MH Green, JB Green, LA Zech
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Identification of SNPs in Cellular Retinol Binding Protein 1 and Cellular Retinol Binding Protein 3 Genes and Their Associations with Laying Performance Traits in Erlang Mountainous Chicken [PDF]
CRBP1 (cellular retinol binding protein 1) and CRBP3 (cellular retinol binding protein 3), are important components of the retinoid signaling pathway and take part in vitamin A absorption, transport and metabolism.
Yan Wang +4 more
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Real-time Analyses of Retinol Transport by the Membrane Receptor of Plasma Retinol Binding Protein
Vitamin A is essential for vision and the growth/differentiation of almost all human organs. Plasma retinol binding protein (RBP) is the principle and specific carrier of vitamin A in the blood. Here we describe an optimized technique to produce and purify holo-RBP and two real-time monitoring techniques to study the transport of vitamin A by the high ...
Riki, Kawaguchi, Ming, Zhong, Hui, Sun
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Background The kidneys are essential for the metabolism of vitamin A (retinol) and its transport proteins retinol-binding protein 4 (RBP4) and transthyretin.
Henze Andrea +6 more
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