Results 51 to 60 of about 15,495 (243)

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

open access: yesAdvanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou   +5 more
wiley   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

open access: yesAdvanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du   +11 more
wiley   +1 more source

Vitamin A equivalency of ß-carotene in healthy adults: limitation of the extrinsic dual-isotope dilution technique to measure matrix effect

open access: yes, 2009
Data on the vitamin A equivalency of ß-carotene in food are inconsistent. We quantified the vitamin A equivalency (¿g) of ß-carotene in two diets using the dual-isotope dilution technique and the oral¿faecal balance technique.
Lieshout, M. van   +17 more
core   +1 more source

Adaptive evolution of the STRA6 genes in mammalian. [PDF]

open access: yesPLoS ONE, 2014
Stimulated by retinoic acid 6 (STRA6) is the receptor for retinol binding protein and is relevant for the transport of retinol to specific sites such as the eye.
Jianghong Wu   +7 more
doaj   +1 more source

Resistant Peanut Genotype Reprograms Rhizosphere Metabolism to Enhance Bacterial Wilt Suppression

open access: yesAdvanced Science, EarlyView.
The resistant peanut genotype selectively recruits beneficial bacteria, which coincides with the activation of salicylic acid (SA)‐dependent systemic acquired resistance (SAR) against Ralstonia solanacearum. Keystone rhizosphere metabolites are positively correlated with both beneficial microbiome assembly and SAR gene expression.
Rui Ren   +20 more
wiley   +1 more source

Real-time analysis of STRA6-catalyzed transport of retinol from holo-RBP to EGFP-CRBP-I.

open access: yes, 2013
A. Schematic diagram of the use of retinol-EGFP FRET to monitor the transport of retinol from holo-RBP to EGFP-CRBP-I. FRET is indicated by an orange arrow. B and C.
Mariam Ter-Stepanian (478956)   +4 more
core   +1 more source

The Extracellular Protein, Transthyretin Is an Oxidative Stress Biomarker

open access: yesFrontiers in Physiology, 2019
The extracellular protein, transthyretin is responsible for the transport of thyroxin and retinol binding protein complex to the various parts of the body.
Meesha Sharma   +3 more
doaj   +1 more source

Degradation Mechanisms, Encapsulation‐Based Stabilization, and Analytical Detection of Vitamin A

open access: yesJournal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Vitamin A is an important lipid‐soluble micronutrient essential for vision, immune function, and overall growth and development. However, vitamin A is unstable and susceptible to environmental factors because of its conjugated structure and inherent chemical reactivity.
Latheesha Abeywardana   +5 more
wiley   +1 more source

Retinol semisolid preparations in cosmetics: transcutaneous permeation mechanism and behaviour

open access: yesScientific Reports
Retinol is widely used to treat skin ageing because of its effect on cell differentiation, proliferation and apoptosis. However, its potential benefits appear to be limited by its skin permeability.
Yuan Wang   +9 more
doaj   +1 more source

Pt‐TiO2 mesoporous nanosystem co‐delivering phlorezin enables synergistic sonodynamic‐chemoimmunotherapy for hepatocellular carcinoma via directly targeting DDX5 and metabolic reprogramming modulation

open access: yesBMEMat, EarlyView.
Abstract Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer‐related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt‐TiO2 nanoparticles for the co‐delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic ...
Kairui Liu   +13 more
wiley   +1 more source

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