Results 51 to 60 of about 15,860 (203)

Retinol semisolid preparations in cosmetics: transcutaneous permeation mechanism and behaviour

open access: yesScientific Reports
Retinol is widely used to treat skin ageing because of its effect on cell differentiation, proliferation and apoptosis. However, its potential benefits appear to be limited by its skin permeability.
Yuan Wang   +9 more
doaj   +1 more source

A Narrative Review of the Role of Transthyretin in Health and Disease

open access: yesNeurology and Therapy, 2020
Transthyretin (TTR) is a tetrameric transport protein highly conserved through vertebrate evolution and synthesized in the liver, choroid plexus, and retinal pigment epithelium. TTR transports the thyroid hormone thyroxine and the retinol-binding protein
Marcia Almeida Liz   +5 more
doaj   +1 more source

Exome analysis identified a novel mutation in the RBP4 gene in a consanguineous pedigree with retinal dystrophy and developmental abnormalities. [PDF]

open access: yesPLoS ONE, 2012
Retinitis Pigmentosa (RP) is a common form of retinal degeneration characterized by photoreceptor degeneration and retinal pigment epithelium (RPE) atrophy causing loss of visual field and acuities.
Catherine Cukras   +11 more
doaj   +1 more source

Valorization of Citrus Waste for Recovery of Nutritional and Bioactive Compounds: A Comprehensive Review

open access: yesFuture Postharvest and Food, EarlyView.
The various citrus wastes, including the citrus fruit peels, pulp remaining after extraction of juice, and seeds, are the sources of bioactive compounds. The waste parts of oranges, lemons, limes, grapefruits, and mandarins contain the bioactive compounds, flavonoids, ascorbic acid, essential oils, and carotenoids.
Monika   +4 more
wiley   +1 more source

The Extracellular Protein, Transthyretin Is an Oxidative Stress Biomarker

open access: yesFrontiers in Physiology, 2019
The extracellular protein, transthyretin is responsible for the transport of thyroxin and retinol binding protein complex to the various parts of the body.
Meesha Sharma   +3 more
doaj   +1 more source

Genetic influences on circulating retinol and its relationship to human health

open access: yesNature Communications
Retinol is a fat-soluble vitamin that plays an essential role in many biological processes throughout the human lifespan. Here, we perform the largest genome-wide association study (GWAS) of retinol to date in up to 22,274 participants. We identify eight
William R. Reay   +11 more
doaj   +1 more source

Adaptive evolution of the STRA6 genes in mammalian. [PDF]

open access: yesPLoS ONE, 2014
Stimulated by retinoic acid 6 (STRA6) is the receptor for retinol binding protein and is relevant for the transport of retinol to specific sites such as the eye.
Jianghong Wu   +7 more
doaj   +1 more source

Improvement in sequelae of chronic liver disease in patients with Alagille syndrome treated with maralixibat

open access: yesJPGN Reports, EarlyView.
Abstract Maralixibat (MRX) is an orally administered, small‐molecule ileal bile acid transporter (IBAT) inhibitor used in the treatment of cholestatic pruritus in conditions such as Alagille syndrome (ALGS). MRX's beneficial effects on cholestatic pruritus are well described, however its effects on patients’ clinical manifestations of hepatic disease ...
Tin Bo Nicholas Lam   +2 more
wiley   +1 more source

Retinol-binding protein 4 in skeletal and cardiac muscle: molecular mechanisms, clinical implications, and future perspectives

open access: yesFrontiers in Cell and Developmental Biology
Retinol-binding protein 4 (RBP4) has emerged as a critical adipokine involved in the pathophysiology of metabolic and cardiovascular diseases. Beyond its classical role in retinol transport, RBP4 influences insulin resistance, inflammation, lipid ...
Kangzhen Zhang   +3 more
doaj   +1 more source

Retinol transport system in cattle and purification of retinol-binding protein from bovine serum.

open access: yesThe Japanese Journal of Veterinary Science, 1989
Retinol transport system in cattle was investigated, followed by the purification and characterization of bovine serum retinol-binding protein (RBP). Gel filtration of serum from cow produced two retinol peaks, peak 1 and 2. The major, peak 1 having higher molecular weight corresponded to the retinol peak from human serum which consisted of RBP and ...
MIYAMOTO, Toru   +5 more
openaire   +3 more sources

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